Hostname: page-component-cd9895bd7-7cvxr Total loading time: 0 Render date: 2024-12-25T00:56:29.697Z Has data issue: false hasContentIssue false
  • English
  • Français

A Case of Mongolism in DZ Female Twins Studied at 10 and then at 43 Years of Age

Published online by Cambridge University Press:  01 August 2014

William Walter Greulich ,
W. Roy Breg Jr. ,
Charles S. Culotta ,
Chris C. Plato  and
Herman Yannet
William Walter Greulich*
Affiliation:
National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA Department of Anatomy, Stanford University School of Medicine, Stanford, California, USA
W. Roy Breg Jr.
Affiliation:
Southbury Training School, Southbury, Connecticut, USA
Charles S. Culotta
Affiliation:
291 Whitney Avenue, New Haven, Connecticut, USA
Chris C. Plato
Affiliation:
National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA
Herman Yannet
Affiliation:
Southbury Training School, Southbury, Connecticut, USA
*
Department of Anatomy, Stanford University School of Medicine, Stanford, California 94305, USA

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

A pair of female mongoloid twins was studied when they were ten years old and, again, some thirty years later. A careful comparison was made of the similarities and differences between them in features or traits which have proved to be useful in determining the zygosity of like-sexed twins.

Though some of these characters can be, and frequently are, considerably modified in the presence of mongolism and so lose part of their value for that purpose, the differences noted in these twins, both as children and as middle-aged adults, are thought to outweigh their similarities and so warrant the conclusion that they are, indeed, dizygotic.

Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 24 , Issue 1-2 , January 1975 , pp. 47 - 61
Copyright
Copyright © The International Society for Twin Studies 1975

References

REFERENCES

Brousseau, K. 1928. Mongolism (Revised by H.G. Brainard). Baltimore, Md.: Williams & Wilkins Co.Google Scholar
Fielding, D.W., Walker, S. 1972. Dizygotic twins with Down's syndrome. Arch. Dis. Child., 47: 971–973.CrossRefGoogle ScholarPubMed
Fraser, J., Mitchell, A. 1876. Kalmuc Idiocy: Report of a case with autopsy. With notes on sixty-two cases. J. Ment. Sci., 22: 169–179.CrossRefGoogle Scholar
Greulich, W.W. 1960. Skeletal feature visible in the roentgenogram of the hand and wrist which can be used for establishing individual identification. Am J. Roentgenol. Radium Ther. Nucl. Med., 83: 756–764.Google ScholarPubMed
Greulich, W.W. 1969. The incidence of dysplasia of the middle phalanx of the fifth finger in normal Japanese, in some American Indian groups, and in Caucasians with Down's Syndrome. In Kretchmer, N. and Walcher, D.N. (eds.): Environmental Influences on Genetic Expression. Washington, D.C.: U.S. Govt. Printing Office.Google Scholar
Greulich, W.W. 1973. A comparison of the dysplastic middle phalanx of the fifth finger in mentally normal Caucasians, Mongoloids, and Negroes with that of individuals of the same racial groups who have Down's Syndrome. Am. J. Roentgenol. Radium Ther. and Nucl. Med., 118: 259–281.CrossRefGoogle Scholar
Krivit, W., Good, R.A. 1957. Simultaneous occurrence of mongolism and leukemia. Report of a nation-wide survey. Am. J. Dis. Child., 94: 289–293.CrossRefGoogle Scholar
McDonald, A.D. 1964. Mongolism in twins. J. Med. Genet., 1: 39–41.CrossRefGoogle ScholarPubMed
Naiman, J.L., Oski, F.A., Mellman, W.J. 1965. Phosphokinase activity of erythrocytes in mongolism. Lancet, 1: 821.CrossRefGoogle ScholarPubMed
Mittwoch, U. 1958. The polymorphonuclear lobe count and its relation to the total leukocyte count. J. Ment. Dene. Res., 2: 75–80.Google Scholar
Penrose, L.S., Smith, G.F. 1966. Down's Anomaly. London: J. & A. Churchill.Google Scholar
Stewart, A.M. 1961. Aetiology of childhood malignancies: congenitally determined leukemias. Br. Med. J., 1: 452–460.CrossRefGoogle Scholar
Wolff, de E., Schärer, K., Lejeune, J. 1962. Contribution à l'étude des jumeaux mongoliens. Un cas de monozygotisme hétérokaryote. Helv. Pediatr. Acta, 17: 301–328.Google Scholar