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Bloodtyping and Twin Zygosity. Reassessment and Extension

Published online by Cambridge University Press:  01 August 2014

Ronald S. Wilson
Ronald S. Wilson*
Affiliation:
University of Louisville School of Medicine, Kentucky
*
Louisville Twin Study, P.O. Box 35260, Louisville, KY 40232

Abstract

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The determination of twin zygosity by bloodtyping is reconsidered, and the model for the individual case is reformulated. The crucial diagnostic question may be phrased as follows: Given the particular array of bloodgroup phenotypes that the twins display and are concordant for, how might this array have been obtained by a pair of dizygotic twins, and how might the array have been obtained by a monozygotic pair? The solution yields a differential probability value that is uniquely tailored to the actual phenotype array shown. The procedure offers a coherent and more direct method for arriving at the needed probability figures, and it is recommended to supersede previous methods. Some similarities and differences between the methods are discussed.

Keywords

Twin zygosity diagnosisBloodtypingGenetic markers
Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 29 , Issue 2 , April 1980 , pp. 103 - 120
Copyright
Copyright © The International Society for Twin Studies 1980

References

REFERENCES

1.Lykken, DT (1978): The diagnosis of zygosity in twins. Behav Genet 8:437–473.Google Scholar
2.Smith, SM, Penrose, LS (1955): Monozygotic and dizygotic twin diagnosis. Ann Hum Genet 19:273–289.Google Scholar
3.Sutton, HE, Clark, PJ, Schull, WJ (1955): The use of multi-allele genetic characters in the diagnosis of twin zygosity. Am J Hum Genet 7:180–188.Google ScholarPubMed
4.Wilson, RS (1970): Bloodtyping and twin zygosity. Hum Hered 20:30–56.Google Scholar