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Antenatal Genetic Studies in Twin Pregnancies

Published online by Cambridge University Press:  01 August 2014

F.O. Redwine ,
D.P. Cruikshank  and
J. Brown
F.O. Redwine*
Affiliation:
Departments of Obstetrics and Gynecology and of Human Genetics, Medical College of Virginia. Richmond
D.P. Cruikshank
Affiliation:
Departments of Obstetrics and Gynecology and of Human Genetics, Medical College of Virginia. Richmond
J. Brown
Affiliation:
Departments of Obstetrics and Gynecology and of Human Genetics, Medical College of Virginia. Richmond
*
Department of Obstetrics and Gynecology, Medical College of Virginia, P.O. Box 34, Richmond, VA 23298, USA

Abstract

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The diagnosis of multiple gestation at the time of genetic amniocentesis is a routine occurrence. In a combined series of 2765 patients referred for antenatal genetic studies from the Medical College of Virginia and the University of Iowa, 34 twin pregnancies were encountered (1.2%). Twenty-six of the patients with twins were referred for advanced maternal age. The other indications were previous neural tube defects (1), previous trisomy 21 (2), known carriers of Tay Sachs disease (2), previous Turner's syndrome (1), family history of trisomy 21 (1), and one pregnancy was referred because of an abnormal ultrasound. Amniocentesis procedures, outcome of the twin pregnancies, and genetic counseling issues, are discussed.

Keywords

Antenatal diagnosisTwin pregnancyGenetic counseling
Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 33 , Issue 1 , January 1984 , pp. 39 - 41
Copyright
Copyright © The International Society for Twin Studies 1984