This contribution presents a novel simulation for a fixed-wing aircraft powered by gas turbine engines and advanced propellers (turboprops). The work is part of a large framework for the simulation of aircraft flight through a multi-disciplinary approach. Novel numerical methods are presented for flight mechanics, turboprop engine simulation (in direct and inverse mode), and propeller dynamics. We present in detail the integration of the propeller with the airframe, aircraft and tonal noise model. At the basic level, we address a shortfall in multi-disciplinary integration in turboprop-powered aircraft, including economical operations and environmental emissions (exhausts and noise). The models introduced are based on first principles, supplied with semi-empirical correlations, if required. Validation strategies are presented for component-level analysis and system integration. Results are presented for aerodynamics, specific air range, optimal cruise conditions, payload-range performance, and propeller noise. Selected results are shown for the ATR 72-500, powered by PW127M turboprop engines and F568-1 propellers.