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Medication in the treatment of alcohol dependence

Published online by Cambridge University Press:  02 January 2018

Jonathan Chick
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Social, cultural, emotional and biological influences determine whether people drink to excess and whether they then experience harm or cause harm to others (Cook, 1994). Psychosocial treatments for alcohol dependence are only modestly successful, with most studies finding that at least 50% of patients return to harmful drinking in the following year. In the past decade there has been new evidence for the role of pharmacological treatments in reducing harm from drinking and in preventing relapse.

Type
Research Article
Information
Advances in Psychiatric Treatment , Volume 2 , Issue 6 , November 1996 , pp. 249 - 257
Copyright
Copyright © The Royal College of Psychiatrists 1996 

References

Borrett, D., Ashby, P., Bilbao, J. et al (1985) Reversible late onset disulfiram-induced neuropathy and encephalopathy. Annals of Neurology, 17, 396–399.Google Scholar
Chick, J. (1995) Acamprosate as an aid in the treatment of alcoholism. Alcohol and Alcoholism, 30, 785–787.Google Scholar
Chick, J., Gough, K., Falkowski, W. et al (1992) Disulfiram treatment of alcoholism. British Journal of Psychiatry, 161, 84–89.CrossRefGoogle ScholarPubMed
Cook, C. (1994) Aetiology of alcohol misuse. In Seminars in Alcohol and Drug Misuse (eds Chick, J. & Cantwell, R.) pp. 94–125. London: Gaskell.Google Scholar
Cutting, J. (1978) A re-appraisal of alcoholic psychoses. Psychological Medicine, 8, 285–295.CrossRefGoogle Scholar
Doty, P. & de Wit, H. (1995) Effects of naltrexone pretreatment on the subjective and performance effects of ethanol in social drinkers. Behavioural Pharmacology, 6, 386–394.Google Scholar
Gianoulakis, C., Krishnan, B. & Thavundayil, J. (1996) Enhanced sensitivity of pituitary β-endorphin to ethanol in subjects at high risk of alcoholism. Archives of General Psychiatry, 53, 250–257.Google Scholar
Greenberg, R. P., Bornstein, R. F., Zborowski, M. J. et al (1994) A meta-analysis of fluoxetine outcome in the treatment of depression. Journal of Nervous and Mental Diseases, 182, 547–551.Google Scholar
Kranzler, H. R., Burleson, J. A., Boca, F. K. et al (1994) Buspirone treatment of anxious alcoholics. Archives of General Psychiatry, 51, 720–731.Google Scholar
Littleton, J. (1995) Acamprosate in alcohol dependence: how does it work? Addiction, 90, 1179–1188.Google Scholar
Malcolm, R., Anton, R. F., Randall, C. L. et al (1992) A placebo-controlled study of busprione in anxious in-patient alcoholics. Alcoholism: Clinical and Experimental Research, 16, 1007–1013.Google Scholar
Mason, B. J., Ritro, F. C., Morgan, R. O. et al (1994) A double-blind placebo-controlled study to evaluate the efficacy and safety of oral nalmefene HCl for alcohol dependence. Alcoholism: Clinical and Experimental Research, 18, 1162–1167.Google Scholar
Nutt, D. (1996) Addiction: brain mechanisms and their treatment implications. Lancet, 347, 31–36.Google Scholar
Paille, F. M., Guelfi, J. D., Perkins, A. C. et al (1995) Randomised multicentre trial of acamprosate in a maintenance programme of abstinence after alcohol detoxification. Alcohol and Alcoholism, 30, 239–247.Google Scholar
Sass, H., Soyka, M., Mann, K. et al (1996) Relapse prevention by acamprosate: results from a placebo controlled study in alcohol dependence. Archives of General Psychiatry, 53, 673–680.Google Scholar
Shaw, G. K. (1995) Detoxification: the use of benzodiazepines. Alcohol and Alcoholism, 30, 765–770.Google Scholar
Volpicelli, J. R. (1995) Naltrexone in alcohol dependence. Lancet, 346, 456.CrossRefGoogle ScholarPubMed
Volpicelli, J. R., Volpicelli, L. A. & O'Brien, C. P. (1995) Medical management of alcohol dependence: clinical use and limitations of naltrexone treatment. Alcohol and Alcoholism, 30, 789–798.Google Scholar
Whitworth, A. B., Fischer, F., Lesch, O. et al (1996) Comparison of acamprosate and placebo in long-term treatment of alcohol dependence. Lancet, 347, 1438–1442.Google Scholar
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