Hostname: page-component-586b7cd67f-t7czq Total loading time: 0 Render date: 2024-11-24T13:04:50.675Z Has data issue: false hasContentIssue false

Stochastic and deterministic analysis of SIS household epidemics

Published online by Cambridge University Press:  08 September 2016

Peter Neal*
Affiliation:
University of Manchester
*
Postal address: School of Mathematics, University of Manchester, Sackville Street, Manchester M60 1QD, UK. Email address: [email protected]
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

We analyse SIS epidemics among populations partitioned into households. The analysis considers both the stochastic and deterministic models and, unlike in previous analyses, we consider general infectious period distributions. For the deterministic model, we prove the existence of an endemic equilibrium for the epidemic if and only if the threshold parameter, R*, is greater than 1. Furthermore, by utilising Markov chains we show that the total number of infectives converges to the endemic equilibrium as t → ∞. For the stochastic model, we prove a law of large numbers result for the convergence, to the deterministic limit, of the mean number of infectives per household. This is followed by the derivation of a Gaussian limit process for the fluctuations of the stochastic model.

Type
General Applied Probability
Copyright
Copyright © Applied Probability Trust 2006 

References

Ball, F. (1999). Stochastic and deterministic models for SIS epidemics among a population partitioned into households. Math. Biosci. 156, 4167.CrossRefGoogle ScholarPubMed
Ball, F. and Lyne, O. D. (2001). Stochastic multitype SIR epidemics among a population partitioned into households. Adv. Appl. Prob. 33, 99123.CrossRefGoogle Scholar
Ball, F. and Neal, P. (2002). A general model for stochastic SIR epidemics with two levels of mixing. Math. Biosci. 180, 73102.Google Scholar
Ball, F., Mollison, D. and Scalia-Tomba, G. (1997). Epidemics with two levels of mixing. Ann. Appl. Prob. 7, 4689.Google Scholar
Barbour, A. D. and Pugliese, A. (2005). Asymptotic behavior of a metapopulation model. Ann. Appl. Prob. 15, 13061338.Google Scholar
Becker, N. G. and Dietz, K. (1995). The effect of household distribution on transmission and control of highly infectious diseases. Math. Biosci. 127, 207219.CrossRefGoogle ScholarPubMed
Billingsley, P. (1968). Convergence of Probability Measures. John Wiley, New York.Google Scholar
Billingsley, P. (1979). Probability and Measure. John Wiley, New York.Google Scholar
Clancy, D. and Pollett, P. K. (2003). A note on quasi-stationary distributions of birth–death processes and the SIS logistic epidemic. J. Appl. Prob. 40, 821825.Google Scholar
Ghoshal, G., Sander, L. M. and Sokolov, I. M. (2004). SIS epidemics with household structure: the self-consistent field method. Math. Biosci. 190, 7185.CrossRefGoogle ScholarPubMed
Kryscio, R. J. and Lefèvre, C. (1989). On the extinction of the S-I-S stochastic logistic epidemic. J. Appl. Prob. 26, 685694.Google Scholar
Kurtz, T. G. (1970). Solutions of ordinary differential equations as limits of pure Jump Markov processes. J. Appl. Prob. 7, 4958.Google Scholar
Kurtz, T. G. (1971). Limit theorems for sequences of Jump Markov processes approximating ordinary differential processes. J. Appl. Prob. 8, 344356.Google Scholar
Neal, P. (2006). Multitype randomised Reed–Frost epidemics and epidemics upon random graphs. Ann. Appl. Prob. 16, 11661189.Google Scholar
Rogers, L. C. G. and Williams, D. (1994). Diffusions, Markov Processes and Martingales, Vol. 1, Foundations, 2nd edn. John Wiley, Chichester.Google Scholar
Ross, R. (1915). Some a priori pathometric equations. British Med. J. 1, 546547.Google Scholar
Solomon, W. (1987). Representation and approximation of large population age distributions using Poisson random measures. Stoch. Process. Appl. 26, 237255.Google Scholar