Hostname: page-component-cd9895bd7-7cvxr Total loading time: 0 Render date: 2024-12-26T20:24:12.916Z Has data issue: false hasContentIssue false
  • English
  • Français

Simulating samples from a genetic population

Published online by Cambridge University Press:  01 July 2016

G. A. Watterson
G. A. Watterson*
Affiliation:
Monash University, Clayton, Victoria
Get access Rights & Permissions [Opens in a new window]

Extract

Consider a genetic population evolving in time. In particular, suppose that the population is very large, that there is a large number of genetic types (alleles) possible for the genes making up the population, and that the numbers of the various alleles change stochastically in time, subject to Mendel's law of inheritance. Assume that there are no selective differences among the genotypes, but that mutation may occur among the alleles.

Type
Research Article
Information
Advances in Applied Probability , Volume 10 , Issue 4 , December 1978 , pp. 720 - 723
Copyright
Copyright © Applied Probability Trust 1978 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Ewens, W. J. (1972) The sampling theory of selectively neutral alleles. Theoret. Popn. Biol. 3, 87–112.Google Scholar
Fuerst, P. A., Chakraborty, R. and Nei, N. (1977) Statistical studies on protein polymorphism in natural populations. Genetics 86, 455–483.Google Scholar
Kirby, K. (1975) A discussion of simulation results for various aspects of the neutral allele model. Theoret. Popn. Biol. 7, 277–287.CrossRefGoogle Scholar
Watterson, G. A. (1978) The homozygosity test of neutrality. Genetics 88, 405–417.Google Scholar