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The sampling theory of selectively neutral alleles

Published online by Cambridge University Press:  01 July 2016

G. A. Watterson
G. A. Watterson*
Affiliation:
Monash University
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Abstract

In a paper of the same title, Ewens has considered the problem of inferring whether the genotypic frequencies observed in a small sample are consistent with a particular population model, in which all types are selectively neutral. The present paper gives the general theory of such sampling schemes, when the sampling is from either a deterministic, or a stochastically varying, population.

The theory is illustrated on a population model which was introduced by Karlin and McGregor. Various results are proved for both the population, and its sample. It is shown that Ewens' sampling theory applies to this population model, and conjectures as to why different population models may have the same sampling theory are made.

Keywords

SAMPLING OF TYPESOCCUPANCY PROBLEMGENETIC POPULATION MODELSESTIMATIONGOODNESS OF FITSELECTIVE NEUTRALITY HYPOTHESIS
Type
Research Article
Information
Advances in Applied Probability , Volume 6 , Issue 3 , September 1974 , pp. 463 - 488
Copyright
Copyright © Applied Probability Trust 1974 

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