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Visuospatial memory improvement in patients with diffuse axonal injury (DAI): a 1-year follow-up study

Published online by Cambridge University Press:  11 October 2016

Ana Luiza Zaninotto ,
Jessica Elias Vicentini ,
Davi Jorge Fontoura Solla ,
Tatiana Tateishi Silva ,
Vinicius Monteiro de Paula Guirado ,
Fabrício Feltrin ,
Mara Cristina Souza de Lucia ,
Manoel Jacobsen Teixeira  and
Wellingson Silva Paiva
Ana Luiza Zaninotto
Affiliation:
Division of Psychology, Clinics Hospital, University of Sao Paulo Medical School, Sao Paulo, Brazil Division of Neurosurgery, Clinics Hospital, University of Sao Paulo Medical School, Sao Paulo, Brazil
Jessica Elias Vicentini
Affiliation:
Division of Psychology, Clinics Hospital, University of Sao Paulo Medical School, Sao Paulo, Brazil
Davi Jorge Fontoura Solla
Affiliation:
Division of Neurosurgery, Clinics Hospital, University of Sao Paulo Medical School, Sao Paulo, Brazil
Tatiana Tateishi Silva
Affiliation:
Division of Psychology, Clinics Hospital, University of Sao Paulo Medical School, Sao Paulo, Brazil
Vinicius Monteiro de Paula Guirado
Affiliation:
Division of Neurosurgery, Clinics Hospital, University of Sao Paulo Medical School, Sao Paulo, Brazil
Fabrício Feltrin
Affiliation:
Institute of Radiology, Clinics Hospital, University of Sao Paulo Medical School, Sao Paulo, Brazil
Mara Cristina Souza de Lucia
Affiliation:
Division of Psychology, Clinics Hospital, University of Sao Paulo Medical School, Sao Paulo, Brazil
Manoel Jacobsen Teixeira
Affiliation:
Division of Neurosurgery, Clinics Hospital, University of Sao Paulo Medical School, Sao Paulo, Brazil
Wellingson Silva Paiva*
Affiliation:
Division of Neurosurgery, Clinics Hospital, University of Sao Paulo Medical School, Sao Paulo, Brazil
*
Wellingson Silva Paiva, 255 Eneas de Carvalho Aguiar st, office 4079, 05403-010, Sao Paulo, SP, Brazil. Tel: +55 112 661 7226; Fax: +55 112 548 6906; E-mail: [email protected]
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Abstract

Objective

Diffuse axonal injury (DAI) is prevalent in traumatic brain injury (TBI), and is often associated with poor outcomes and cognitive impairment, including memory deficits. Few studies have explored visual memory after TBI and its relationship to executive functioning. Executive functioning is crucial for remembering an object’s location, operating devices, driving, and route finding. We compared visual memory performance via the Rey–Osterrieth Complex Figure (ROCF) test 6 and 12 months after DAI.

Method

In total, 40 patients (mean age 28.7 years; 87.5% male) with moderate-to-severe DAI following a road traffic accident completed the 1-year follow-up. There was a three-phase prospective assessment. In phase 1 (1–3 months after trauma), patients completed the Beck Depression Inventory (BDI) and State-Trait Anxiety Inventory (STAI). In phases 2 (6 months) and 3 (12 months), they completed the BDI, STAI, and a neuropsychological battery [ROCF copy and recall, digit span forward/backward, Grooved Pegboard test, intelligence quotient (IQ) by Wechsler Adult Intelligence Scale-III (WAIS-III)].

Results

There was an improvement in ROCF recall over time (p=0.013), but not ROCF copy (p=0.657).There was no change in executive function (Savage scores) copy (p=0.230) or recall (p=0.155). Age, years of education, severity of the trauma, and IQ did not influence ROCF recall improvement.

Conclusion

There are time-dependent improvements in visual memory in patients with DAI. Neuroplasticity in the 1st months after trauma provides an opportunity for visuospatial memory learning. The present findings may be useful to formulate management plans for long-term TBI rehabilitation.

Keywords

cognitionimprovementprogmostictraumatic brain injuryvisuospatial memory
Type
Original Articles
Information
Acta Neuropsychiatrica , Volume 29 , Issue 1 , February 2017 , pp. 35 - 42
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Copyright
© Scandinavian College of Neuropsychopharmacology 2016 

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