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Risperidone in the treatment of psychosis; a concise review
Published online by Cambridge University Press: 18 September 2015
Summary
Risperidone (Risperdal®) is a recently developed antipsychotic drug with the combination of serotonin-5HT2A-and dopamine-D2-antagonism (SDA). In patients with schizophrenia, risperidone reduces positive symptoms at least equally effective as haloperidol, however, risperidone has a reduced propensity for the induction of extrapyramidal symptoms.
In addition, available evidence indicates that risperidone may be an effective treatment for negative symptoms. The optimum daily dose range is between 4 and 8 mgfor most patients. In this review article, risperidone is compared with some other (classical and atypical) neuroleptics. In addition, the pharmacological and pharmacokinetic properties of risperidone are reviewed.
Keywords
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- Research Article
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- Copyright
- Copyright © Scandinavian College of Neuropsychopharmacology 1995
Footnotes
In België zijn risperidon en clozapine nog niet als geneesmiddel geregistreerd.
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