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Risperidone in the treatment of psychosis; a concise review

Published online by Cambridge University Press:  18 September 2015

Summary

Risperidone (Risperdal®) is a recently developed antipsychotic drug with the combination of serotonin-5HT2A-and dopamine-D2-antagonism (SDA). In patients with schizophrenia, risperidone reduces positive symptoms at least equally effective as haloperidol, however, risperidone has a reduced propensity for the induction of extrapyramidal symptoms.

In addition, available evidence indicates that risperidone may be an effective treatment for negative symptoms. The optimum daily dose range is between 4 and 8 mgfor most patients. In this review article, risperidone is compared with some other (classical and atypical) neuroleptics. In addition, the pharmacological and pharmacokinetic properties of risperidone are reviewed.

Type
Research Article
Copyright
Copyright © Scandinavian College of Neuropsychopharmacology 1995

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Footnotes

*

In België zijn risperidon en clozapine nog niet als geneesmiddel geregistreerd.

References

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