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Long-term depression is a stroke risk factor

Published online by Cambridge University Press:  24 June 2014

Emel Kocer ,
Abdulkadir Kocer ,
Yıldız Degirmenci  and
Mehmet Eryılmaz
Emel Kocer*
Affiliation:
Psychiatry Department, Medical Faculty, Bezmialem Vakif University, Istanbul, Turkey
Abdulkadir Kocer
Affiliation:
Neurology Department, Medical Faculty, Bezmialem Vakif University, Istanbul, Turkey
Yıldız Degirmenci
Affiliation:
Neurology Department, Düzce Medical Faculty, Düzce University, Duzce, Turkey
Mehmet Eryılmaz
Affiliation:
Neurology Department, Düzce Medical Faculty, Düzce University, Duzce, Turkey
*
Assistant Professor Emel Koçer, Psychiatry Department, Medical Faculty, Bezmialem Vakif University, Fatih, Istanbul, Turkey. Tel: +90 505 426 28 28; Fax: +90 212 453 17 17; E-mail: [email protected]
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Extract

Kocer E, Kocer A, Degirmenci Y, Eryılmaz M. Long-term depression is a stroke risk factor.

Background and Aim: Only a few studies have evaluated depression prevalence in pre-stroke period in comparison to controls. We investigated this association based on a hospitalised stroke population.

Methods: One hundred and forty-eight stroke patients were evaluated. The presence of depression was compared with those of 100 healthy controls without stroke, from the same region. Depression was accepted as present or not present after history and clinical evaluation according to Diagnostic and Statistical Manual of Mental Disorders-IV. Socio-demographic variables, other stroke risk factors and the time of diagnosis of depression (how many year or month they got depression) were recorded.

Results: Gender and mean age of patients and controls were similar in comparison. Depression was diagnosed in 27 patients and 24 controls (p > 0.05). The time period passed after diagnosis of depression was longer in stroke patients in comparison to controls (p < 0.001).

Conclusions: The risk of stroke should be considered in elderly with long-term depression. This indicates that treatment of depression is another factor which should be considered in prevention of brain stroke.

Keywords

depressionlong-term depressionrisk factorstrokestroke prevention
Type
Research Article
Information
Acta Neuropsychiatrica , Volume 23 , Issue 6 , December 2011 , pp. 292 - 296
Copyright
Copyright © Cambridge University Press 2011

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References

1.Evans, DL, Charney, DS, Lewis, L et al. Mood disorders in the medically ill: scientific review and recommendations. Biol Psychiatry 2005;58:175–189.CrossRefGoogle Scholar
2.Carod Artal, FJ.Post-stroke depression (I). Epidemiology, diagnostic criteria and risk factors. Rev Neurol 2006;42:169–175.Google ScholarPubMed
3.Krishnan, KR.Depression as a contributing factor in cerebrovascular disease. Am Heart J 2000;140:70–76.CrossRefGoogle ScholarPubMed
4.Jonas, BS, Mussolino, ME.Symptoms of depression as a prospective riskfactor for stroke. Psychosom Med 2000;62:463–471.CrossRefGoogle Scholar
5.Davidson, K, Jonas, BS, Dixon, KE, Markovitz, JH.Do depression symptoms predict early hypertension incidence in young adults in the CARDIA study? Arch Intern Med 2000;160:1495–1500.CrossRefGoogle ScholarPubMed
6.Penninx, BWJH, Beekman, ATF, Honig, A et al. Depression and cardiac mortality: results from a community-based longitudinal study. Arch Gen Psychiatry 2001;58:221–227.CrossRefGoogle ScholarPubMed
7.Gump, BB, Matthews, KA, Eberly, LE, Chang, YF; for the MRFIT Research Group. Depressive symptoms and mortality in men: results from the Multiple Risk Factor Intervention Trial. Stroke 2005;36:98–102.CrossRefGoogle ScholarPubMed
8.Carod-Artal, FJ, Egido, JA.Quality of life after stroke: the importance of a good recovery. Cerebrovasc Dis 2009;27:204–214.CrossRefGoogle ScholarPubMed
9.Larson, SL, Owens, PL, Ford, D, Eaton, W.Depressive disorder, dysthymia, and risk of stroke: thirteen-year follow-up from the Baltimore Epidemiologic Catchment Area study. Stroke 2001;32:1979–1983.CrossRefGoogle ScholarPubMed
10.Ohira, T, Iso, HSatoh, S et al. Prospective study of depressive symptoms and risk of stroke among Japanese. Stroke 2001;32:903–908.CrossRefGoogle ScholarPubMed
11.Salaycik, KJ, Kelly-Hayes, M, Beiser, A et al. Depressive symptoms and risk of stroke: the Framingham Study. Stroke 2007;38:16–21.CrossRefGoogle ScholarPubMed
12.Musselman, DL, Evans, DL, Nemeroff, CB.The relationship of depression to cardiovascular disease: epidemiology, biology, and treatment. Arch Gen Psychiatry 1998;55:580–592.CrossRefGoogle ScholarPubMed
13.Jiang, W, Krishnan, RRK, O'Connor, CM.Depression and heart disease: evidence of a link, and its therapeutic implications. CNS Drugs 2002;16:111–127.CrossRefGoogle ScholarPubMed
14.Ladwig, KH, Marten-Mittag, B, Lowel, H, Doring, A, Koenig, W.C-reactive protein, depressed mood, and the prediction of coronary heart disease in initially healthy men: results from the MONICA-KORA Augsburg Cohort Study 1984–1998. Eur Heart J 2005;26:2537–2542.CrossRefGoogle ScholarPubMed
15.Empana, JP, Sykes, DH, Luc, G et al. Contributions of depressive mood and circulating inflammatory markers to coronary heart disease in healthy European men: the Prospective Epidemiological Study of Myocardial Infarction (PRIME). Circulation 2005;111:2299–2305.CrossRefGoogle ScholarPubMed
16.Williams, L.Depression and stroke: cause or consequence? Semin Neurol 2005;25:396–409.CrossRefGoogle ScholarPubMed
17.Serebruany, VL, Glassman, AH, Malinin, AI et al. Platelet/endothelial biomarkers in depressed patients treated with the selective serotonin reuptake inhibitor sertraline after acute coronary events: the Sertraline AntiDepressant Heart Attack Randomized Trial (SADHART) Platelet substudy. Circulation 2003;108:939–944.CrossRefGoogle ScholarPubMed
18.Ataoglu, A, Canan, F.Mean platelet volume in patients with major depression: effect of escitalopram treatment. J Clin Psychopharmacol 2009;29:368–371.CrossRefGoogle ScholarPubMed
19.Wannamethee, SG, Shaper, AG.Physical activity in the prevention of cardiovascular disease: an epidemiological perspective. Sports Med 2001;31:101–114.CrossRefGoogle ScholarPubMed
20.Fox, KR.The influence of physical activity on mental well-being Public Health Nutr 1999;2:411–418.CrossRefGoogle ScholarPubMed
21.Weyerer, S.Physical inactivity and depression in the community. Evidence from the Upper Bavarian Field Study. Int J Sports Med 1992;13:492–496.CrossRefGoogle ScholarPubMed
22.Camacho, TC, Roberts, RE, Lazarus, NB, Kaplan, GA, Cohen, RD.Physical activity and depression: evidence from the Alameda County Study. Am J Epidemiol 1991;134: 220–231.CrossRefGoogle ScholarPubMed
23.ÖZkürkçügil, A, Aydemir, Ö, Yıldız, M, Danacı, E, Koroglu, E.Adaptation and reliability study of structured clinical interview for DSM-IV Axis I disorders (Turkish). Turk J Drugs Ther 1999;12:233–236.Google Scholar
24.Diagnostic and statistical manual for mental disorders: DSM-IV, 4th edn. Washington, DC: American Psychiatric Association, 1994.Google Scholar
25.Colantonio, A, Kasi, SV, Ostfeld, AM.Depressive symptoms and other psychosocial factors as predictors of stroke in the elderly. Am J Epidemiol 1992;136:884–894.CrossRefGoogle ScholarPubMed
26.Wassertheil-Smoller, S, Applegate, WB, Berge, K et al. Change in depression as a precursor of cardiovascular events: SHEP Cooperative Research Group (Systolic Hypertension in the elderly). Arch Intern Med 1996;156:553–561.CrossRefGoogle Scholar
27.May, M, McCarron, P, Stansfeld, S et al. Does psychological distress predict the risk of ischemic stroke and transient ischemic attack? The Caerphilly Study. Stroke 2002;33:7–12.CrossRefGoogle ScholarPubMed
28.Everson, SA, Roberts, RE, Goldberg, DE, Kaplan, GA.Depressive symptoms and increased risk of stroke mortality over a 29-year period. Arch Intern Med 1998;158: 1133–1138.CrossRefGoogle Scholar
29.Wu, HQ, Zhang, Y, Li, YS, Zhu, Y, Shen, F.Clinical characteristics of patients with depressive disorders at Department of Neurology in general hospitals. Zhonghua Yi Xue Za Zhi 2010;90:1760–1763.Google ScholarPubMed
30.Carson, AJ, Ringbauer, B, MacKenzie, L, Warlow, C, Sharpe, M.Neurological disease, emotional disorder, and disability: they are related: a study of 300 consecutive new referrals to a neurology outpatient department. J Neurol Neurosurg Psychiatry 2000;68:202–206.CrossRefGoogle ScholarPubMed
31.Hamilton, J, Campos, R, Creed, F.Anxiety, depression and management of medically unexplained symptoms in medical clinics. J R Coll Physicians Lond 1996;30:18–20.Google ScholarPubMed
32.Nilsson, FM, Kessing, LV.Increased risk of developing stroke for patients with major affective disorder: a registry study. Eur Arch Psychiatry Clin Neurosci 2004;254:387–391.CrossRefGoogle ScholarPubMed
33.Surtees, PG, Wainwright, WJ, Luben, RN, Wareham, NJ, Bingham, SA, Khaw, T.Psychological distress, major depressive disorder, and risk of stroke. Neurology 2008;4: 788–794.CrossRefGoogle Scholar