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Influence of Propofol on the Mood - a comparative study

Published online by Cambridge University Press:  18 September 2015

P.J. De Keyzer ,
J. D'haese ,
H.A.H. D'haenen  and
F. Camu
P.J. De Keyzer*
Affiliation:
kliniekhoofd, Dienst Psychiatric AZ, VUB
J. D'haese
Affiliation:
diensthoofd, Dienst anesthesiologie, AZ, VUB
H.A.H. D'haenen
Affiliation:
kliniekhoofd, Dienst Psychiatric AZ, VUB
F. Camu
Affiliation:
diensthoofd, Dienst anesthesiologie, AZ, VUB
*
dienst psychiatrie Academisch Ziekenhuis VUB Laarbeeklaan 101 1090 Brussel, België
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Summary

The influence of propofol on mood was evaluated, considering the potential use of propofol as an anesthetic for electroconvulsive therapy. The mood state of 80 psychologically healthy subjects was assessed before and from 1/2 hour till 4 hours after surgery under anesthesia with either propofol or methohexitone. The mood was assessed with the Profile of Mood States (POMS). The propofol group was more elated from one hour until 4 hours after anesthesia (p<0,01 )(factor 1). 1 hour after anesthesia the propofol group was continuously more composed than the methohexitone group (p<0,01) (factor 4) and after two hours the propofol group was more agreeable (p<0,05) (factor 2). Moreover, patients, who received propofol, were less tired (factor 3) and confused (factor 5). It can be concluded that, compared with methohexitone, propofol has a favorable influence on different aspects of mood.

Keywords

propofolmethohexitonemoodProfile of Mood StatespropofolmethohexitonegemoedstoestandProfile of Mood States
Type
Research Article
Information
Acta Neuropsychiatrica , Volume 3 , Issue 4 , December 1991 , pp. 66 - 69
Copyright
Copyright © Scandinavian College of Neuropsychopharmacology 1991

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References

Literatuur

1.Kay, NH, Uppington, J, Sear, JW, Allen, MC. Use of an emulsion of ICI 35868(propofoI) for the induction and maintenance of anesthesia. Br J Anesth 1985; 57:736–42.CrossRefGoogle Scholar
2.Kay, B, Healy, TEJ. Propofol (Diprivan) for outpatient cystoscopy; efficacy and recovery compared with althesin and methohexitone. Postgr med J 1985; 61:108–14.Google ScholarPubMed
3.Rouse, EC. Propofol for electroconvulsive therapy. Anest 1988; 43(suppl): 61–4.CrossRefGoogle ScholarPubMed
4.Simpson, KH, Halsali, PJ, Carr, CME, Stewart, KG. Seizure duration after methohexitone or propofol for induction of anesthesia for electroconvulsive therapy (ECT). Br J Anesth 1987; 59:1323–4.Google Scholar
5.Maletsky, BM. Seizure duration and clinical effect in elec- trocon-vulsive therapy. Compr Psychiat 1978;19:541–50.CrossRefGoogle Scholar
6.Ottoson, JO. Experimental studies of the mode of action of electroconvulsive therapy. Acta psychiat neurol scand 1960;35(suppl 145):1.Google Scholar
7.Cronholm, B and Ottoson, JO. Experimental studies of the therapeutic action of electroconvulsive therapy in endogenous depressions. Acta psychiat scand 1960; 35(suppl 145):69.CrossRefGoogle Scholar
8.Rich, CI, Black, NA. The efficiency of ECT:II. Correlation of specific treatment variables to response rate in unilateral ECT. Psychiat Res 1985;16:147–54.CrossRefGoogle ScholarPubMed
9.Price, TRP, McAllister, TW. Response of depressed patients to sequential unilateral nondominant brief-pulse and bilateral sinusoidal ECT. J clin Psychiat 1986; 47:182–86.Google ScholarPubMed
10.Sackum, HAet al.Studies of dosage, seizure threshold, and seizure duration in ECT. Biol Psychiat 1987; 22:249–68.CrossRefGoogle Scholar
11.Wuner, RGet al.Effect of electroconvulsive therapy upon brain electrical activity. Ann NY Acad Sci 1986;462:270–81.CrossRefGoogle Scholar
12.Deakin, JFW. Antidepressant effects of electroconvulsive therapyxurrent seizure?(editorial). Br med J 1983;286(1): 1083–4.CrossRefGoogle Scholar
13.McDonald, NJ, Mannion, D, Lee, P, O'Toole, P, O'Boyle, C, Keane, PK. Mood evaluation and outpatient anaesthesia. Anesth 1988; 43 (suppl): 68–9.CrossRefGoogle ScholarPubMed
14.Asberg, M, Montgomery, SA, Perris, C, Schalling, D, Sedvall, G. A comprehensive psychopathological rating scale. Acta psychiat scand 1978 (suppl 271).Google Scholar
15.Lachar, D. The MMPI Clinical Assesment and Automated Interpretation. L.A. West Psychol Serv 1980.Google Scholar
16.McNair, DM, Lorr, M, Droppleman, LF. Profile of Mood States, San Diego Publ Educ Indust Test Serv 1971. (nederlandstalige bewer-king door Daems C, Vrije Universiteit Brussel, 1984).Google Scholar