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Chapter 11 - The Goldilocks Zone

How Do Financial Considerations Influence the Rate and Direction of Drug Development?

from Section 2 - The Financial Determinants of Discovery

Published online by Cambridge University Press:  06 April 2023

Mark P. Khurana
Affiliation:
University of Copenhagen
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Summary

When companies working in the pharmaceutical sector choose to develop new products, they have a certain set of choices. They can decide not to develop anything new, they can choose to make incremental improvements to existing products or choose to create something entirely new. In the short term, firms are also under pressure by shareholders to provide value, which may discourage longer-term investments. This may lead to an affinity for incremental discoveries and pursuits that are more likely to succeed in the short-term, such as me-too drugs. Chapter 11 explores how financial considerations influence the rate and direction of drug development, using antibiotics as a primary case example. Additionally, the chapter explores why there is missing novelty in drug development and how we might stimulate more breakthroughs in the future.

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Chapter
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The Trajectory of Discovery
What Determines the Rate and Direction of Medical Progress?
, pp. 61 - 66
Publisher: Cambridge University Press
Print publication year: 2023

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  • The Goldilocks Zone
  • Mark P. Khurana, University of Copenhagen
  • Book: The Trajectory of Discovery
  • Online publication: 06 April 2023
  • Chapter DOI: https://doi.org/10.1017/9781009354424.012
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  • The Goldilocks Zone
  • Mark P. Khurana, University of Copenhagen
  • Book: The Trajectory of Discovery
  • Online publication: 06 April 2023
  • Chapter DOI: https://doi.org/10.1017/9781009354424.012
Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • The Goldilocks Zone
  • Mark P. Khurana, University of Copenhagen
  • Book: The Trajectory of Discovery
  • Online publication: 06 April 2023
  • Chapter DOI: https://doi.org/10.1017/9781009354424.012
Available formats
×