Published online by Cambridge University Press: 21 June 2019
Alzheimer’s disease (AD) is an irreversible, progressive neuro-degenerative disorder of the brain that affects various aspects of cognitive functions. It manifests as a progressive impairment of day-to-day functioning, eventually leading to a breakdown of even the simplest abilities. It is the commonest cause of dementia in the world. It is a major cause of disability, dependency and carer stress among older people. It places an immense burden on society and is one of the top 10 causes of mortality worldwide [1].
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