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Chapter 14 - Drugs to Treat Dementia

from Part 2 - Psychopharmacology of the Main Psychotropic Drug Groups

Published online by Cambridge University Press:  29 May 2020

By
Ross Dunne  and
Alistair Burns
Edited by
Peter M. Haddad  and
David J. Nutt
Peter M. Haddad
Affiliation:
Hamad Medical Corporation, Qatar
David J. Nutt
Affiliation:
Centre for Neuropsychopharmacology, Division of Psychiatry, Department of Brain Sciences, Imperial College London
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Summary

Dementia is a clinical syndrome that is estimated to affect 46 million people worldwide. This number is estimated to increase to 131.5 million by 2050 (Prince et al., 2015). Dementia has a huge impact on people with the condition, their families and on health and social services. In the UK alone, it affects some 850 000 people with an estimated annual cost of £26 billion. It is a progressive neuropsychiatric condition leading to a significant strain on individuals, their families and the wider society. The risk increases with age and the burden of disease is set to rise in the coming years (Prince et al., 2015). While symptomatic treatments for the commonest cause of dementia, Alzheimer’s disease, are available, no disease-modifying therapy has emerged and the majority of trials in this space have been negative although there is room for optimism (Aisen, 2017).

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Seminars in Clinical Psychopharmacology , pp. 433 - 453
Publisher: Cambridge University Press
Print publication year: 2020

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