Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-586b7cd67f-2plfb Total loading time: 0 Render date: 2024-11-30T23:33:47.920Z Has data issue: false hasContentIssue false

Section 2 - Gastrointestinal System

from Part 3 - Systems Based Overview of Cancer Complications

Published online by Cambridge University Press:  10 August 2023

Monica Kathleen Wattana
Monica Kathleen Wattana
Affiliation:
University of Texas, MD Anderson Cancer Center
Get access

Summary

Overview of gastrointestinal complications including constipation, diarrhea, nausea, and vomiting, feeding tube complications, bowel perforation and obstruction, and neutropenic enterocolitis

Keywords

constipationdiarrheanauseavomitingbowel obstructionmesenteric ischemiatyphlitismucositis
Type
Chapter
Information
Pocket Guide to Oncologic Emergencies , pp. 97 - 142
Publisher: Cambridge University Press
Print publication year: 2023

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

References

Dzierżanowski, T, Larkin, P. Proposed criteria for constipation in palliative care patients. A multicenter cohort study. Journal of Clinical Medicine. 2020 Dec 25; 10(1): 40. Doi: 10.3390/jcm10010040.CrossRefGoogle ScholarPubMed
Dzierżanowski, T, Mercadante, S. Constipation in cancer patients – An update of clinical evidence. Current Treatment Options in Oncology. 2022 Apr 20;23: 936‒950. Doi: 10.1007/s11864-022-00976-y.CrossRefGoogle Scholar
Wickham, RJ. Managing constipation in adults with cancer. Journal of the Advanced Practitioner in Oncology. 2017;8(2):149–161.Google ScholarPubMed

References

Benson, AB III, Ajani, JA, Catalano, RB, Engelking, C, Kornblau, SM, Martenson, JA, McCallum, R, Mitchell, EP, O’Dorisio, TM, Vokes, EE, Wadler, S. Recommended guidelines for the treatment of cancer treatment-induced diarrhea. Journal of Clinical Oncology. 2004; 22(14):2918‒2926.CrossRefGoogle ScholarPubMed
Ferrer Pérez Jr, A, Vidal, M, Serrano, Solares S, Tobeña, Puyal M. Evaluation of nausea, vomiting, and diarrhea in oncologic patients at the emergency department. Journal of Clinical Oncology. 2009;27(15) suppl: e20727. Doi: 10.1200/JCO.2004.04.132.CrossRefGoogle Scholar
Kornblau, S. Benson, AB, Catalano, R, Champlin, RE, Engelking, C, Field, M, Ippoliti, C, Lazarus, HM, Mitchell, E, Rubin, J, Stiff, PJ, Vokes, E, Wadler, S. Management of cancer treatment-related diarrhea. Issues and therapeutic strategies. Journal of Pain and Symptom Management. 2000;19(2):118‒129. Doi: 10.1016/s0885–3924(99)00149-9.CrossRefGoogle ScholarPubMed

References

MD Anderson Cancer Center Adult Antiemetic Management of Chemotherapy-Induced Nausea and Vomiting (CINV) Guidelines. Retrieved from www.mdanderson.org/content/dam/mdanderson/documents/forphysicians/algorithms/clin cal-management/clin-management-cinv-adult-web-algorithm.pdfGoogle Scholar
Navari, RM. Treatment of breakthrough and refractory chemotherapy-induced nausea and vomiting. BioMed Research International. 2015;1‒6: Article ID 595894.CrossRefGoogle Scholar
Rao, KV, Faso, A. Chemotherapy-induced nausea and vomiting: Optimizing prevention and management. American Health & Drug Benefits. 2012;5(4):232–240.Google ScholarPubMed
Tilleman, JA, Pick, A, DeSimone, EM, Price, S, Runia-Bade, L. Chemotherapy-induced nausea and vomiting. US Pharmacist. 2018; 43(2) (Specialty&Oncology suppl):2‒5.Google Scholar

References

Baskin, WN. Acute complications associated with bedside placement of feeding tubes. Nutrition in Clinical Practice. 2006 Feb;21(1):40‒55. Doi: 10.1177/011542650602100140. PMID: 16439769.CrossRefGoogle ScholarPubMed
Blumenstein, I, Shastri, YM, Stein, J. Gastroenteric tube feeding: Techniques, problems and solutions. World Journal of Gastroenterology. 2014 Jul 14;20(26):8505‒8524. Doi: 10.3748/wjg.v20.i26.8505. PMID: 25024606; PMCID: PMC4093701.CrossRefGoogle ScholarPubMed

References

Fejleh, MP, Chang, M, Anand, G, Savides, TJ. Use of a large-diameter 30-French venting gastrostomy tube is effective and safe for symptom palliation in patients with malignant bowel obstruction. Annals of Gastroenterology 2022; 35(2):177‒181. Doi: 10.20524/aog.2022.0694.Google ScholarPubMed
Franke, AJ, Iqbal, A, Starr, JS, Nair, RM, George, Jr TJ. Management of malignant bowel obstruction associated with GI cancers. Journal of Oncology Practice 2017;13(7):426‒434. Doi: 10.1200/JOP.2017.022210.CrossRefGoogle ScholarPubMed
Ledet, CR, Santos, D. Acute abdomen in cancer patients. In: Nates, J, Price, K (eds.) Oncologic Critical Care. 2020:847‒856, Springer, Cham. Doi: 10.1007/978-3-319-74588-6_75.CrossRefGoogle Scholar
Roeland, EJ. Managing malignant bowel obstruction: Moving beyond drip and suck. Journal of Oncology Practice. 2017;13(7):437‒438. Doi: 10.1200/JOP.2017.024596.CrossRefGoogle ScholarPubMed
Tuca, A, Guell, E, Martinez-Losada, E, Codorniu, N. Malignant bowel obstruction in advanced cancer patients: Epidemiology, management, and factors influencing spontaneous resolution. Cancer Management and Research. 2012; 4:159–169. Doi: 10.2147/CMAR.S29297.CrossRefGoogle ScholarPubMed
Veld, JV, Amelung, FJ, Consten, ECJ, van Hooft, JE, Tanis, PJ. Behandeling van linkszijdig obstructief coloncarcinoom [Treatment of left-sided obstructive colon cancer]. Nederlands Tijdschrift voor Geneeskunde. 2022 Feb 16;166: D6370.Google Scholar

References

Abu-Hejleh, T, Mezhir, JJ, Goodheart, MJ, Halfdanarson, TR. Incidence and management of gastrointestinal perforation from bevacizumab in advanced cancers. Current Oncology Reports. 2012;14(4):277‒284. Doi: 10.1007/s11912-012-0238-8.CrossRefGoogle ScholarPubMed
Kass, SL, Linden, AF, Jackson, PG, De Brito, PA, Atkins, MB. Bowel perforation associated with robust response to BRAF/MEK inhibitor therapy for BRAF-mutant melanoma: A case report. Melanoma Management. 2015;2(2):115‒120. Doi: 10.2217/mmt.15.10.CrossRefGoogle ScholarPubMed
Kim, SW, Kim, HC, Yang, DM. Perforated tumours in the gastrointestinal tract: CT findings and clinical implications. The British Journal of Radiology. 2012;85(1017):1307–1313. Doi: 10.1259/bjr/21382039.CrossRefGoogle ScholarPubMed
Ledet, CR, Santos, D. Acute abdomen in cancer patients. Oncologic Critical Care. 2019;847‒856. Springer International Publishing. Doi: 10.1007/978-3-319-74588-6_75.Google Scholar
Otani, K, Kawai, K, Hata, K, Tanaka, T, Nishikawa, T, Sasaki, K, Kaneko, M, Murono, K, Emoto, S, Nozawa, H. Colon cancer with perforation. Surgery Today 2019;49(1):15‒20. Doi: 10.1007/s00595-018-1661-8.CrossRefGoogle ScholarPubMed
Yeung, SCJ, Escalante, CP. Other oncologic emergencies. In: Kufe, DW, Pollock, RE, Weichselbaum, RR, Bast, RC, Gansler, TS, Holland, JF, Frei, E (eds.), Holland-Frei Cancer Medicine. 6th edition, 2003. BC Decker, Hamilton (ON). Available from: www.ncbi.nlm.nih.gov/books/NBK13526/Google Scholar

References

Bala, M, Kashuk, J, Moore, EE, Kluger, Y, Biffl, W, Gomes, CA, Ben-Ishay, O, Rubinstein, C, Balogh, ZJ, Civil, I, Coccolini, F, Leppaniemi, A, Peitzman, A, Ansaloni, L, Sugrue, M, Sartelli, M, Di, Saverio S, Fraga, GP, Catena, F. Acute mesenteric ischemia: Guidelines of the World Society of Emergency Surgery. World Journal of Emergency Surgery. 2017;12:38. PMID: 28794797. www.ncbi.nlm.nih.gov/pubmed/28794797CrossRefGoogle ScholarPubMed
Caine, GJ, Stonelake, PS, Lip, GY, Kehoe, ST. The hypercoagulable state of malignancy: Pathogenesis and current debate. Neoplasia. 2002;4(6):465–473. Doi: 10.1038/sj.neo.7900263.CrossRefGoogle ScholarPubMed
Expert Panels on Vascular Imaging and Gastrointestinal Imaging: et al. ACR Appropriateness Criteria® Imaging of Mesenteric Ischemia. Journal of the American College of Radiology. 2018;15(11S):S332‒S340. Doi: 10.1016/j.jacr.2018.09.018.CrossRefGoogle Scholar
Florim, S, Almeida, A, Rocha, D, Portugal, P. Acute mesenteric ischaemia: A pictorial review. Insights into Imaging. 2018;9(5):673–682. Doi: 10.1007/s13244-018-0641-2.CrossRefGoogle ScholarPubMed
Moore, RA, Adel, N, Riedel, E, Bhutani, M, Feldman, DR, Tabbara, NE, Soff, G, Parameswaran, R, Hassoun, H. High incidence of thromboembolic events in patients treated with cisplatin-based chemotherapy: A large retrospective analysis. Journal of Clinical Oncology. 2011;29(25):3466–3473. Doi:10.1200/JCO.2011.35.5669.CrossRefGoogle ScholarPubMed
Oldenburg, WA, Lau, LL, Rodenberg, TJ, Edmonds, HJ, Burger, CD. Acute mesenteric ischemia: A clinical review. Archives of Internal Medicine. 2004;164(10):1054–1062. Doi: 10.1001/archinte.164.10.1054.CrossRefGoogle ScholarPubMed
Patel, S. Mesenteric ischemia. Case study, SAEM. 2019. www.saem.org/about-saem/academies-interest-groups-affiliates2/cdem/for-students/online-education/m4-curriculum/group-m4-gastrointestinal/mesenteric-ischemiaGoogle Scholar
Reginelli, A, Sangiovanni, A, Vacca, G, Belfiore, MP, Pignatiello, M, Viscardi, G, Clemente, A, Urraro, F, Cappabianca, S. Chemotherapy-induced bowel ischemia: Diagnostic imaging overview. Abdominal Radiology. 2022;47:1556–1564. Doi: 10.1007/s00261–021-03024-9.CrossRefGoogle ScholarPubMed

References

Bowen, J, Wardill, H. The science of mucositis. Support Care Cancer. 2022 Apr;30(4):2915–2917. Doi: 10.1007/s00520-022-06840-x. Epub 2022 Jan 24. PMID: 35067733.CrossRefGoogle ScholarPubMed
Elad, S, Cheng, KKF, Lalla, RV, Yarom, N, Hong, C, Logan, RM, Bowen, J, Gibson, R, Saunders, DP, Zadik, Y, Ariyawardana, A, Correa, ME, Ranna, V, Bossi, P; Mucositis Guidelines Leadership Group of the Multinational Association of Supportive Care in Cancer and International Society of Oral Oncology (MASCC/ISOO). MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy. Cancer. 2020 Oct 1;126(19):4423–4431. Doi: 10.1002/cncr.33100. Epub 2020 Jul 28. Erratum in: Cancer. 2021 Oct 1;127(19):3700. PMID: 32786044; PMCID: PMC7540329.CrossRefGoogle ScholarPubMed
Erowele, G, Ndefo, U. Oral mucositis: Update on prevention and management strategies. US Pharmacist. 2009;34(1)(Oncology suppl.):10–14.Google Scholar
McGuire, DB, Fulton, JS, Park, J, Brown, CG, Correa, ME, Eilers, J, Elad, S, Gibson, F, Oberle-Edwards, LK, Bowen, J, Lalla, RV; Mucositis Study Group of the Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology (MASCC/ISOO). Systematic review of basic oral care for the management of oral mucositis in cancer patients. Support Care Cancer. 2013;21 :3165–3177. Doi: 10.1007/s00520-013-1942–0.CrossRefGoogle ScholarPubMed
Sarvizadeh, M, Hemati, S, Meidani, M, Ashouri, M, Roayaei, M, Shahsanai, A. Morphine mouthwash for the management of oral mucositis in patients with head and neck cancer. Advanced Biomedical Research. 2015 Feb 11;4(44). Doi: 10.4103/2277-9175.151254.Google ScholarPubMed
Wardill, HR, Bowen, JM, Gibson, RJ. New pharmacotherapy options for chemotherapy-induced alimentary mucositis. Expert Opinion on Biological Therapy 2014 Mar;14(3):347–354. Doi: 10.1517/14712598.2014.874412. Epub 2014 Jan 6. PMID: 24387716.CrossRefGoogle ScholarPubMed

References

Itani, M, Kaur, N, Roychowdhury, A, Mellnick, VM, Lubner, MG, Dasyam, AK, Khanna, L, Prasad, SR, Katabathina, VS. Gastrointestinal manifestations of immunodeficiency: Imaging spectrum. Radiographics: A Review Publication of the Radiological Society of North America, Inc. 2022;42(3):759‒777. Doi: 10.1148/rg.210169.CrossRefGoogle ScholarPubMed
Kapandji, N, Azoulay, E, Zafrani, L. Recent advances in neutropenic enterocolitis: Insights into the role of gut microbiota. Blood Reviews. 2022 Feb 14;100944. Doi: 10.1016/j.blre.2022.100944.CrossRefGoogle Scholar
Ledet, CR, Santos, D. Acute abdomen in cancer patients. In: Nates, J, Price, K (eds), Oncologic Critical Care. 2020 Springer, Cham. Doi: 10.1007/978-3-319-74588-6_75.Google Scholar
Qasim, A, Nahas, J. Neutropenic Enterocolitis (Typhlitis) [Updated 2021 Aug 11]. In: StatPearls [Internet]. 2022 StatPearls Publishing, Treasure Island, FL. Available at: www.ncbi.nlm.nih.gov/books/NBK551577/Google Scholar
Rodrigues, FG, Dasilva, G, Wexner, SD. Neutropenic enterocolitis. World Journal of Gastroenterology. 2017;23(1):42‒47. Doi: 10.3748/wjg.v23.i1.42.CrossRefGoogle ScholarPubMed

References

Bhutta, BS, Fatima, R, Aziz, M. Radiation enteritis. StatPearls, StatPearls Publishing, Feb 9, 2022. Available from: www.ncbi.nlm.nih.gov/books/NBK526032/Google Scholar
Hale, MF. Radiation enteritis: From diagnosis to management. Current Opinion in Gastroenterology. 2020;36(3):208–214. Doi: 10.1097/MOG.0000000000000632.CrossRefGoogle ScholarPubMed
Harb, AH, Abou, Fadel C, Sharara, AI. Radiation enteritis. Current Gastroenterology Reports. 2014;16(5):383. Doi: 10.1007/s11894-014-0383-3.CrossRefGoogle ScholarPubMed
PDQ Supportive and Palliative Care Editorial Board. Gastrointestinal Complications (PDQ®): Health Professional Version. PDQ Cancer Information Summaries, National Cancer Institute (US), Jan 21, 2022.Google Scholar

References

Faraci, M, Bertaina, A, Luksch, R, Calore, E, Lanino, E, Saglio, F, Prete, A, Menconi, M, De Simone, G, Tintori, V, Cesaro, S, Santarone, S, Orofino, MG, Locatelli, F, Zecca, M. Sinusoidal obstruction syndrome/veno-occlusive disease after autologous or allogeneic hematopoietic stem cell transplantation in children: A retrospective study of the Italian Hematology-Oncology Association–Hematopoietic Stem Cell Transplantation Group. Biology of Blood and Marrow Transplantation. 2019 Feb;25(2):313–320.CrossRefGoogle ScholarPubMed
Nassereddine, S, Alsubait, S, Tabbara, I. Sinusoidal obstruction syndrome (veno-occlusive disease) following hematopoietic stem cell transplant: Insights and therapeutic advances. Anticancer Research. 2018;38(5):2597–2605. Doi: 10.21873/anticanres.12501.Google ScholarPubMed
Roeker, LE, Kim, HT, Glotzbecker, B, Nageshwar, P, Nikiforow, S, Koreth, J, Armand, P, Cutler, C, Alyea, EP, Antin, JH, Richardson, PG, Soiffer, RJ, Ho, VT. Early clinical predictors of hepatic veno-occlusive disease/sinusoidal obstruction syndrome after myeloablative stem cell transplantation. Biology of Blood and Marrow Transplantation. 2019 Jan;25(1):137–144.CrossRefGoogle ScholarPubMed
Valla, D-C, Cazals-Hatem, D. Sinusoidal obstruction syndrome. Clinics and Research in Hepatology and Gastroenterology. 2016 Sep;40(4):378–385.CrossRefGoogle ScholarPubMed

Save book to Kindle

To save this book to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×