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Chapter 3 - Postoperative Cognitive Dysfunction

An Overview

from Section 1 - Cognitive Function in Perioperative Care

Published online by Cambridge University Press:  11 April 2019

Roderic G. Eckenhoff
Affiliation:
University of Pennsylvania
Niccolò Terrando
Affiliation:
Duke University, North Carolina
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Publisher: Cambridge University Press
Print publication year: 2019

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References

Bedford, PD. Adverse cerebral effects of anaesthesia on old people. The Lancet 1955;266:259263.CrossRefGoogle Scholar
Moller, JT, Cluitmans, P, Rasmussen, LS, et al. Long-term postoperative cognitive dysfunction in the elderly ISPOCD1 study. ISPOCD investigators. International Study of Post-Operative Cognitive Dysfunction. The Lancet 1998;351:857861.Google Scholar
Nadelson, MR, Sanders, RD, Avidan, MS. Perioperative cognitive trajectory in adults. British Journal of Anaesthesiology 2014;112:440451.CrossRefGoogle ScholarPubMed
Dijkstra, JB, Jolles, J. Postoperative cognitive dysfunction versus complaints: a discrepancy in long-term findings. Neuropsychology Review 2002;12:114.CrossRefGoogle ScholarPubMed
Johnson, T, Monk, T, Rasmussen, LS, et al. Postoperative cognitive dysfunction in middle-aged patients. Anesthesiology 2002;96:13511357.CrossRefGoogle ScholarPubMed
Evered, LA, Silbert, B, Knopman, D, et al. Recommended nomenclature for perioperative cognitive disorders. British Journal of Anesthesiology 2018;121:10051012.Google Scholar
Price, CC, Garvan, CW, Monk, TG. Type and severity of cognitive decline in older adults after noncardiac surgery. Anesthesiology 2008;108:817.CrossRefGoogle ScholarPubMed
Price, CC, Tanner, JJ, Schmalfuss, I, et al. A pilot study evaluating presurgery neuroanatomical biomarkers for postoperative cognitive decline after total knee arthroplasty in older adults. Anesthesiology 2014;120:601613.Google Scholar
Monk, TG, Weldon, BC, Garvan, CW, et al. Predictors of cognitive dysfunction after major noncardiac surgery. Anesthesiology 2008;108:1830.Google Scholar
Abildstrom, H, Rasmussen, LS, Rentowl, P, et al. Cognitive dysfunction 1–2 years after non-cardiac surgery in the elderly. ISPOCD group. International Study of Post-Operative Cognitive Dysfunction. Acta Anaesthesiologica Scandinavica 2000;44:12461251.Google Scholar
Avidan, MS, Evers, AS. The fallacy of persistent postoperative cognitive decline. Anesthesiology 2016;124:255258.CrossRefGoogle ScholarPubMed
Eckenhoff, RG, Hogan, KJ, Evered, L. Fallacy … really? Anesthesiology 2016;125:426428.Google Scholar
Steinmetz, J, Christensen, KB, Lund, T, Lohse, N, Rasmussen, L, ISPOCD Group. Long-term consequences of postoperative cognitive dysfunction. Anesthesiology 2009;110:548555.Google Scholar
Schupf, N, Tang, MX, Albert, SM, et al. Decline in cognitive and functional skills increases mortality risk in nondemented elderly. Neurology 2005;65:12181226.Google Scholar
Vutskits, L, Xie, Z. Lasting impact of general anaesthesia on the brain: mechanisms and relevance. Nature Reviews Neuroscience 2016;17:705717.Google Scholar
O’Brien, H, Mohan, H, Hare, CO, Reynolds, JV, Kenny, RA. Mind over matter? The hidden epidemic of cognitive dysfunction in the older surgical patient. Annals of Surgery 2016;265:1.Google Scholar
Newman, MF, Croughwell, ND, Blumenthal, JA, et al. Predictors of cognitive decline after cardiac operation. Annals of Thoracic Surgery 1995;59:13261330.CrossRefGoogle ScholarPubMed
McDonagh, DL, Mathew, JP, White, WD, et al. Cognitive function after major noncardiac surgery, apolipoprotein E4 genotype, and biomarkers of brain injury. Anesthesiology 2010;112:852859.CrossRefGoogle ScholarPubMed
Martucci, KT, Mackey, SC. Imaging pain. Anesthesiology Clinics 2016;34:255269.CrossRefGoogle ScholarPubMed
Vaurio, LE, Sands, LP, Wang, Y, Mullen, EA, Leung, JM. Postoperative delirium: the importance of pain and pain management. Anesthesia & Analgesia 2006;102:12671273.CrossRefGoogle ScholarPubMed
Culley, DJ, Flaherty, D, Reddy, S, et al. Preoperative cognitive stratification of older elective surgical patients: a cross-sectional study. Anesthesia & Analgesia 2016;123:186192.Google Scholar
Culley, DJ, Flaherty, D, Fahey, MC, et al. Poor performance on a preoperative cognitive screening test predicts postoperative complications in older orthopedic surgical patients. Anesthesiology 2017;127:765774.Google Scholar
Leslie, M. The post-op brain. Science 2017;356:898900.Google Scholar
Sprung, J, Roberts, RO, Weingarten, TN, et al. Postoperative delirium in elderly patients is associated with subsequent cognitive impairment. British Journal of Anaesthesiology 2017;119:316323.CrossRefGoogle ScholarPubMed
Franck, M, Nerlich, K, Neuner, B, et al. No convincing association between post-operative delirium and post-operative cognitive dysfunction: a secondary analysis. Acta Anaesthesiologica Scandinavica 2016;60:14041414.Google Scholar
Culley, DJ, Crosby, G. Prehabilitation for prevention of postoperative cognitive dysfunction? Anesthesiology 2015;123:1.CrossRefGoogle ScholarPubMed
McDonald, SR, Heflin, MT, Whitson, HE, et al. Association of integrated care coordination with postsurgical outcomes in high-risk older adults: the Perioperative Optimization of Senior Health (POSH) initiative. JAMA Surgery 2018;153:454462.CrossRefGoogle ScholarPubMed
Cibelli, M, Fidalgo, AR, Terrando, N, et al. Role of interleukin-1beta in postoperative cognitive dysfunction. Annals of Neurology 2010;68:360368.Google Scholar
Fidalgo, AR, Cibelli, M, White, JPM, Nagy, I, Maze, M, Ma, D. Systemic inflammation enhances surgery-induced cognitive dysfunction in mice. Neuroscience Letters 2011;498:6366.CrossRefGoogle ScholarPubMed
Terrando, N, Monaco, C, Ma, D, Foxwell, BMJ, Feldmann, M, Maze, M. Tumor necrosis factor-α triggers a cytokine cascade yielding postoperative cognitive decline. Proceedings of the National Academy of Sciences of the United States of America 2010;107:2051820522.Google Scholar
Fidalgo, AR, Cibelli, M, White, JPM, et al. Peripheral orthopaedic surgery down-regulates hippocampal brain-derived neurotrophic factor and impairs remote memory in mouse. Neuroscience 2011;190:194199.Google Scholar
Canet, J, Raeder, J, Rasmussen, LS, et al. Cognitive dysfunction after minor surgery in the elderly. Acta Anaesthesiologica Scandinavica 2003;47:12041210.CrossRefGoogle ScholarPubMed
Evered, L, Scott, DA, Silbert, B, Maruff, P. Postoperative cognitive dysfunction is independent of type of surgery and anesthetic. Anesthesia & Analgesia 2011;112:11791185.CrossRefGoogle ScholarPubMed
Newman, MF, Kirchner, JL, Phillips-Bute, B, et al. Longitudinal assessment of neurocognitive function after coronary-artery bypass surgery. New England Journal of Medicine 2001;344:395402.Google Scholar
van Dijk, D, Spoor, M, Hijman, R, et al. Cognitive and cardiac outcomes 5 years after off-pump vs. on-pump coronary artery bypass graft surgery. JAMA 2007;297:701708.Google Scholar
Abdul-Jawad Altisent, O, Ferreira-Gonzalez, I, Marsal, JR, et al. Neurological damage after transcatheter aortic valve implantation compared with surgical aortic valve replacement in intermediate risk patients. Clinical Research in Cardiology 2016;105:508517.Google Scholar
Selnes, OA, Grega, MA, Borowicz, LM, Royall, RM, McKhann, GM, Baumgartner, WA. Cognitive changes with coronary artery disease: a prospective study of coronary artery bypass graft patients and nonsurgical controls. Annals of Thoracic Surgery 2003;75:137784.Google Scholar
Selnes, OA, Grega, MA, Bailey, MM, et al. Do management strategies for coronary artery disease influence 6-year cognitive outcomes? Annals of Thoracic Surgery 2009;88:445454.Google Scholar
Forsberg, A, Cervenka, S, Jonsson Fagerlund, M, et al. The immune response of the human brain to abdominal surgery. Annals of Neurology 2017;81:572582.Google Scholar
Choi, HA. The brain’s immune system hibernates in response to systemic injury. Science Translational Medicine 2017;9:eaan2771.Google Scholar
Culley, DJ, Baxter, M, Yukhananov, R, Crosby, G. The memory effects of general anesthesia persist for weeks in young and aged rats. Anesthesia & Analgesia 2003;96:10041009.Google Scholar
Xie, Z, Culley, DJ, Dong, Y, et al. The common inhalation anesthetic isoflurane induces caspase activation and increases amyloid-beta protein level in vivo. Annals of Neurology 2008;64:618627.Google Scholar
Planel, E, Bretteville, A, Liu, L, et al. Acceleration and persistence of neurofibrillary pathology in a mouse model of tauopathy following anesthesia. FASEB Journal 2009;23:25952604.Google Scholar
Futterer, CD, Maurer, MH, Schmitt, A, Feldmann, RE Jr., Kuschinsky, W, Waschke, KF. Alterations in rat brain proteins after desflurane anesthesia. Anesthesiology 2004;100:302308.CrossRefGoogle ScholarPubMed
Rasmussen, LS, Johnson, T, Kuipers, HM, et al. Does anaesthesia cause postoperative cognitive dysfunction? A randomised study of regional versus general anaesthesia in 438 elderly patients. Acta Anaesthesiologica Scandinavica 2003;47:260266.CrossRefGoogle ScholarPubMed
Sieber, FE, Gottshalk, A, Zakriya, KJ, Mears, SC, Lee, H. General anesthesia occurs frequently in elderly patients during propofol-based sedation and spinal anesthesia. Journal of Clinical Anesthesiology 2010;22:179183.Google Scholar
Purdon, PL, Pavone, KJ, Akeju, O, et al. The ageing brain: age-dependent changes in the electroencephalogram during propofol and sevoflurane general anaesthesia. British Journal of Anaesthesiology 2015;115:4657.Google Scholar
Silbert, BS, Evered, LA, Scott, DA. Incidence of postoperative cognitive dysfunction after general or spinal anaesthesia for extracorporeal shock wave lithotripsy. British Journal of Anaesthesiology 2014;113:784791.CrossRefGoogle ScholarPubMed
Chan, MT, Cheng, BC, Lee, TM, Gin, T, CODA Trial Group. BIS-guided anesthesia decreases postoperative delirium and cognitive decline. Journal of Neurosurgery & Anesthesiology 2013;25:3342.Google Scholar
Sprung, J, Roberts, RO, Knopman, DS, et al. Association of mild cognitive impairment with exposure to general anesthesia for surgical and nonsurgical procedures: a population-based study. Mayo Clinic Proceedings 2016;91:208217.Google Scholar
Sprung, J, Jankowski, CJ, Roberts, RO, et al. Anesthesia and incident dementia: a population-based, nested, case-control study. Mayo Clinic Proceedings 2013;88:552561.Google Scholar
Sprung, J, Roberts, RO, Knopman, DS, et al. Mild cognitive impairment and exposure to general anesthesia for surgeries and procedures: a population-based case-control study. Anesthesia & Analgesia 2017;124:12771290.Google Scholar
Hughes, CG, Patel, MB, Jackson, JC, et al. Surgery and anesthesia exposure is not a risk factor for cognitive impairment after major noncardiac surgery and critical illness. Annals of Surgery 2016;265:11261133.Google Scholar
Aiello Bowles, EJ, Larson, EB, Pong, RP, et al. Anesthesia exposure and risk of dementia and Alzheimer’s disease: a prospective study. Journal of the American Geriatrics Society 2016;64:602607.Google Scholar
Seitz, DP, Shah, PS, Herrmann, N, Beyene, J, Siddiqui, N. Exposure to general anesthesia and risk of Alzheimer’s disease: a systematic review and meta-analysis. BMC Geriatrics 2011;11:83.Google Scholar
Dokkedal, U, Hansen, TG, Rasmussen, LS, Mengel-From, J, Christensen, K. Cognitive functioning after surgery in middle-aged and elderly Danish twins. Anesthesiology 2016;124:312321.Google Scholar
Hogan, KJ, Bratzke, LC, Hogan, KL. Informed consent and cognitive dysfunction after noncardiac surgery in the elderly. Anesthesia & Analgesia 2018;126:629631.Google Scholar

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