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Chapter 14 - Heart Transplantation

Published online by Cambridge University Press:  19 August 2019

Michael T. Ashworth
Michael T. Ashworth
Affiliation:
Great Ormond Street Hospital for Children, London
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Summary

Following a brief introduction listing the salient aspects of heart transplantation as they pertain to children, there is a detailed section on assessment of the explanted heart with special reference to cardiomyopathy and congenital heart disease. This is followed by a section on the implanted heart that deals with the problems of acute cellular rejection, chronic allograft vasculopathy and post-transplant lymphoproliferative disorder. Particular attention is paid to endomyocardial biopsy in these assessments. The chapter closes with sections on re-explant and on post-mortem assessment of the transplanted heart.

Keywords

Explanted heartcardiomyopathymyocarditiscongenital heart diseaseacute cellular rejectionchronic allograft vasculopathyendomyocardial biopsyantibody-mediated rejectionpost-mortem
Type
Chapter
Information
Pathology of Heart Disease in the Fetus, Infant and Child
Autopsy, Surgical and Molecular Pathology
 , pp. 300 - 326
Publisher: Cambridge University Press
Print publication year: 2019

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References

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