Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-586b7cd67f-rdxmf Total loading time: 0 Render date: 2024-11-28T03:20:50.497Z Has data issue: false hasContentIssue false

Chapter 45 - Pregnancy after Liver Transplantation

from Section 7 - Hepato-Renal and Gastrointestinal Conditions in Pregnancy

Published online by Cambridge University Press:  23 February 2023

By
Neha Agrawal ,
Amira El-Messidi  and
Maged Peter Ghali
Edited by
Amira El-Messidi  and
Alan D. Cameron
Amira El-Messidi
Affiliation:
McGill University, Montréal
Alan D. Cameron
Affiliation:
University of Glasgow
Get access

Summary

A 29-year-old primigravida is a recipient of a liver transplant. She is referred by her primary care provider to your high-risk obstetrics clinic for consultation and prenatal care of a spontaneous intrauterine singleton pregnancy at 12+0 weeks’ gestation by dating sonogram. The patient takes prenatal vitamins and has no obstetric complaints.

Keywords

Liver transplantation, pregnancyComorbiditiesInvestigations, prenatalPerinatal risks, complications, maternal-fetal morbidity, adverse outcomeImmunosuppressive treatment, pharmacology, tacrolimus, prednisone, corticosteroidsAntenatal managementLiver enzymes, transaminases, differential diagnosisNonalcoholic steatohepatitisObstetric deliveryVaginal delivery, maternal corticosteroid stress dosesTransjugular intrahepatic portosystemic shunt (TIPS)Contraception
Type
Chapter
Information
OSCEs in Obstetrics and Maternal-Fetal Medicine
An Evidence-Based Approach
 , pp. 573 - 583
Publisher: Cambridge University Press
Print publication year: 2023

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Suggested Readings

Blume, C, Pischke, S, von Versen-Höynck, F, et al. Pregnancies in liver and kidney transplant recipients: a review of the current literature and recommendation. Best Pract Res Clin Obstet Gynaecol. 2014 Nov;28(8):1123–1136.Google Scholar
Jabiry-Zieniewicz, Z, Dabrowski, FA, Pietrzak, B, et al. Pregnancy in the liver transplant recipient. Liver Transpl. 2016 Oct;22(10):1408–1417.CrossRefGoogle ScholarPubMed
Marson, EJ, Kamarajah, SK, Dyson, JK, et al. Pregnancy outcomes in women with liver transplants: systematic review and meta-analysis. HPB (Oxford). 2020 Aug;22(8):1102–1111.Google Scholar
National Guideline Alliance (UK). Intrapartum Care for Women with Existing Medical Conditions or Obstetric Complications and Their Babies. London: National Institute for Health and Care Excellence (UK); 2019.Google Scholar
Parhar, KS, Gibson, PS, Coffin, CS. Pregnancy following liver transplantation: review of outcomes and recommendations for management. Can J Gastroenterol. 2012;26(9):621–626.Google Scholar
Rahim, MN, Long, L, Penna, L, et al. Pregnancy in liver transplantation. Liver Transpl. 2020 Apr;26(4):564–581.Google Scholar
Ramirez, CB, Doria, C. Pregnancy after liver transplantation. Best Pract Res Clin Obstet Gynaecol. 2014 Nov;28(8):1137–1145.Google Scholar
UK medical eligibility criteria for contraceptive use, 2016; amended Sept 2019. Available at www.fsrh.org. Accessed September 29, 2020.Google Scholar
Women in Hepatology Group; Italian Association for the Study of the Liver (AISF). AISF position paper on liver transplantation and pregnancy: Women in Hepatology Group, Italian Association for the Study of the Liver (AISF). Dig Liver Dis. 2016 Aug;48(8):860–868.Google Scholar
Zullo, F, Saccone, G, Donnarumma, L, et al. Pregnancy after liver transplantation: a case series and review of the literature. J Matern Fetal Neonatal Med. 2019 Oct;21:1–8.Google Scholar

Save book to Kindle

To save this book to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×