Skip to main content Accessibility help
×
Hostname: page-component-cd9895bd7-mkpzs Total loading time: 0 Render date: 2024-12-25T19:03:45.409Z Has data issue: false hasContentIssue false

Chapter 18 - Management of Neurogenic Lower Urinary Tract Dysfunction

Published online by Cambridge University Press:  13 October 2018

Krishnan Padmakumari Sivaraman Nair
Affiliation:
Royal Hallamshire Hospital, Sheffield
Marlís González-Fernández
Affiliation:
Johns Hopkins University Hospital, Baltimore, MD
Jalesh N. Panicker
Affiliation:
National Hospital for Neurology & Neurosurgery, London
Get access

Summary

Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Chapter
Information
Publisher: Cambridge University Press
Print publication year: 2018

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

de Groat, WC, Griffiths, D, Yoshimura, N Neural control of the lower urinary tract. Comprehensive Physiology 2015; 5(1): 327–96.Google Scholar
National Institute for Health and Care Excellence. Urinary incontinence in neurological disease: Management of lower urinary tract dysfunction in neurological disease. London, UK: National Institute for Health and Care Excellence: Guidance, 2012.Google Scholar
Esclarin de Ruz, A, Garcia Leoni, E, Herruzo Cabrera, R. Epidemiology and risk factors for urinary tract infection in patients with spinal cord injury. Journal of Urology 2000; 164(4): 1285–9.Google Scholar
Garcia Leoni, ME, Esclarin De Ruz, A. Management of urinary tract infection in patients with spinal cord injuries. Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2003; 9(8): 780–5.Google Scholar
Cardenas, DD, Hoffman, JM, Kirshblum, S, McKinley, W Etiology and incidence of rehospitalization after traumatic spinal cord injury: A multicenter analysis. Archives of Physical Medicine and Rehabilitation 2004; 85(11): 1757–63.Google Scholar
Murphy, DP, Lampert, V Current implications of drug resistance in spinal cord injury. American Journal of Physical Medicine & Rehabilitation. 2003; 82(1): 72–5.Google Scholar
Darouiche, RO, Al Mohajer, M, Siddiq, DM, Minard, CG Short versus long course of antibiotics for catheter-associated urinary tract infections in patients with spinal cord injury: A randomized controlled noninferiority trial. Archives of Physical Medicine and Rehabilitation 2014; 95(2): 290–6.Google Scholar
Poirier, C, Dinh, A, Salomon, J, Grall, N, Andremont, A, Bernard, L Prevention of urinary tract infections by antibiotic cycling in spinal cord injury patients and low emergence of multidrug resistant bacteria. Medecine et maladies infectieuses 2016; 46(6): 294–9.Google Scholar
Darouiche, RO, Green, BG, Donovan, WH, Chen, D, Schwartz, M, Merritt, J, et al. Multicenter randomized controlled trial of bacterial interference for prevention of urinary tract infection in patients with neurogenic bladder. Urology 2011; 78(2): 341–6.Google Scholar
Phé, V, Pakzad, M, Curtis, C, Porter, B, Haslam, C, Chataway, J, Panicker, JN. Urinary tract infections in multiple sclerosis. Mult. Scler. 2016; 22(7): 855–61. doi:10.1177/1352458516633903Google Scholar
Abrams, PH, Dunn, M, George, N Urodynamic findings in chronic retention of urine and their relevance to results of surgery. British Medical Journal 1978; 2(6147): 1258–60.Google Scholar
Drake, MJ, Apostolidis, A, Cocci, A, Emmanuel, A, Gajewski, JB, Harrison, SC, et al. Neurogenic lower urinary tract dysfunction: Clinical management recommendations of the Neurologic Incontinence committee of the fifth International Consultation on Incontinence 2013. Neurourology and Urodynamics 2016; 35(6): 657–65.Google Scholar
Deville, WL, Yzermans, JC, Van Duijn, NP, Bezemer, PD, Van der Windt, DA, Bouter, LM The urine dipstick test useful to rule out infections: A meta-analysis of the accuracy.BMC Urology 2004; 4: 4.Google Scholar
Nicolle, LE Urinary tract infections in patients with spinal injuries. Current Infectious Disease Reports 2014; 16(1): 390.Google Scholar
De Ridder, D, Vermeulen, C, Ketelaer, P, Van Poppel, H, Baert, L Pelvic floor rehabilitation in multiple sclerosis. Acta neurologica Belgica. 1999; 99(1): 61–4.Google Scholar
Weld, KJ, Dmochowski, RR Effect of bladder management on urological complications in spinal cord injured patients. Journal of Urology 2000; 163(3): 768–72.CrossRefGoogle ScholarPubMed
Killorin, W, Gray, M, Bennett, JK, Green, BG The value of urodynamics and bladder management in predicting upper urinary tract complications in male spinal cord injury patients. Paraplegia 1992; 30(6): 437–41.Google Scholar
Averbeck, MA, Altaweel, W, Manu-Marin, A, Madersbacher, H Management of LUTS in patients with dementia and associated disorders. Neurourology and Urodynamics 2017; 36(2): 245–52.Google Scholar
Abrams, P, Agarwal, M, Drake, M, El-Masri, W, Fulford, S, Reid, S, et al. A proposed guideline for the urological management of patients with spinal cord injury. BJU Int. 2008;101(8):989–94.Google Scholar
Lapides, J, Diokno, AC, Silber, SJ, Lowe, BS Clean, intermittent self-catheterization in the treatment of urinary tract disease. Journal of Urology 1972; 107(3): 458–61.CrossRefGoogle ScholarPubMed
Moore, KN, Fader, M, Getliffe, K Long-term bladder management by intermittent catheterisation in adults and children. Cochrane Database of Systematic Reviews 2007; 4: CD006008.Google Scholar
Herschorn, S, Gajewski, J, Ethans, K, Corcos, J, Carlson, K, Bailly, G, et al. Efficacy of botulinum toxin A injection for neurogenic detrusor overactivity and urinary incontinence: A randomized, double-blind trial. Journal of Urology 2011; 185(6): 2229–35.Google Scholar
Lindehall, B, Abrahamsson, K, Jodal, U, Olsson, I, Sillen, U Complications of clean intermittent catheterization in young females with myelomeningocele: 10 to 19 years of followup. Journal of Urology 2007; 178(3 Pt. 1): 1053–5.Google Scholar
Game, X, Castel-Lacanal, E, Bentaleb, Y, Thiry-Escudie, I, De Boissezon, X, Malavaud, B, et al. Botulinum toxin A detrusor injections in patients with neurogenic detrusor overactivity significantly decrease the incidence of symptomatic urinary tract infections. European Urology 2008; 53(3): 613–18.CrossRefGoogle ScholarPubMed
Feifer, A, Corcos, J Contemporary role of suprapubic cystostomy in treatment of neuropathic bladder dysfunction in spinal cord injured patients. Neurourology and Urodynamics 2008; 27(6): 475–9.Google Scholar
National Institute for Health and Care Excellence. Urinary incontinence in neurological disease (CG148). London, UK: National Institute for Health and Care Excellence, 2012.Google Scholar
Broecker, BH, Klein, FA, Hackler, RH Cancer of the bladder in spinal cord injury patients. Journal of Urology 1981; 125(2): 196–7.CrossRefGoogle ScholarPubMed
Navon, JD, Soliman, H, Khonsari, F, Ahlering, T Screening cystoscopy and survival of spinal cord injured patients with squamous cell cancer of the bladder. Journal of Urology 1997; 157(6): 2109–11.Google Scholar
Hamid, R, Bycroft, J, Arya, M, Shah, PJ Screening cystoscopy and biopsy in patients with neuropathic bladder and chronic suprapubic indwelling catheters: Is it valid? Journal of Urology 2003; 170(2 Pt. 1): 425–7.Google Scholar
Denys, MA, Viaene, A, Goessaert, AS, Van Haverbeke, F, Hoebeke, P, Raes, A, et al. Circadian rhythms in water and solute handling in adults with a spinal cord injury. Journal of Urology 2017; 197(2): 445–51.Google Scholar
Abrams, P, Amarenco, G, Bakke, A, Buczynski, A, Castro-Diaz, D, Harrison, S, et al. Tamsulosin: Efficacy and safety in patients with neurogenic lower urinary tract dysfunction due to suprasacral spinal cord injury. Journal of Urology 2003; 170(4 Pt. 1): 1242–51.Google Scholar
Gallien, P, Reymann, JM, Amarenco, G, Nicolas, B, de Seze, M, Bellissant, E Placebo controlled, randomised, double blind study of the effects of botulinum A toxin on detrusor sphincter dyssynergia in multiple sclerosis patients. Journal of Neurology, Neurosurgery, and Psychiatry 2005; 76(12): 1670–6.Google Scholar
Madhuvrata, P, Singh, M, Hasafa, Z, Abdel-Fattah, M Anticholinergic drugs for adult neurogenic detrusor overactivity: A systematic review and meta-analysis. European Urology 2012; 62(5): 816–30.Google Scholar
Gajewski, JB, Awad, SA Oxybutynin versus propantheline in patients with multiple sclerosis and detrusor hyperreflexia. Journal of Urology 1986; 135(5): 966–8.Google Scholar
Stohrer, M, Murtz, G, Kramer, G, Schnabel, F, Arnold, EP, Wyndaele, JJ, et al. Propiverine compared to oxybutynin in neurogenic detrusor overactivity: Results of a randomized, double-blind, multicenter clinical study. European Urology 2007; 51(1): 235–42.Google Scholar
Franco, I, Horowitz, M, Grady, R, Adams, RC, de Jong, TP, Lindert, K, et al. Efficacy and safety of oxybutynin in children with detrusor hyperreflexia secondary to neurogenic bladder dysfunction. Journal of Urology 2005; 173(1): 221–5.Google Scholar
Stohrer, M, Madersbacher, H, Richter, R, Wehnert, J, Dreikorn, K Efficacy and safety of propiverine in SCI-patients suffering from detrusor hyperreflexia: A double-blind, placebo-controlled clinical trial. Spinal Cord 1999; 37(3): 196200.Google Scholar
Stohrer, M, Bauer, P, Giannetti, BM, Richter, R, Burgdorfer, H, Murtz, G Effect of trospium chloride on urodynamic parameters in patients with detrusor hyperreflexia due to spinal cord injuries: A multicentre placebo-controlled double-blind trial. Urologia internationalis 1991; 47(3): 138–43.Google Scholar
Ethans, KD, Nance, PW, Bard, RJ, Casey, AR, Schryvers, OI Efficacy and safety of tolterodine in people with neurogenic detrusor overactivity. Journal of Spinal Cord Medicine 2004; 27(3): 214–18.Google Scholar
Reddy, PP, Borgstein, NG, Nijman, RJ, Ellsworth, PI Long-term efficacy and safety of tolterodine in children with neurogenic detrusor overactivity. Journal of Pediatric Urology 2008; 4(6): 428–33.CrossRefGoogle ScholarPubMed
Amarenco, G, Sutory, M, Zachoval, R, Agarwal, M, Del Popolo, G, Tretter, R, et al. Solifenacin is effective and well tolerated in patients with neurogenic detrusor overactivity: Results from the double-blind, randomized, active- and placebo-controlled SONIC urodynamic study. Neurourology and Urodynamics 2017; 36(2): 414–21.Google Scholar
Amend, B, Hennenlotter, J, Schafer, T, Horstmann, M, Stenzl, A, Sievert, KD Effective treatment of neurogenic detrusor dysfunction by combined high-dosed antimuscarinics without increased side-effects. European Urology 2008; 53(5): 1021–8.Google Scholar
Wollner, J, Pannek, J Initial experience with the treatment of neurogenic detrusor overactivity with a new beta-3 agonist (mirabegron) in patients with spinal cord injury. Spinal Cord 2016; 54(1): 7882.Google Scholar
Schurch, B, Stohrer, M, Kramer, G, Schmid, DM, Gaul, G, Hauri, D Botulinum-A toxin for treating detrusor hyperreflexia in spinal cord injured patients: A new alternative to anticholinergic drugs? Preliminary results. Journal of Urology. 2000; 164(3 Pt. 1): 692–7.Google Scholar
Schurch, B, de Seze, M, Denys, P, Chartier-Kastler, E, Haab, F, Everaert, K, et al. Botulinum toxin type a is a safe and effective treatment for neurogenic urinary incontinence: Results of a single treatment, randomized, placebo controlled 6-month study. Journal of Urology 2005; 174(1): 196200.Google Scholar
Cruz, F, Herschorn, S, Aliotta, P, Brin, M, Thompson, C, Lam, W, et al. Efficacy and safety of onabotulinumtoxinA in patients with urinary incontinence due to neurogenic detrusor overactivity: A randomised, double-blind, placebo-controlled trial. European Urology 2011; 60(4): 742–50.Google Scholar
Denys, P, Del Popolo, G, Amarenco, G, Karsenty, G, Le Berre, P, Padrazzi, B, et al. Efficacy and safety of two administration modes of an intra-detrusor injection of 750 units dysport(R) (abobotulinumtoxinA) in patients suffering from refractory neurogenic detrusor overactivity (NDO): A randomised placebo-controlled phase IIa study. Neurourology and Urodynamics 2017; 36(2): 457–62.Google Scholar
Giannantoni, A, Conte, A, Proietti, S, Giovannozzi, S, Rossi, A, Fabbrini, G, et al. Botulinum toxin type A in patients with Parkinson’s disease and refractory overactive bladder. Journal of Urology 2011; 186(3): 960–4.Google Scholar
de Seze, M, Raibaut, P, Gallien, P, Even-Schneider, A, Denys, P, Bonniaud, V, et al. Transcutaneous posterior tibial nerve stimulation for treatment of the overactive bladder syndrome in multiple sclerosis: Results of a multicenter prospective study. Neurourology and Urodynamics 2011; 30(3): 306–11.Google Scholar
Wallace, PA, Lane, FL, Noblett, KL Sacral nerve neuromodulation in patients with underlying neurologic disease. Am. J. Obstet. Gynecol. 2007; 197(1): 96 e1-5.Google Scholar
Engeler, DS, Meyer, D, Abt, D, Muller, S, Schmid, HP Sacral neuromodulation for the treatment of neurogenic lower urinary tract dysfunction caused by multiple sclerosis: A single-centre prospective series. BMC Urology 2015; 15: 105.Google Scholar
Mundy, AR, Stephenson, TP ‘Clam’ ileocystoplasty for the treatment of refractory urge incontinence. British Journal of Urology 1985; 57(6): 641–6.Google Scholar
Khastgir, J, Hamid, R, Arya, M, Shah, N, Shah, PJ Surgical and patient reported outcomes of ‘clam’ augmentation ileocystoplasty in spinal cord injured patients. European Urology 2003; 43(3): 263–9.Google Scholar
Perrouin-Verbe, MA, Chartier-Kastler, E, Even, A, Denys, P, Roupret, M, Phe, V Long-term complications of continent cutaneous urinary diversion in adult spinal cord injured patients. Neurourology and Urodynamics 2016; 35(8): 1046–50.Google Scholar
Atala, A Tissue engineering of artificial organs. J. Endourol. 2000; 14(1): 4957.Google Scholar
Legrand, G, Roupret, M, Comperat, E, Even-Schneider, A, Denys, P, Chartier-Kastler, E Functional outcomes after management of end-stage neurological bladder dysfunction with ileal conduit in a multiple sclerosis population: A monocentric experience. Urology 2011; 78(4): 937–41.Google Scholar
Chancellor, MB, Erhard, MJ, Rivas, DA Clinical effect of alpha-1 antagonism by terazosin on external and internal urinary sphincter function. J. Am. Paraplegia Soc. 1993; 16(4): 207–14.Google Scholar
Hussain, M, Greenwell, TJ, Shah, J, Mundy, A Long-term results of a self-expanding wallstent in the treatment of urethral stricture. BJU Int. 2004; 94(7): 1037–9.Google Scholar
Reynard, JM, Vass, J, Sullivan, ME, Mamas, M Sphincterotomy and the treatment of detrusor-sphincter dyssynergia: Current status, future prospects. Spinal Cord 2003; 41(1): 111.Google Scholar
Pan, D, Troy, A, Rogerson, J, Bolton, D, Brown, D, Lawrentschuk, N Long-term outcomes of external sphincterotomy in a spinal injured population. Journal Urology 2009; 181(2): 705–9.Google Scholar
Hussain, M, Greenwell, TJ, Venn, SN, Mundy, AR The current role of the artificial urinary sphincter for the treatment of urinary incontinence. Journal Urology 2005; 174(2): 418–24.Google Scholar
Phe, V, Leon, P, Granger, B, Denys, P, Bitker, MO, Mozer, P, et al. Stress urinary incontinence in female neurological patients: Long-term functional outcomes after artificial urinary sphincter (AMS 800TM) implantation. Neurourology and Urodynamics 2017; 36(3): 764–9.Google Scholar
Lai, HH, Hsu, EI, Teh, BS, Butler, EB, Boone, TB 13 years of experience with artificial urinary sphincter implantation at Baylor College of Medicine. Journal of Urology 2007; 177(3): 1021–5.Google Scholar
Gilling, PJ, Bell, DF, Wilson, LC, Westenberg, AM, Reuther, R, Fraundorfer, MR An adjustable continence therapy device for treating incontinence after prostatectomy: A minimum 2-year follow-up. BJU Int. 2008; 102(10): 1426–30; discussion 30–1.Google Scholar
Bauer, RM, Grabbert, MT, Klehr, B, Gebhartl, P, Gozzi, C, Homberg, R, et al. 36-month data for the AdVance XP(R) male sling: Results of a prospective multicentre study. BJU Int. 2017; 119(4): 626–30.CrossRefGoogle Scholar
Farag, F, Koens, M, Sievert, KD, De Ridder, D, Feitz, W, Heesakkers, J Surgical treatment of neurogenic stress urinary incontinence: A systematic review of quality assessment and surgical outcomes. Neurourology and Urodynamics 2016; 35(1): 21–5.Google Scholar
Ren, J, Chew, DJ, Biers, S, Thiruchelvam, N Electrical nerve stimulation to promote micturition in spinal cord injury patients: A review of current attempts. Neurourology and Urodynamics 2016; 35(3): 365–70.Google Scholar

Save book to Kindle

To save this book to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×