Book contents
- Neuromuscular Disease: A Case-Based Approach
- Neuromuscular Disease
- Copyright page
- Contents
- Contributors
- Foreword
- Preface to 2nd Edition
- Part I Evaluation and Treatment of Patients with a Neuromuscular Disorder
- Part II Neuromuscular Cases
- Disorders of the Anterior Horn Cell
- Peripheral Neuropathies
- Case 9 Guillain–Barré Syndrome (GBS) and Miller–Fisher Syndrome (MFS)
- Case 10 Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
- Case 11 IgM Anti-MAG Polyneuropathy
- Case 12 Polyneuropathy, Organomegaly, Endocrine Manifestations, Monoclonal Protein, and Skin Changes (POEMS) Syndrome
- Case 13 Vasculitic Neuropathy
- Case 14 Small-Fibre Neuropathy (SFN)
- Case 15 Sensory Neuronopathy (SNN, Ganglionopathy)
- Case 16 Wartenberg Migrant Sensory Neuropathy
- Case 17 Multifocal Motor Neuropathy (MMN)
- Case 18 Peripheral Nerve Hyperexcitability Syndromes: Morvan Syndrome
- Case 19 Idiopathic Brachial Plexus Neuropathy, Neuralgic Amyotrophy (NA)
- Case 20 Diabetic Neuropathy
- Case 21 Alcoholic Polyneuropathy
- Case 22 Chronic Idiopathic Axonal Polyneuropathy (CIAP)
- Case 23 Critical Illness Polyneuropathy and Myopathy (CIPM)
- Case 24 Drug-Induced Polyneuropathies: Amiodarone Polyneuropathy
- Case 25 Lyme Radiculopathy
- Case 26 Leprosy
- Case 27 Charcot–Marie–Tooth Disease (CMT) Type 1A/Hereditary Neuropathy with Liability for Pressure Palsies (HNPP)
- Case 28 Charcot–Marie–Tooth Disease (CMT) Type 2 A and Type 2B
- Case 29 Hereditary Sensory and Autonomic Neuropathy (HSAN) Type 4
- Case 30 Hereditary Transthyretin (TTR) Amyloidosis
- Disorders of the Neuromuscular Junction
- Myopathies
- Video legends
- Index
- References
Case 14 - Small-Fibre Neuropathy (SFN)
from Peripheral Neuropathies
Published online by Cambridge University Press: 29 November 2024
Book contents
- Neuromuscular Disease: A Case-Based Approach
- Neuromuscular Disease
- Copyright page
- Contents
- Contributors
- Foreword
- Preface to 2nd Edition
- Part I Evaluation and Treatment of Patients with a Neuromuscular Disorder
- Part II Neuromuscular Cases
- Disorders of the Anterior Horn Cell
- Peripheral Neuropathies
- Case 9 Guillain–Barré Syndrome (GBS) and Miller–Fisher Syndrome (MFS)
- Case 10 Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
- Case 11 IgM Anti-MAG Polyneuropathy
- Case 12 Polyneuropathy, Organomegaly, Endocrine Manifestations, Monoclonal Protein, and Skin Changes (POEMS) Syndrome
- Case 13 Vasculitic Neuropathy
- Case 14 Small-Fibre Neuropathy (SFN)
- Case 15 Sensory Neuronopathy (SNN, Ganglionopathy)
- Case 16 Wartenberg Migrant Sensory Neuropathy
- Case 17 Multifocal Motor Neuropathy (MMN)
- Case 18 Peripheral Nerve Hyperexcitability Syndromes: Morvan Syndrome
- Case 19 Idiopathic Brachial Plexus Neuropathy, Neuralgic Amyotrophy (NA)
- Case 20 Diabetic Neuropathy
- Case 21 Alcoholic Polyneuropathy
- Case 22 Chronic Idiopathic Axonal Polyneuropathy (CIAP)
- Case 23 Critical Illness Polyneuropathy and Myopathy (CIPM)
- Case 24 Drug-Induced Polyneuropathies: Amiodarone Polyneuropathy
- Case 25 Lyme Radiculopathy
- Case 26 Leprosy
- Case 27 Charcot–Marie–Tooth Disease (CMT) Type 1A/Hereditary Neuropathy with Liability for Pressure Palsies (HNPP)
- Case 28 Charcot–Marie–Tooth Disease (CMT) Type 2 A and Type 2B
- Case 29 Hereditary Sensory and Autonomic Neuropathy (HSAN) Type 4
- Case 30 Hereditary Transthyretin (TTR) Amyloidosis
- Disorders of the Neuromuscular Junction
- Myopathies
- Video legends
- Index
- References
Summary
A 48-year-old man had complained about the painful soles of his feet for several months. This pain was present constantly but increased on touch and when walking. He was a marathon runner but could no longer train or walk properly because of the pain. He did not report weakness, sensory disturbances, discoloration of his feet, or swelling of his joints. Otherwise, he was healthy. He was not known to have diabetes mellitus or any other chronic disorder, such as sarcoidosis, which can cause a painful neuropathy. There were no cardiovascular or intestinal complaints, and no symptoms of autonomic dysfunction. Symptoms that could suggest malignancy were absent. He did not use any medication, had not been treated with any neurotoxic drug earlier, did not smoke, and drank only very limited amounts of alcohol. There was no family history of neurological disorders.
- Type
- Chapter
- Information
- Neuromuscular DiseaseA Case-Based Approach, pp. 110 - 113Publisher: Cambridge University PressPrint publication year: 2024
References
Suggested Reading
Chan, ACY, Kumar, S, Tan, G, et al. Expanding the genetic causes of small-fiber neuropathy: SCN genes and beyond. Muscle Nerve 2023;67(4):259–271. doi: 10.1002/mus.27752. Epub 2022 Nov 30. PMID: 36448457.CrossRefGoogle ScholarPubMed
Devigili, G, Cazzato, D, Lauria, G. Clinical diagnosis and management of small fiber neuropathy: an update on best practice. Expert Rev Neurother 2020;20(9):967–980. doi: 10.1080/14737175.2020.1794825. Epub 2020 Jul 23. PMID: 32654574.CrossRefGoogle ScholarPubMed
Geerts, M, de Greef, BTA, Sopacua, M, et al. Intravenous immunoglobulin therapy in patients with painful idiopathic small fiber neuropathy. Neurology 2021;96(20):e2534–e2545. doi: 10.1212/WNL.0000000000011919. Epub 2021 Mar 25. PMID: 33766992; PMCID: PMC8205474.CrossRefGoogle ScholarPubMed
Hoeijmakers, JGJ, Merkies, ISJ, Faber, CG. Small fiber neuropathies: expanding their etiologies. Curr Opin Neurol 2022;35(5):545–552. doi: 10.1097/WCO.0000000000001103. Epub 2022 Aug 11. PMID: 35950732.Google ScholarPubMed
Sopacua, M, Hoeijmakers, JGJ, Merkies, ISJ, et al. Small-fiber neuropathy: expanding the clinical pain universe. J Peripher Nerv Syst 2019;24(1):19–33. doi: 10.1111/jns.12298. Epub 2019 Jan 8. PMID: 30569495.CrossRefGoogle ScholarPubMed
Terkelsen, AJ, Karlsson, P, Lauria, G, et al. The diagnostic challenge of small fibre neuropathy: clinical presentations, evaluations, and causes. Lancet Neurol 2017;16(11):934–944. doi: 10.1016/S1474-4422(17)30329-0. Erratum in: Lancet Neurol. 2017 Dec;16(12):954. PMID: 29029847.CrossRefGoogle ScholarPubMed