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Published online by Cambridge University Press:  21 November 2024

James Dolbow
Affiliation:
University Hospitals Cleveland Medical Center
Neel Fotedar
Affiliation:
University Hospitals Cleveland Medical Center
Joshua Edmondson
Affiliation:
University Hospital Cleveland Medical Centter
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Summary

Named after George Gilles de la Tourette who published an in-depth description of the disorder in 1885, Tourette syndrome (TS) is a pediatric tic disorder with a 3:1 male predominance. Though there is ample evidence that tic disorders are often familial, research has not found a definitive gene associated with the inheritance of TS. Many theories exist about the pathogenesis of TS, most of which center around the hypothesis that there is some sort of dopamine abnormality in the striatum, a pathogenesis that is supported by the fact that tics more commonly occur in patients with dopamine irregularity such as patients with Parkinson disease or Huntington disease.

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The Neurology Riddle Book
150 Common and Rare Neurological Diseases in Riddle Form
, pp. 273 - 276
Publisher: Cambridge University Press
Print publication year: 2024

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  • 87
  • James Dolbow, University Hospitals Cleveland Medical Center, Neel Fotedar, University Hospitals Cleveland Medical Center, Joshua Edmondson, University Hospital Cleveland Medical Centter
  • Book: The Neurology Riddle Book
  • Online publication: 21 November 2024
  • Chapter DOI: https://doi.org/10.1017/9781009527378.089
Available formats
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Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

  • 87
  • James Dolbow, University Hospitals Cleveland Medical Center, Neel Fotedar, University Hospitals Cleveland Medical Center, Joshua Edmondson, University Hospital Cleveland Medical Centter
  • Book: The Neurology Riddle Book
  • Online publication: 21 November 2024
  • Chapter DOI: https://doi.org/10.1017/9781009527378.089
Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • 87
  • James Dolbow, University Hospitals Cleveland Medical Center, Neel Fotedar, University Hospitals Cleveland Medical Center, Joshua Edmondson, University Hospital Cleveland Medical Centter
  • Book: The Neurology Riddle Book
  • Online publication: 21 November 2024
  • Chapter DOI: https://doi.org/10.1017/9781009527378.089
Available formats
×