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39 - Nutrition in the neonatal surgical patient

Published online by Cambridge University Press:  10 December 2009

Patti J. Thureen
By
Agostino Pierro  and
Simon Eaton
Edited by
William W. Hay
Patti J. Thureen
Affiliation:
University of Colorado at Denver and Health Sciences Center
Agostino Pierro
Affiliation:
Department of Paediatric Surgery, The Institute of Child Health and Great Ormond Street Hospital for Children NHS Trust, University College London, London, UK
Simon Eaton
Affiliation:
Department of Paediatric Surgery, The Institute of Child Health and Great Ormond Street Hospital for Children NHS Trust, University College London, London, UK
William W. Hay
Affiliation:
University of Colorado at Denver and Health Sciences Center
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Summary

Introduction

The newborn infant is in a “critical epoch” of development not only for the organism as a whole but also for the individual organs and most significantly for the brain. Adequate nutrition in the neonatal period is necessary to avoid the adverse effects of malnutrition on morbidity and mortality and to minimise the future menace of stunted mental and physical development.

The survival rate of newborn infants affected by isolated congenital gastrointestinal abnormalities has improved considerably over the past 20 years and is now in excess of 90% in most pediatric surgical centers. The introduction of parenteral nutrition and advancement in nutritional management are certainly among the main factors responsible for this improvement.

Historical background

Parenteral nutrition stepped forward from numerous historical anecdotes in the 1930s with the first successful infusion of protein hydrolysates in humans, followed by the first report of successful total parenteral nutrition in an infant in 1944, and given a huge boost by the first placement of a catheter in the superior vena cava to deliver nutrients for prolonged periods. Using this system, Dudrick and Wilmore showed that adequate growth and development could be achieved in beagle puppies and in a surgical infant. Following these initial reports Filler and co-authors reported the first series of surgical neonates with gastrointestinal abnormalities treated with long-term total parenteral nutrition.

Type
Chapter
Information
Neonatal Nutrition and Metabolism , pp. 569 - 585
Publisher: Cambridge University Press
Print publication year: 2006

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  • Nutrition in the neonatal surgical patient
    • By Agostino Pierro, Department of Paediatric Surgery, The Institute of Child Health and Great Ormond Street Hospital for Children NHS Trust, University College London, London, UK, Simon Eaton, Department of Paediatric Surgery, The Institute of Child Health and Great Ormond Street Hospital for Children NHS Trust, University College London, London, UK
  • Patti J. Thureen, University of Colorado at Denver and Health Sciences Center
  • Edited by William W. Hay, University of Colorado at Denver and Health Sciences Center
  • Book: Neonatal Nutrition and Metabolism
  • Online publication: 10 December 2009
  • Chapter DOI: https://doi.org/10.1017/CBO9780511544712.040
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  • Nutrition in the neonatal surgical patient
    • By Agostino Pierro, Department of Paediatric Surgery, The Institute of Child Health and Great Ormond Street Hospital for Children NHS Trust, University College London, London, UK, Simon Eaton, Department of Paediatric Surgery, The Institute of Child Health and Great Ormond Street Hospital for Children NHS Trust, University College London, London, UK
  • Patti J. Thureen, University of Colorado at Denver and Health Sciences Center
  • Edited by William W. Hay, University of Colorado at Denver and Health Sciences Center
  • Book: Neonatal Nutrition and Metabolism
  • Online publication: 10 December 2009
  • Chapter DOI: https://doi.org/10.1017/CBO9780511544712.040
Available formats
×

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To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • Nutrition in the neonatal surgical patient
    • By Agostino Pierro, Department of Paediatric Surgery, The Institute of Child Health and Great Ormond Street Hospital for Children NHS Trust, University College London, London, UK, Simon Eaton, Department of Paediatric Surgery, The Institute of Child Health and Great Ormond Street Hospital for Children NHS Trust, University College London, London, UK
  • Patti J. Thureen, University of Colorado at Denver and Health Sciences Center
  • Edited by William W. Hay, University of Colorado at Denver and Health Sciences Center
  • Book: Neonatal Nutrition and Metabolism
  • Online publication: 10 December 2009
  • Chapter DOI: https://doi.org/10.1017/CBO9780511544712.040
Available formats
×