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Chapter 10 - Obesity and Mental Health

Published online by Cambridge University Press:  14 October 2021

By
Aoife M. Egan
Edited by
Anne M. Doherty ,
Aoife M. Egan  and
Sean Dinneen
Anne M. Doherty
Affiliation:
University College Dublin
Aoife M. Egan
Affiliation:
Division of Endocrinology and Metabolism, Mayo Clinic, Minnesota, USA
Sean Dinneen
Affiliation:
School of Medicine, National University of Ireland, Galway
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Summary

Over 650 million people live with obesity worldwide, and almost all countries are affected by what is considered a global obesity pandemic. It is one of the factors that contribute to excess premature mortality in patients with severe mental illness, who die 15–20 years younger than the general population. Both obesity and mental health disorders are highly prevalent and frequently occur in the same individual. While weight loss is typically associated with improvements in psychological functioning, a certain proportion of patients will develop new psychological issues or experience a relapse of pre-existing conditions. Further work is needed to clarify the underlying biological mechanisms explaining the relationship between obesity and mental health. In the interim, people with obesity should receive care in a multidisciplinary setting with access to mental healthcare integrated with their obesity care.

Keywords

endocrinologyobesitydiabetesdepressionmental health
Type
Chapter
Information
Mental Health, Diabetes and Endocrinology , pp. 106 - 115
Publisher: Cambridge University Press
Print publication year: 2021

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References

World Health Organization. Obesity. Available from: www.who.int/topics/obesity/enGoogle Scholar
Afshin, A, Forouzanfar, MH, Reitsma, MB, Sur, P, Estep, K, Lee, A, et al. Health effects of overweight and obesity in 195 countries over 25 years. N Engl J Med. 2017; 377(1): 13–27.Google ScholarPubMed
Wahlbeck, K, Westman, J, Nordentoft, M, Gissler, M, Laursen, TM. Outcomes of Nordic mental health systems: life expectancy of patients with mental disorders. Br J Psychiatry. 2011; 199(6): 453–8.CrossRefGoogle ScholarPubMed
Barber, S, Thornicroft, G. Reducing the mortality gap in people with severe mental disorders: the role of lifestyle psychosocial interventions. Front Psychiatry. 2018; 9: 463.CrossRefGoogle ScholarPubMed
World Health Organization. The World Health Report 2001: Mental disorders affect one in four people, 2001. Available from: www.who.int/whr/2001/media_centre/press_release/enGoogle Scholar
Luppino, FS, de Wit, LM, Bouvy, PF, Stijnen, T, Cuijpers, P, Penninx, BWJH, Zitman, FG. Overweight, obesity, and depression: a systematic review and meta-analysis of longitudinal studies. Arch Gen Psychiatry. 2010; 67(3): 220–9.Google Scholar
Franko, DL, Striegel-Moore, RH, Thompson, D, Schreiber, GB, Daniels, SR. Does adolescent depression predict obesity in black and white young adult women? Psychol Med. 2005; 35(10): 1505–13.Google Scholar
Fiedorowicz, JG, Palagummi, NM, Forman-Hoffman, VL, Miller, DD, Haynes, WG. Elevated prevalence of obesity, metabolic syndrome, and cardiovascular risk factors in bipolar disorder. Ann Clin Psychiatry. 2008; 20(3): 131–7.CrossRefGoogle ScholarPubMed
Avila, C, Holloway, AC, Hahn, MK, Morrison, KM, Restivo, M, Anglin, R, Taylor, VH. An overview of links between obesity and mental health. Curr Obes Rep. 2015; 4(3): 303–10.Google Scholar
Taylor, VH, McIntyre, RS, Remington, G, Levitan, RD, Stonehocker, B, Sharma, AM. Beyond pharmacotherapy: understanding the links between obesity and chronic mental illness. Can J Psychiatry. 2012; 57(1): 5–12.Google Scholar
Brown, ES, Varghese, FP, McEwen, BS. Association of depression with medical illness: does cortisol play a role? Biol Psychiatry. 2004; 55(1): 1–9.Google Scholar
Shelton, RC, Miller, AH. Inflammation in depression: is adiposity a cause? Dialogues Clin Neurosci. 2011; 13(1): 41–53.Google Scholar
Kemp, DE. Managing the side effects associated with commonly used treatments for bipolar depression. J Affect Disord. 2014; 169(Suppl. 1): S34–44.CrossRefGoogle ScholarPubMed
Sarwer, DB, Polonsky, HM. The psychosocial burden of obesity. Endocrinol Metab Clin North Am. 2016; 45(3): 677–88.Google Scholar
Onyike, CU, Crum, RM, Lee, HB, Lyketsos, CG, Eaton, WW. Is obesity associated with major depression? Results from the Third National Health and Nutrition Examination Survey. Am J Epidemiol. 2003; 158(12): 1139–47.Google Scholar
Tronieri, JS, Wurst, CM, Pearl, RL, Allison, KC. Sex differences in obesity and mental health. Curr Psychiatry Rep. 2017; 19(6): 29.CrossRefGoogle ScholarPubMed
Mueser, KT, McGurk, SR. Schizophrenia. Lancet. 2004; 363(9426): 2063–72.Google Scholar
Britvic, D, Maric, NP, Doknic, M, Pekic, S, Andric, S, Jasovic-Gasic, M, Popovic, V. Metabolic issues in psychotic disorders with the focus on first-episode patients: a review. Psychiatr Danub. 2013; 25(4): 410–5.Google Scholar
Zipursky, RB, Gu, H, Green, AI, Perkins, DO, Tohen, MF, McEvoy, JP, et al. Course and predictors of weight gain in people with first-episode psychosis treated with olanzapine or haloperidol. Br J Psychiatry. 2005; 187: 537–43.Google Scholar
Amani, R. Is dietary pattern of schizophrenia patients different from healthy subjects? BMC Psychiatry. 2007; 7: 15.Google Scholar
Koskinen, J, Löhönen, J, Koponen, H, Isohanni, M, Miettunen, J. Rate of cannabis use disorders in clinical samples of patients with schizophrenia: a meta-analysis. Schizophr Bull. 2010; 36(6): 1115–30.CrossRefGoogle ScholarPubMed
Nurjono, M, Neelamekam, S, Lee, J. Serum leptin and its relationship with psychopathology in schizophrenia. Psychoneuroendocrinology. 2014; 50: 149–54.Google Scholar
Sentissi, O, Epelbaum, J, Olié, J-P, Poirier, M-F. Leptin and ghrelin levels in patients with schizophrenia during different antipsychotics treatment: a review. Schizophr Bull. 2008; 34(6): 1189–99.CrossRefGoogle ScholarPubMed
Al-Harithy, RN. Relationship of leptin concentration to gender, body mass index and age in Saudi adults. Saudi Med J. 2004; 25(8): 1086–90.Google ScholarPubMed
Polanczyk, G, de Lima, MS, Horta, BL, Biederman, J, Rohde, LA. The worldwide prevalence of ADHD: a systematic review and metaregression analysis. Am J Psychiatry. 2007; 164(6): 942–8.CrossRefGoogle ScholarPubMed
Faraone, SV, Biederman, J, Mick, E. The age-dependent decline of attention deficit hyperactivity disorder: a meta-analysis of follow-up studies. Psychol Med. 2006; 36(2): 159–65.Google Scholar
Moreira-Maia, CR, Massuti, R, Tessari, L, Campani, F, Akutagava-Martins, GC, Cortese, S, Rohde, LA. Are ADHD medications under or over prescribed worldwide?: Protocol for a systematic review and meta-analysis. Medicine (Baltimore). 2018; 97(24): e10923.Google Scholar
Cortese, S, Moreira-Maia, CR, St Fleur, D, Morcillo-Peñalver, C, Rohde, LA, Faraone, SV. Association between ADHD and obesity: a systematic review and meta-analysis. Am J Psychiatry. 2016; 173(1): 34–43.CrossRefGoogle ScholarPubMed
Khalife, N, Kantomaa, M, Glover, V, Tammelin, T, Laitinen, J, Ebeling, H, et al. Childhood attention-deficit/hyperactivity disorder symptoms are risk factors for obesity and physical inactivity in adolescence. J Am Acad Child Adolesc Psychiatry. 2014; 53(4): 425–36.Google Scholar
Cortese, S, Tessari, L. Attention-deficit/hyperactivity disorder (ADHD) and obesity: update 2016. Curr Psychiatry Rep. 2017; 19(1): 4.Google Scholar
Albayrak, Ö, Pütter, C, Volckmar, A-L, Cichon, S, Hoffmann, P, Nöthen, MM, et al. Common obesity risk alleles in childhood attention-deficit/hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet. 2013; 162B(4): 295–305.Google Scholar
Choudhry, Z, Sengupta, SM, Grizenko, N, Thakur, GA, Fortier, M-E, Schmitz, N, Joober, R. Association between obesity-related gene FTO and ADHD. Obesity (Silver Spring). 2013; 21(12): E738–44.CrossRefGoogle ScholarPubMed
Berkman, N, Brownley, K, Peat, CEA. Management and Outcomes of Binge-Eating Disorder. Agency for Healthcare Research and Quality, 2015.Google ScholarPubMed
Brownley, KA, Berkman, ND, Peat, CM, Lohr, KN, Cullen, KE, Bann, CM, Bulik, CM. Binge-eating disorder in adults: a systematic review and meta-analysis. Ann Intern Med. 2016; 165(6): 409–20.CrossRefGoogle ScholarPubMed
Bruce, B, Wilfley, D. Binge eating among the overweight population: a serious and prevalent problem. J Am Diet Assoc. 1996; 96(1): 58–61.Google Scholar
McCuen-Wurst, C, Ruggieri, M, Allison, KC. Disordered eating and obesity: associations between binge-eating disorder, night-eating syndrome, and weight-related comorbidities. Ann N Y Acad Sci. 2018; 1411(1): 96–105.CrossRefGoogle ScholarPubMed
Haedt-Matt, AA, Keel, PK. Revisiting the affect regulation model of binge eating: a meta-analysis of studies using ecological momentary assessment. Psychol Bull. 2011; 137(4): 660–81.Google Scholar
Pearl, RL, Allison, KC, Tronieri, JS, Wadden, TA. Reconsidering the psychosocial–behavioral evaluation required prior to bariatric surgery. Obesity (Silver Spring). 2018; 26(2): 249–50.CrossRefGoogle ScholarPubMed
Devlin, MJ, Yanovski, SZ, Wilson, GT. Obesity: what mental health professionals need to know. Am J Psychiatry. 2000; 157(6): 854–66.CrossRefGoogle ScholarPubMed
Sarwer, DB, Wadden, TA, Fabricatore, AN. Psychosocial and behavioral aspects of bariatric surgery. Obes Res. 2005; 13(4): 639–48.CrossRefGoogle ScholarPubMed
Bauchowitz, A, Azarbad, L, Day, K, Gonder-Frederick, L. Evaluation of expectations and knowledge in bariatric surgery patients. Surg Obes Relat Dis. 2007; 3(5): 554–8.CrossRefGoogle ScholarPubMed
Walfish, S, Vance, D, Fabricatore, AN. Psychological evaluation of bariatric surgery applicants: procedures and reasons for delay or denial of surgery. Obes Surg. 2007; 17(12): 1578–83.CrossRefGoogle ScholarPubMed
Heymsfield, SB, Wadden, TA. Mechanisms, pathophysiology, and management of obesity. N Engl J Med. 2017; 376(15): 1492.Google Scholar
Jensen, MD, Ryan, DH, Apovian, CM, Ard, JD, Comuzzie, AG, Donato, KA, et al. 2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society. J Am Coll Cardiol. 2014; 63(25 Pt B): 2985–3023.Google Scholar
Lasikiewicz, N, Myrissa, K, Hoyland, A, Lawton, CL. Psychological benefits of weight loss following behavioural and/or dietary weight loss interventions. A systematic research review. Appetite. 2014; 72: 123–37.Google Scholar
Morledge, MD, Pories, WJ. Mental health in bariatric surgery: selection, access, and outcomes. Obesity (Silver Spring). 2020; 28(4): 689–95.Google Scholar
Fisher, D, Coleman, KJ, Arterburn, DE, Fischer, H, Yamamoto, A, Young, DR, et al. Mental illness in bariatric surgery: a cohort study from the PORTAL network. Obesity (Silver Spring). 2017; 25(5): 850–6.CrossRefGoogle ScholarPubMed
Orcutt, M, King, WC, Kalarchian, MA, Devlin, MJ, Marcus, MD, Garcia, L, et al. The relationship between childhood maltreatment and psychopathology in adults undergoing bariatric surgery. Surg Obes Relat Dis. 2019; 15(2): 295–303.Google Scholar
Faden, J, Leonard, D, O’Reardon, J, Hanson, R. Obesity as a defense mechanism. Int J Surg Case Rep. 2013; 4(1): 127–9.Google Scholar
Dawes, AJ, Maggard-Gibbons, M, Maher, AR, Booth, MJ, Miake-Lye, I, Beroes, JM, Shekelle, PG. Mental health conditions among patients seeking and undergoing bariatric surgery: a meta-analysis. JAMA. 2016; 315(2): 150–63.Google Scholar
Neovius, M, Bruze, G, Jacobson, P, Sjöholm, K, Johansson, K, Granath, F, et al. Risk of suicide and non-fatal self-harm after bariatric surgery: results from two matched cohort studies. Lancet Diabetes Endocrinol. 2018; 6(3): 197–207.CrossRefGoogle ScholarPubMed
Lagerros, YT, Brandt, L, Hedberg, J, Sundbom, M, Bodén, R. Suicide, self-harm, and depression after gastric bypass surgery: a nationwide cohort study. Ann Surg. 2017; 265(2): 235–43.CrossRefGoogle ScholarPubMed
King, WC, Chen, J-Y, Mitchell, JE, Kalarchian, MA, Steffen, KJ, Engel, SG, et al. Prevalence of alcohol use disorders before and after bariatric surgery. JAMA. 2012; 307(23): 2516–25.Google Scholar
King, WC, Chen, J-Y, Courcoulas, AP, Dakin, GF, Engel, SG, Flum, DR, et al. Alcohol and other substance use after bariatric surgery: prospective evidence from a U.S. multicenter cohort study. Surg Obes Relat Dis. 2017; 13(8): 1392–402.Google Scholar
Steffen, KJ, Engel, SG, Wonderlich, JA, Pollert, GA, Sondag, C. Alcohol and other addictive disorders following bariatric surgery: prevalence, risk factors and possible etiologies. Eur Eat Disord Rev. 2015; 23(6): 442–50.Google Scholar
Sogg, S. Comment on: Alcohol and other substance use after bariatric surgery: prospective evidence from a us multicenter cohort study. Surg Obes Relat Dis. 2017; 13(8): 1402–4.CrossRefGoogle ScholarPubMed

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