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8.5 - Physiological Support of the Organ Donor

from Section 8 - End-of-Life Care

Published online by Cambridge University Press:  27 July 2023

Ned Gilbert-Kawai
Affiliation:
The Royal Liverpool Hospital
Debashish Dutta
Affiliation:
Princess Alexandra Hospital NHS Trust, Harlow
Carl Waldmann
Affiliation:
Royal Berkshire Hospital, Reading
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Summary

Key Learning Points

  1. 1. Any patient likely to progress to brain death is a potential organ donor.

  2. 2. Severe raised intracranial pressure and brain death are associated with various organ system consequences.

  3. 3. Optimising the physiological status of a potential donor is an active process and may require escalation of monitoring and therapies.

  4. 4. Donor management improves the quality of donated organs.

  5. 5. Care bundles for the management of brain-dead organ donors are available.

Type
Chapter
Information
Intensive Care Medicine
The Essential Guide
, pp. 683 - 685
Publisher: Cambridge University Press
Print publication year: 2021

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References

References and Further Reading

Gordon, JK, McKinlay, J. Physiological changes after brain stem death and management of the heart-beating donor. Contin Educ Anaesth Crit Care Pain 2012;12:225–9.CrossRefGoogle Scholar
McKeown, DW, Bonser, RS, Kellum, JA. Management of the heartbeating brain-dead organ donor. Br J Anaesth 2012;108(Suppl 1):96107.CrossRefGoogle ScholarPubMed
NHS Blood and Transplant. Donor optimisation – guidance around selecting potential DBD donors. www.odt.nhs.uk/deceased-donation/best-practice-guidance/donor-optimisation/Google Scholar
NHS Blood and Transplant. 2012. Organ retrieval from donation after brain-stem death (DBD) donors in the UK. Donor Optimisation Extended Care Bundle. www.odt.nhs.uk/deceased-donation/best-practice-guidance/donor-optimisation/Google Scholar
Office of the Chief Health Officer, Ministry of Health NSW. 2016. Management of the adult brain dead potential organ and tissue donor. www1.health.nsw.gov.au/pds/ActivePDSDocuments/GL2016_008.pdfGoogle Scholar

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