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Chapter 4 - Structural Connectivity of the Insula

from Section 1 - The Human Insula from an Epileptological Standpoint

Published online by Cambridge University Press:  09 June 2022

By
Jimmy Ghaziri ,
Phillip Fei ,
Laurent Petit  and
Dang Khoa Nguyen
Edited by
Dang Nguyen ,
Jean Isnard  and
Philippe Kahane
Dang Nguyen
Affiliation:
Université de Montréal
Jean Isnard
Affiliation:
Claude Bernard University Lyon
Philippe Kahane
Affiliation:
Grenoble-Alpes University Hospital
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Summary

The insular cortex is an extensively connected brain region that has recently gained considerable interest due to its elusive role in several pathological conditions and its involvement in a variety of functions. Structural connectivity studies have identified connections to the frontal, temporal, and parietal cortices, with both a rostro-caudal and a dorso-ventral organizational pattern. The insula is also widely connected to subcortical structures. The use of diffusion-weighted imaging in insular epilepsy has not yet reached its full potential; however, it may still provide some insights into its pathophysiology, assess long-term consequences, and help prevent operative complications. This chapter explores the insula’s structural connectivity and promising applications in the field of insular epilepsy.

Keywords

insulainsular cortexconnectivitycorticalsubcorticalstructuralconnectionstractographydiffusion-weighteddiffusion tensorneuroanatomy
Type
Chapter
Information
Insular Epilepsies , pp. 31 - 39
Publisher: Cambridge University Press
Print publication year: 2022

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