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Chapter 5 - The Role of Estrogens in Pregnancy

from Section I - Hormones in the Physiology and Pharmacology of Pregnancy

Published online by Cambridge University Press:  09 November 2022

By
Nadia Berkane ,
Yveline Ansaldi  and
Nicola Pluchino
Edited by
Felice Petraglia ,
Mariarosaria Di Tommaso  and
Federico Mecacci
Felice Petraglia
Affiliation:
Università degli Studi, Florence
Mariarosaria Di Tommaso
Affiliation:
Università degli Studi, Florence
Federico Mecacci
Affiliation:
Università degli Studi, Florence
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Summary

Estrogens are essential during pregnancy and their importance stems from their role in the development and maturation of trophoblast cells and remodeling of uterine arteries, through the spreading and migration of invasive cytotrophoblast, angiogenesis and the lowering of uterine vasculature resistance. Dysregulation of estrogen synthesis may lead to pathological conditions such as preeclampsia or pre-term labor.

Type
Chapter
Information
Hormones and Pregnancy
Basic Science and Clinical Implications
 , pp. 42 - 49
Publisher: Cambridge University Press
Print publication year: 2022

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