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Chapter 15 - Adrenal Disease in Pregnancy

from Section II - Hormones and Gestational Disorders

Published online by Cambridge University Press:  09 November 2022

By
Jack Lockett ,
Warrick Inder ,
David H. McIntyre ,
Helen L. Barrett ,
Sailesh Kumar  and
Vicki Lee Clifton
Edited by
Felice Petraglia ,
Mariarosaria Di Tommaso  and
Federico Mecacci
Felice Petraglia
Affiliation:
Università degli Studi, Florence
Mariarosaria Di Tommaso
Affiliation:
Università degli Studi, Florence
Federico Mecacci
Affiliation:
Università degli Studi, Florence
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Summary

Through hormonal secretion, the adrenal gland regulates cellular homeostasis, stress, inflammation, metabolism, salt and water balance, and reproductive function amongst other systems. During pregnancy, significant changes occur in adrenal hormonal homeostasis, impacting the usual methods for evaluating adrenal disease. We summarize the changes to adrenal physiology occurring throughout pregnancy. Additionally, we discuss a range of adrenal diseases, their clinical assessment and management in pregnancy: adrenal insufficiency, congenital adrenal hyperplasia, Cushing’s syndrome, primary aldosteronism, pheochromocytoma, and adrenocortical carcinoma.

Type
Chapter
Information
Hormones and Pregnancy
Basic Science and Clinical Implications
 , pp. 164 - 182
Publisher: Cambridge University Press
Print publication year: 2022

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