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Section 9 - New Research and Technologies

Published online by Cambridge University Press:  27 March 2021

Jacques Donnez
Affiliation:
Catholic University of Louvain, Brussels
S. Samuel Kim
Affiliation:
University of Kansas School of Medicine
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Chapter
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Fertility Preservation
Principles and Practice
, pp. 381 - 432
Publisher: Cambridge University Press
Print publication year: 2021

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References

References

Donnez, J, Dolmans, MM. Fertility preservation in women. N Engl J Med, 2017;377:16571665.Google Scholar
Dolmans, MM, Masciangelo, R. Risk of transplanting malignant cells in cryopreserved ovarian tissue. Minerva Ginecol, 2018;70:436443.Google ScholarPubMed
Rodgers, RJ, Irving-Rodgers, HF, Russell, DL. Extracellular matrix of the developing ovarian follicle. Reproduction, 2003;126:415424.Google Scholar
Newton, H, Aubard, Y, Rutherford, A, Sharma, V, Gosden, R. Low temperature storage and grafting of human ovarian tissue. Hum Reprod, 1996;11:14871491.Google Scholar
Aubard, Y, Piver, P, Cogni, Y et al. Orthotopic and heterotopic autografts of frozen-thawed ovarian cortex in sheep. Hum Reprod, 1999;14:21492154.Google Scholar
Baird, DT, Webb, R, Campbell, BK, Harkness, LM, Gosden, RG. Long-term ovarian function in sheep after ovariectomy and transplantation of autografts stored at -196°C. Endocrinology, 1999;140:462471.Google Scholar
Dath, C, Dethy, A, Van Langendonckt, A et al. Endothelial cells are essential for ovarian stromal tissue restructuring after xenotransplantation of isolated ovarian stromal cells. Hum Reprod, 2011;26:14311439.Google Scholar
Soares, M, Sahrari, K, Chiti, MC et al. The best source of isolated stromal cells for the artificial ovary: medulla or cortex, cryopreserved or fresh? Hum Reprod, 2015;30:15891598.CrossRefGoogle ScholarPubMed
Loh, QL, Choong, C. Three-dimensional scaffolds for tissue engineering applications: role of porosity and pore size. Tissue Eng Part B Rev, 2013;19:485502.Google Scholar
Sun, H, Wang, X, Hu, X et al. Promotion of angiogenesis by sustained release of rhGM-CSF from heparinized collagen/chitosan scaffolds. J Biomed Mater Res B Appl Biomater, 2012;100:788798.Google Scholar
Jiang, X, Lin, H, Jiang, D et al. Co-delivery of VEGF and bFGF via a PLGA nanoparticle-modified BAM for effective contracture inhibition of regenerated bladder tissue in rabbits. Sci Rep, 2016;6:20784.CrossRefGoogle Scholar
Peters, A, Baruch, Y, Weisbuch, F et al. Enhancing the vascularization of three-dimensional porous alginate by incorporating controlled release basic fibroblast growth factor microspheres. J Biomed Mater Res A, 2003;65:489497.Google Scholar
Bergmann, NM, West, JL. Histogenesis in three-dimensional scaffolds. In Atala, A, Lanza, R, Thomson, JA, Nerem, RM (eds.) Principles of Regenerative Medicine. Burlington, VT: Academic Press. 2008, 686703.CrossRefGoogle Scholar
Gigli, I, Cushman, RA, Wahl, CM, Fortune, FE. Evidence for a role for anti-Mullerian hormone in the suppression of follicle activation in mouse ovaries and bovine ovarian cortex grafted beneath the chick chorioallantoic membrane. Mol Reprod Dev, 2005;71:480488.Google Scholar
Camboni, A, Martinez-Madrid, B, Dolmans, MM et al. Autotransplantation of frozen-thawed ovarian tissue in a young woman: ultrastructure and viability of grafted tissue. Fertil Steril, 2008;90:12151218.CrossRefGoogle Scholar
Keros, V, Xella, S, Hultenby, K et al. Vitrification versus controlled-rate freezing in cryopreservation of human ovarian tissue. Hum Reprod, 2009;24:16701683.Google Scholar
Nisolle, M, Casanas-Roux, F, Qu, J, Motta, P, Donnez, J. Histologic and ultrastructural evaluation of fresh and frozen-thawed human ovarian xenografts in nude mice. Fertil Steril, 2000;74:122129.Google Scholar
Nottola, SA, Camboni, A, Van Langendonckt, A et al. Cryopreservation and xenotransplantation of human ovarian tissue: an ultrastructural study. Fertil Steril, 2008;90:2332.CrossRefGoogle ScholarPubMed
Amorim, CA, Van Langendonckt, A, David, A, Dolmans, MM, Donnez, J. Survival of human pre-antral follicles after cryopreservation of ovarian tissue, follicular isolation and in vitro culture in a calcium alginate matrix. Hum Reprod, 2009;24:9299.Google Scholar
Laschke, MW, Menger, MD, Vollmar, B. Ovariectomy improves neovascularisation and microcirculation of freely transplanted ovarian follicles. J Endocrinol, 2002;172:535544.Google Scholar
Amorim, CA, Gonçalves, PB, Figueiredo, JR. Cryopreservation of oocytes from pre-antral follicles. Hum Reprod Update, 2003;9:119129.Google Scholar
Irving-Rodgers, HF, Morris, S, Collett, RA et al. Phenotypes of the ovarian follicular basal lamina predict developmental competence of oocytes. Hum Reprod, 2009;24:936944.Google Scholar
Telfer, EE, McLaughlin, M, Ding, C, Thong, KJ. A two-step serum free culture system supports development of human oocytes from primordial follicles in the presence of activing. Hum Reprod, 2008;23:11511158.Google Scholar
Dolmans, MM, Michaux, N, Camboni, A et al. Evaluation of Liberase, a purified enzyme blend, for the isolation of human primordial and primary ovarian follicles. Hum Reprod, 2006;21:413420.Google Scholar
Lierman, S, Tilleman, K, Cornelissen, M et al. Follicles of various maturation stages react differently to enzymatic isolation: a comparison of different isolation protocols. Reprod Biomed Online, 2015;30:181190.Google Scholar
Rice, S, Ojha, K, Mason, H. Human ovarian biopsies as a viable source of pre-antral follicles. Hum Reprod, 2008;23:600605.CrossRefGoogle ScholarPubMed
Chiti, MC, Donnez, J, Amorim, CA, Dolmans, MM. From isolation of human ovarian follicles to the artificial ovary: tips and tricks. Minerva Ginecol, 2018;70:444455.Google Scholar
Kristensen, SG, Rasmussen, A, Byskov, AG, Andersen, CY. Isolation of pre-antral follicles from human ovarian medulla tissue. Hum Reprod, 2011;26:157166.Google Scholar
Schmidt, KL, Byskov, AG, Nyboe Andersen, A et al. Density and distribution of primordial follicles in single pieces of cortex from 21 patients and in individual pieces of cortex from three entire human ovaries. Hum Reprod, 2003;18:11581164.Google Scholar
Vanacker, J, Camboni, A, Dath, C et al. Enzymatic isolation of human primordial and primary ovarian follicles with Liberase DH: protocol for application in a clinical setting. Fertil Steril, 2011;96:379–383.e3.CrossRefGoogle ScholarPubMed
Chiti, MC, Dolmans, MM, Hobeika, M et al. A modified and tailored human follicle isolation procedure improves follicle recovery and survival. J Ovarian Res, 2017;10:71.Google Scholar
Paulini, F, Vilela, JM, Chiti, MC et al. Survival and growth of human preantral follicles after cryopreservation of ovarian tissue, follicle isolation and short-term xenografting. Reprod Biomed Online, 2016;33:425432.Google Scholar
Soares, M, Sahrari, K, Amorim, CA et al. Evaluation of a human ovarian follicle isolation technique to obtain disease-free follicle suspensions before safely grafting to cancer patients. Fertil Steril, 2015;104:672–680.e2.Google Scholar
Soares, M, Saussoy, P, Sahrari, K et al. Is transplantation of a few leukemic cells inside an artificial ovary able to induce leukemia in an experimental model? J Assist Reprod Genet, 2015;32:597606.Google Scholar
Mouloungui, E, Zver, T, Roux, C, Amiot, C. A protocol to isolate and qualify purified human preantral follicles in cases of acute leukemia, for future clinical applications. J Ovarian Res, 2018;11:4.Google Scholar
Soares, M, Saussoy, P, Maskens, M et al. Eliminating malignant cells from cryopreserved ovarian tissue is possible in leukaemia patients. Br J Haematol, 2017;178:231239.Google Scholar
Von der Mark, K, Park, J, Bauer, S, Schmuki, P. Nanoscale engineering of biomimetic surfaces: cues from the extracellular matrix. Cell Tissue Res, 2010;339:131153.Google Scholar
Murray, AA, Gosden, RG, Allison, V, Spears, N. Effect of androgens on the development of mouse follicles growing in vitro. J Reprod Fertil, 1998;113:2733.Google Scholar
Reynaud, K, Cortvrindt, R, Smitz, J, Driancourt, MA. Effects of Kit Ligand and anti-Kit antibody on growth of cultured mouse preantral follicles. Mol Reprod Dev, 2000;56:483494.Google Scholar
Picton, HM, Gosden, RG. In vitro growth of human primordial follicles from frozen-banked ovarian tissue. Mol Cell Endocrinol, 2000;166:2735.Google Scholar
Xu, M, Kreeger, PK, Shea, LD, Woodruff, TK. Tissue-engineered follicles produce live, fertile offspring. Tissue Eng, 2006;12:27392746.CrossRefGoogle ScholarPubMed
Xu, M, Barrett, SL, West-Farrell, E et al. In vitro grown human ovarian follicles from cancer patients support oocyte growth. Hum Reprod, 2009;24:25312540.Google Scholar
West, ER, Shea, LD, Woodruff, TK. Engineering the follicle microenvironment. Semin Reprod Med, 2007;25:287299.Google Scholar
Chan, BP, Leong, KW. Scaffolding in tissue engineering: general approaches and tissue-specific considerations. Eur Spine J, 2008;17:467479.Google Scholar
Kim, J, Perez, AS, Claflin, J et al. Synthetic hydrogel supports the function and regeneration of artificial ovarian tissue in mice. NPJ Regen Med, 2016;1:16010.Google Scholar
Day, JR, David, A, Cichon, AL et al. Immunoisolating poly(ethylene glycol) based capsules support ovarian tissue survival to restore endocrine function. J Biomed Mater Res A, 2018;106:13811389.Google Scholar
Mendez, U, Zhou, H, Shikanov, A. Synthetic PEG hydrogel for engineering the environment of ovarian follicles. Methods Mol Biol, 2018;1758:115128.Google Scholar
Gubeli, RJ, Laird, D, Ehrabar, M et al. Pharmacologically tunable polyethylene-glycol-based cell growth substrate. Acta Biomater, 2013;9:82728278.Google Scholar
Telfer, EC, Torrance, C, Gosden, RG. Morphological study of cultured preantral ovarian follicles of mice after transplantation under the kidney capsule. J Reprod Fertil, 1990, 89:565571.Google Scholar
Gosden, RG. Restitution of fertility in sterilized mice by transferring primordial ovarian follicles. Hum Reprod, 1990;5:499504.Google Scholar
Vanacker, J, Amorim, CA. Alginate: a versatile biomaterial to encapsulate isolated ovarian follicles. Ann Biomed Eng, 2017;45:16331649.Google Scholar
Chiti, MC, Dolmans, MM, Donnez, J, Amorim, CA. Fibrin in reproductive tissue engineering: a review on its application as a biomaterial for fertility preservation. Ann Biomed Eng, 2017;45:16501663.Google Scholar
Laronda, MM, Rutz, AL, Xiao, S et al. A bioprosthetic ovary created using 3D printed microporous scaffolds restores ovarian function in sterilized mice. Nat Commun, 2017;8:15261.Google Scholar
Chiti, MC. Fertility preservation in cancer patients: development of a transplantable artificial ovary protoype, in Pôle de Recherche en Gynécologie. 2017, Université Catholique de Louvain.Google Scholar
Carroll, J, Gosden, RG. Transplantation of frozen-thawed mouse primordial follicles. Hum Reprod, 1993;8:11631167.Google Scholar
Dolmans, MM, Martinez-Madrid, B, Gadisseux, E et al. Short-term transplantation of isolated human ovarian follicles and cortical tissue into nude mice. Reproduction, 2007;134:253262.Google Scholar
Dolmans, MM, Yuan, WY, Camboni, A et al. Development of antral follicles after xenografting of isolated small human preantral follicles. Reprod Biomed Online, 2008;16:705711.Google Scholar
Vanacker, J, Luyckx, V, Dolmans, MM et al. Transplantation of an alginate-matrigel matrix containing isolated ovarian cells: first step in developing a biodegradable scaffold to transplant isolated preantral follicles and ovarian cells. Biomaterials, 2012;33:60796085.Google Scholar
Vanacker, J, Dolmans, MM, Luyckx, V, Donnez, J, Amorim, CA. First transplantation of isolated murine follicles in alginate. Regen Med, 2014;9:609619.Google Scholar
Van Eyck, AS, Jordan, BF, Gallez, B et al. Electron paramagnetic resonance as a tool to evaluate human ovarian tissue reoxygenation after xenografting. Fertil Steril, 2009;92:374381.Google Scholar
Luyckx, V, Dolmans, MM, Vanacker, J et al. First step in developing a 3D biodegradable fibrin scaffold for an artificial ovary. J Ovarian Res, 2013;6:83.Google Scholar
Luyckx, V, Dolmans, MM, Vanacker, J et al. A new step toward the artificial ovary: survival and proliferation of isolated murine follicles after autologous transplantation in a fibrin scaffold. Fertil Steril, 2014;101:11491156.Google Scholar
Kniazeva, E, Hardy, AN, Boukaidi, SA et al. Primordial follicle transplantation within designer biomaterial grafts produce live births in a mouse infertility model. Sci Rep, 2015;5:17709.Google Scholar
Chiti, MC, Dolmans, MM, Orellana, R et al. Influence of follicle stage on artificial ovary outcome using fibrin as a matrix. Hum Reprod, 2016;31:427435.CrossRefGoogle ScholarPubMed
Chiti, MC, Dolmans, MM, Lucci, CM et al. Further insights into the impact of mouse follicle stage on graft outcome in an artificial ovary environment. Mol Hum Reprod, 2017;23:381392.Google Scholar
Chiti, MC, Dolmans, MM, Mortiaux, L et al. A novel fibrin-based artificial ovary prototype resembling human ovarian tissue in terms of architecture and rigidity. J Assist Reprod Genet, 2018;35:4148.Google Scholar
Chiti, MC, Viswanath, A, Vanacker, J et al. Hydrogel from bovine decellularized ovarian extracellular matrix supports mouse follicle survival in vitro. Front Bioeng Biotechnol, 2016;14:273.Google Scholar
Laronda, MM, Jakus AE, Whelan KA et al. Initiation of puberty in mice following decellularized ovary transplant. Biomaterials, 2015;50:2029.Google Scholar
Liu, WY, Lin, SG, Zhuo, RY et al. Xenogeneic decellularized scaffold: a novel platform for ovary regeneration. Tissue Eng Part C Methods, 2017;23:6171.Google Scholar
Jakus, AE, Laronda, MM, Rashedi, AS et al. “Tissue papers” from organ-specific decellularized extracellular matrices. Adv Funct Mater, 2017;27.Google Scholar
Ouni, E, Vertommen, D, Chiti, MC, Dolmans, MM, Amorim, CA. A draft map of the human ovarian proteome for tissue engineering and clinical applications. Mol Cell Proteomics, 2018;18(Suppl 1):S159S173.Google Scholar
Knight, PG, Glister, C. TGF-beta superfamily members and ovarian follicle development. Reproduction, 2006;132:191206.Google Scholar
Orisaka, M, Tajima, K, Mizutani, T et al. Granulosa cells promote differentiation of cortical stromal cells into theca cells in the bovine ovary. Biol Reprod, 2006;75:734740.Google Scholar
Honda, A, Hirose, M, Hara, K et al. Isolation, characterization, and in vitro and in vivo differentiation of putative thecal stem cells. Proc Natl Acad Sci U S A, 2007;104:1238912394.Google Scholar
Itoh, T, Kacchi, M, Abe, H, Sendai, Y, Hoshi, H. Growth, antrum formation, and estradiol production of bovine preantral follicles cultured in a serum-free medium. Biol Reprod, 2002;67:10991105.Google Scholar
Tagler, D, Tu, T, Smith, RM et al. Embryonic fibroblasts enable the culture of primary ovarian follicles within alginate hydrogels. Tissue Eng Part A, 2012;18:12291238.Google Scholar
Telfer, EE, Zelinski, MB. Ovarian follicle culture: advances and challenges for human and nonhuman primates. Fertil Steril, 2013;99:15231533.Google Scholar
Schröder, CP, Timmer-Bosscha, H, Wijchman, JG et al. An in vitro model for purging of tumour cells from ovarian tissue. Hum Reprod, 2004;19:10691075.Google Scholar
Meirow, D, Dor, J, Kaufman, B et al. Cortical fibrosis and blood-vessels damage in human ovaries exposed to chemotherapy. Potential mechanisms of ovarian injury. Hum Reprod, 2007;22:16261633.Google Scholar
Soares, M. Fertility preservation and leukemia: cellular components of the artificial ovary and disease retransmission through the graft, in Pôle de Recherche en Gynécologie. 2015, Université Catholique de Louvain.Google Scholar
Donnez, J, Dolmans, MM, Pellicer, A et al. Restoration of ovarian activity and pregnancy after transplantation of cryopreserved ovarian tissue: a review of 60 cases of reimplantation. Fertil Steril, 2013;99:15031513.Google Scholar
Schmidt, VM, Isachenko, V, Rappl, G et al. Comparison of the enzymatic efficiency of Liberase TM and tumor dissociation enzyme: effect on the viability of cells digested from fresh and cryopreserved human ovarian cortex. Reprod Biol Endocrinol, 2018;16:57.Google Scholar
Chiti, MC, Dolmans, MM, Donnez, J, Amorim, CA. A fibrin based artificial ovary prototype: from animal studies to human clinical application. Curr Trends Clin Embryol submitted.Google Scholar

References

Brannstrom, M, Johannesson, L, Bokstrom, H et al. Livebirth after uterus transplantation. Lancet, 2015;385:607616.Google Scholar
Brannstrom, M, Bokstrom, H, Dahm-Kahler, P et al. One uterus bridging three generations: first live birth after mother-to-daughter uterus transplantation. Fertil Steril, 2016;106(2):261266.Google Scholar
Testa, G, McKenna, GJ, Gunby, RT Jr. et al. First live birth after uterus transplantation in the United States. Am J Transplant, 2018;18:12701274.Google Scholar
Sieunarine, K, Zakaria, FB, Boyle, DC et al. Possibilities for fertility restoration: a new surgical technique. Int Surg, 2005;90:249256.Google Scholar
Oppelt, P, Renner, SP, Kellermann, A et al. Clinical aspects of Mayer-Rokitansky-Kuester-Hauser syndrome: recommendations for clinical diagnosis and staging. Hum Reprod, 2006;21:792797.Google Scholar
Oppelt, PG, Lermann, J, Strick, R et al. Malformations in a cohort of 284 women with Mayer-Rokitansky-Kuster-Hauser syndrome (MRKH). Reprod Biol Endocrinol, 2012;10:57.Google Scholar
Brannstrom, M, Diaz-Garcia, C, Johannesson, L et al. Livebirth after uterus transplantation – Authors’ reply. Lancet, 2015;385:23522353.Google Scholar
Chan, YY, Jayaprakasan, K, Tan, A et al. Reproductive outcomes in women with congenital uterine anomalies: a systematic review. Ultrasound Obstet Gynecol, 2011;38:371382.Google Scholar
Fernandez, H, Al-Najjar, F, Chauveaud-Lambling, A et al. Fertility after treatment of Asherman’s syndrome stage 3 and 4. J Minim Invasive Gynecol, 2006;13:398402.Google Scholar
Brannstrom, M, Diaz-Garcia, C, Hanafy, A et al. Uterus transplantation: animal research and human possibilities. Fertil Steril, 2012;97:12691276.Google Scholar
Moore, FD. Ethical problems special to surgery: surgical teaching, surgical innovation, and the surgeon in managed care. Arch Surg, 2000;135:1416.Google Scholar
McCulloch, P, Altman, DG, Campbell, WB et al. No surgical innovation without evaluation: the IDEAL recommendations. Lancet, 2009;374:11051112.Google Scholar
Racho El-Akouri, R, Kurlberg, G, Dindelegan, G et al. Heterotopic uterine transplantation by vascular anastomosis in the mouse. J Endocrinol, 2002;174:157166.Google Scholar
Racho El-Akouri, R, Kurlberg, G, Brannstrom, M. Successful uterine transplantation in the mouse: pregnancy and post-natal development of offspring. Hum Reprod, 2003;18:20182023.Google Scholar
Racho El-Akouri, R, Wranning, CA, Molne, J et al. Pregnancy in transplanted mouse uterus after long-term cold ischaemic preservation. Hum Reprod, 2003;18:20242030.Google Scholar
Wranning, CA, Akhi, SN, Diaz-Garcia, C, Brannstrom, M. Pregnancy after syngeneic uterus transplantation and spontaneous mating in the rat. Hum Reprod, 2011;26:553558.Google Scholar
Diaz-Garcia, C, Akhi, SN, Wallin, A et al. First report on fertility after allogeneic uterus transplantation. Acta Obstet Gynecol Scand, 2010;89:14911494.Google Scholar
Diaz-Garcia, C, Johannesson, L, Shao, R et al. Pregnancy after allogeneic uterus transplantation in the rat: perinatal outcome and growth trajectory. Fertil Steril, 2014;102:1545–1552 e1541.Google Scholar
Wranning, CA, Marcickiewicz, J, Enskog, A et al. Fertility after autologous ovine uterine-tubal-ovarian transplantation by vascular anastomosis to the external iliac vessels. Hum Reprod, 2010;25:19731979.Google Scholar
Ramirez, ER, Ramirez Nessetti, DK, Nessetti, MB et al. Pregnancy and outcome of uterine allotransplantation and assisted reproduction in sheep. J Minim Invasive Gynecol, 2011;18:238245.Google Scholar
Mihara, M, Kisu, I, Hara, H et al. Uterine autotransplantation in cynomolgus macaques: the first case of pregnancy and delivery. Hum Reprod, 2012;27:23322340.Google Scholar
Fageeh, W, Raffa, H, Jabbad, H, Marzouki, A. Transplantation of the human uterus. Int J Gynaecol Obstet, 2002;76:245251.Google Scholar
Jarvholm, S, Johannesson, L, Brannstrom, M. Psychological aspects in pre-transplantation assessments of patients prior to entering the first uterus transplantation trial. Acta Obstet Gynecol Scand, 2015;94:10351038.Google Scholar
Brannstrom, M, Johannesson, L, Dahm-Kahler, P et al. First clinical uterus transplantation trial: a six-month report. Fertil Steril, 2014;101:12281236.Google Scholar
Jarvholm, S, Johannesson, L, Clarke, A, Brannstrom, M. Uterus transplantation trial: Psychological evaluation of recipients and partners during the post-transplantation year. Fertil Steril, 2015;104:10101015.Google Scholar
Kvarnstrom, N, Jarvholm, S, Johannesson, L et al. Live donors of the initial observational study of uterus transplantation-psychological and medical follow-up until 1 year after surgery in the 9 cases. Transplantation, 2017;101:664670.Google Scholar
Blume, C, Pischke, S, von Versen-Hoynck, F et al. Pregnancies in liver and kidney transplant recipients: a review of the current literature and recommendation. Best Pract Res Clin Obstet Gynaecol, 2014;28:11231136.Google Scholar
Molne, J, Broecker, V, Ekberg, J et al. Monitoring of human uterus transplantation with cervical biopsies: a provisional scoring system for rejection. Am J Transplant, 2017;17:16281636.Google Scholar
Brannstrom, M, Bokstrom, H, Dahm-Kahler, P et al. One uterus bridging three generations: first live birth after mother-to-daughter uterus transplantation. Fertil Steril, 2016;106:261266.Google Scholar
Wei, L, Xue, T, Tao, KS et al. Modified human uterus transplantation using ovarian veins for venous drainage: the first report of surgically successful robotic-assisted uterus procurement and follow-up for 12 months. Fertil Steril, 2017;108:346–356 e341.Google Scholar
Shuster, LT, Gostout, BS, Grossardt, BR, Rocca, WA. Prophylactic oophorectomy in premenopausal women and long-term health. Menopause Int, 2008;14:111116.Google Scholar
Chmel, R, Novackova, M, Janousek, L et al. Revaluation and lessons learned from the first nine cases of a Czech uterus transplantation trial: four deceased donor and five living donor uterus transplantations. Am J Transplant, 2019;19(3):855864.CrossRefGoogle Scholar
Brucker, SY, Brannstrom, M, Taran, FA et al. Selecting living donors for uterus transplantation: lessons learned from two transplantations resulting in menstrual functionality and another attempt, aborted after organ retrieval. Arch Gynecol Obstet, 2018;297(3):675684.Google Scholar
Testa, G, Koon, EC, Johannesson, L et al. Living donor uterus transplantation: a single center’s observations and lessons learned from early setbacks to technical success. Am J Transplant, 2017;17:29012910.CrossRefGoogle ScholarPubMed
Puntambekar, S, Telang, M, Kulkarni, P et al. Laparoscopic-assisted uterus retrieval from live organ donors for uterine transplant: our experience of two patients. J Minim Invasive Gynecol, 2018;25:622631.Google Scholar
Ozkan, O, Akar, ME, Ozkan, O et al. Preliminary results of the first human uterus transplantation from a multiorgan donor. Fertil Steril, 2013;99:470476.Google Scholar
Flyckt, RL, Farrell, RM, Perni, UC et al. Deceased donor uterine transplantation: innovation and adaptation. Obstet Gynecol, 2016;128:837842.Google Scholar
Ejzenberg, D, Andraus, W, Baratelli Carelli, Mendes LR et al. Livebirth after uterus transplantation from a deceased donor in a recipient with uterine infertility. Lancet, 2019;392:26972704.Google Scholar
Miravet-Valenciano, JA, Rincon-Bertolin, A, Vilella, F, Simon, C. Understanding and improving endometrial receptivity. Curr Opin Obstet Gynecol, 2015;27:187192.Google Scholar
Wranning, CA, Molne, J, El-Akouri, RR et al. Short-term ischaemic storage of human uterine myometrium–basic studies towards uterine transplantation. Hum Reprod, 2005;20:27362744.Google Scholar
Tricard, J, Ponsonnard, S, Tholance, Y et al. Uterus tolerance to extended cold ischemic storage after auto-transplantation in ewes. Eur J Obstet Gynecol Reprod Biol, 2017;214:162167.Google Scholar
Erman Akar, M, Ozkan, O, Aydinuraz, B et al. Clinical pregnancy after uterus transplantation. Fertil Steril, 2013;100:13581363.Google Scholar
Johannesson, L, Enskog, A, Molne, J et al. Preclinical report on allogeneic uterus transplantation in non-human primates. Hum Reprod, 2013;28:189198.Google Scholar

References

Kocher, T. Ueber die Bedingungen erfolgreicher Schilddrüsentransplantation beim Menschen: A. Hirschwald, 1914.Google Scholar
Jaffe, HL. On the transplantation of the guinea pig suprarenal and the functioning of the grafts. J Exp Med, 1927;45:587594.Google Scholar
Berthold, A. Transplantation der Hoden. Mueller’s Arch f Exper Med, 1849:92.Google Scholar
Knauer, E. Einige Versuche über Ovarientransplantation bei Kaninchen. Centralblatt f Gynaekologie, 1896;20:524528.Google Scholar
Bert, P. De la greffe animale 1863:4849.Google Scholar
Morris, RT. The ovarian graft. New York Medical Journal, 1895;62:436.Google Scholar
Harris, M, Eakin, RM. Survival of transplanted ovaries in rats. J Exp Zool, 1949;112:131163, incl 3 pl.Google Scholar
Green, CJ, Simpkin, S, Grimaldi, G, Johnson, A. Pregnancy after autografting and allografting vascularized ovaries and en bloc vascularized ovaries with adnexa in rabbits. Br J Obstet Gynaecol 1982;89:645651.CrossRefGoogle ScholarPubMed
Scott, JR, Hendrickson, M, Lash, S, Shelby, J. Pregnancy after tubo-ovarian transplantation. Obstet Gynecol, 1987;70:229234.Google Scholar
Carmona, F, Balasch, J, Gonzalez-Merlo, J. Ovarian function, tubal viability and pregnancy after tubo-ovarian transplantation in the rabbit. Hum Reprod, 1993;8:929931.Google Scholar
Meraz, MM, Juarez, CG, Monsalve, CR et al. Restoration of endocrine function and fertility with orthotopic tubal-ovarian allotransplant as the anatomical-functional unit in rabbits. J Invest Surg: The Official Journal of the Academy of Surgical Research, 2008;21:348359.Google Scholar
Alberti, LR, Vasconcellos Lde, S, Petroianu, A. Autologous and allogeneic ovarian orthotopic transplantation: morphologic, endocrinologic and natural pregnancy assessment. Acta Cir Bras, 2013;28:5965.Google Scholar
Silber, SJ, Lenahan, KM, Levine, DJ et al. Ovarian transplantation between monozygotic twins discordant for premature ovarian failure. N Engl J Med, 2005;353:5863.Google Scholar
Silber, SJ, Gosden, RG. Ovarian transplantation in a series of monozygotic twins discordant for ovarian failure. N Engl J Med, 2007;356:13821384.Google Scholar
Donnez, J, Dolmans, MM, Pirard, C et al. Allograft of ovarian cortex between two genetically non-identical sisters: case report. Hum Reprod, 2007;22:26532659.Google Scholar
Donnez, J, Squifflet, J, Pirard, C, Jadoul, P, Dolmans, MM. Restoration of ovarian function after allografting of ovarian cortex between genetically non-identical sisters. Hum Reprod, 2010;25:24892495.Google Scholar
Donnez, J, Squifflet, J, Pirard, C et al. Live birth after allografting of ovarian cortex between genetically non-identical sisters. Hum Reprod, 2011;26:13841388.Google Scholar
Donnez, J, Dolmans, MM, Squifflet, J, Kerbrat, G, Jadoul, P. Live birth after allografting of ovarian cortex between monozygotic twins with Turner syndrome (45,XO/46,XX mosaicism) and discordant ovarian function. Fertil Steril, 2011;96:14071411.Google Scholar
Mhatre, P, Mhatre, J, Magotra, R. Ovarian transplant: a new frontier. Transplant Proc, 2005;37:13961398.Google Scholar
Mhatre, P, Mhatre, J. Orthotopic ovarian transplant–review and three surgical techniques. Pediatr Transplant, 2006;10:782787.Google Scholar
Feichtinger, M, Barnea, ER, Nyachieo, A, Brannstrom, M, Kim, SS. Allogeneic ovarian transplantation using immunomodulator preimplantation factor (PIF) as monotherapy restored ovarian function in olive baboon. J Assist Reprod Genet, 2018;35:8189.Google Scholar
van der Schouw, YT, van der Graaf, Y, Steyerberg, EW, Eijkemans, JC, Banga, JD. Age at menopause as a risk factor for cardiovascular mortality. Lancet, 1996;347:714718.Google Scholar
Popat, VB, Calis, KA, Vanderhoof, VH et al. Bone mineral density in estrogen-deficient young women. J Clin Endocrinol Metab, 2009;94:22772283.Google Scholar
Schmidt, PJ, Luff, JA, Haq, NA et al. Depression in women with spontaneous 46, XX primary ovarian insufficiency. J Clin Endocrinol Metab, 2011;96:E278E287.Google Scholar
Sullivan, SD, Sarrel, PM, Nelson, LM. Hormone replacement therapy in young women with primary ovarian insufficiency and early menopause. Fertil Steril, 2016;106:15881599.Google Scholar
Asch, R, Balmaceda, J, Ord, T et al. Oocyte donation and gamete intrafallopian transfer as treatment for premature ovarian failure. Lancet, 1987;1:687.Google Scholar
Cabry, R, Merviel, P, Hazout, A et al. Management of infertility in women over 40. Maturitas, 2014;78:1721.Google Scholar
Yin, H, Wang, X, Kim, SS et al. Transplantation of intact rat gonads using vascular anastomosis: effects of cryopreservation, ischaemia and genotype. Hum Reprod, 2003;18:11651172.Google Scholar
Gosden, RG. Survival of ovarian allografts in an experimental animal model. Pediatr Transplant, 2007;11:628633.Google Scholar
Lind, T, Holte, J, Olofsson, JI et al. Reduced live-birth rates after IVF/ICSI in women with previous unilateral oophorectomy: results of a multicentre cohort study. Hum Reprod, 2018;33:238247.Google Scholar
Robertson, JA. Ethical issues in ovarian transplantation and donation. Fertil Steril, 2000;73:443446.Google Scholar

References

Borgmann-Staudt, A, Rendtorff, R, Reinmuth, S et al. Fertility after allogeneic haematopoietic stem cell transplantation in childhood and adolescence. Bone Marrow Transplant, 2011;47:271. DOI:10.1038/bmt.2011.78Google Scholar
Kalich-Philosoph, L, Roness, H, Carmely, A et al. Cyclophosphamide triggers follicle activation and “Burnout”; AS101 prevents follicle loss and preserves fertility. Sci Transl Med, 2013;5(185):185ra62. DOI:10.1126/scitranslmed.3005402.Google Scholar
Salooja, N, Szydlo, RM, Socie, G et al. Pregnancy outcomes after peripheral blood or bone marrow transplantation: a retrospective survey. Lancet, 2001;358(9278):271276. DOI:https://doi.org/10.1016/S0140-6736(01)05482-4Google Scholar
Lutchman Singh, K, Davies, M, Chatterjee, R. Fertility in female cancer survivors: pathophysiology, preservation and the role of ovarian reserve testing. Hum Reprod Update, 2005;11(1):6989. DOI:10.1093/humupd/dmh052Google Scholar
Silber, SJ, Lenahan, K, Levine, DJ et al. Ovarian transplantation between monozygotic twins discordant for premature ovarian failure. N Engl J Med, 2005;353(1):58–63. doi: 10.1056/NEJMoa043157.Google Scholar
Silber, SJ. Ovary cryopreservation and transplantation for fertility preservation. Mol Hum Reprod, 2012;18(2):5967. DOI:10.1093/molehr/gar082Google Scholar
Silber, S. How ovarian transplantation works and how resting follicle recruitment occurs: a review of results reported from one center. Women’s Health (Lond), 2016; 12(2): 217–227.Google Scholar
Silber, S, Kagawa, N, Kuwayama, M, Gosden, R. Duration of fertility after fresh and frozen ovary transplantation. Fertil Steril, 2010;94(6):21912196. DOI:https://doi.org/10.1016/j.fertnstert.2009.12.073Google Scholar
Donnez, J, Dolmans, M-M, Squifflet, J, Kerbrat, G, Jadoul, P. Live birth after allografting of ovarian cortex between monozygotic twins with Turner syndrome (45,XO/46,XX mosaicism) and discordant ovarian function. Fertil Steril, 2011;96(6):14071411. DOI:https://doi.org/10.1016/j.fertnstert.2011.09.012Google Scholar
Jadoul, P, Dolmans, MM, Donnez, J. Fertility preservation in girls during childhood: is it feasible, efficient and safe and to whom should it be proposed? Hum Reprod Update, 2010;16(6):617630. DOI:10.1093/humupd/dmq010Google Scholar
Borgström, B, Hreinsson, J, Rasmussen, C et al. Fertility preservation in girls with Turner syndrome: prognostic signs of the presence of ovarian follicles. J Clin Endocrinol Metabol, 2009;94(1):7480. DOI:10.1210/jc.2008-0708Google Scholar
Silber, SJ, Gosden, RG. Ovarian transplantation in a series of monozygotic twins discordant for ovarian failure. N Engl J Med, 2007;356(13):13821384. DOI:10.1056/NEJMc066574Google Scholar
Saitou, M, Payer, B, Lange, UC et al. Specification of germ cell fate in mice. Philos Trans R Soc Lond B Biol Sci, 2003;358(1436):136313670. DOI:10.1098/rstb.2003.1324Google Scholar
Lebl, J, Zahradníková, M, Vlasak, I, Neuhuber, F. Discordant growth pattern and ovarian function in monozygotic twins with 45,X/46,XX mosaicism. Horm Res Paediatr, 2001;55(2):102105.Google Scholar
Young, LE. Imprinting of genes and the barker hypothesis. Twin Res, 2012;4(5):307317. DOI:10.1375/twin.4.5.307Google Scholar
Hajkova, P, Erhardt, S, Lane, N et al. Epigenetic reprogramming in mouse primordial germ cells. Mech Dev, 2002;117(1):1523. DOI:https://doi.org/10.1016/S0925-4773(02)00181-8Google Scholar
Donnez, J, Silber, S, Andersen, CY et al. Children born after autotransplantation of cryopreserved ovarian tissue: a review of 13 live births. Ann Med, 2011;43(6):437450. DOI:10.3109/07853890.2010.546807Google Scholar
Van Eyck, AS, Jordan, BF, Gallez, B et al. Electron paramagnetic resonance as a tool to evaluate human ovarian tissue reoxygenation after xenografting. Fertil Steril, 2009;92(1):374381. DOI:10.1016/j.fertnstert.2008.05.012Google Scholar
Donnez, J, Squifflet, J, Pirard, C, Jadoul, P, Dolmans, M-M. Restoration of ovarian function after allografting of ovarian cortex between genetically non-identical sisters. Hum Reprod, 2010;25(10):24892495. DOI:10.1093/humrep/deq186Google Scholar
Donnez, J, Squifflet, J, Pirard, C et al. Live birth after allografting of ovarian cortex between genetically non-identical sisters. Hum Reprod, 2011;26(6):13841388. DOI:10.1093/humrep/der089Google Scholar
Donnez, J, Dolmans, MM, Pirard, C et al. Allograft of ovarian cortex between two genetically non-identical sisters: case report. Hum Reprod, 2007;22(10):26532659. DOI:10.1093/humrep/dem211Google Scholar
Starzl, TE. Chimerism and tolerance in transplantation. Proc Natl Acad Sci U S A, 2004;101(Suppl 2):1460714614. DOI:10.1073/pnas.0404829101Google Scholar
Gineikiene, E, Stoskus, M, Griskevicius, L. Recent advances in quantitative chimerism analysis. Expert Rev Mol Diagn, 2009;9(8):817832. DOI:10.1586/erm.09.66Google Scholar
Donnez, J, Dolmans, MM, Demylle, D et al. Restoration of ovarian function after orthotopic (intraovarian and periovarian) transplantation of cryopreserved ovarian tissue in a woman treated by bone marrow transplantation for sickle cell anaemia: case report. Hum Reprod, 2005;21(1):183188. DOI:10.1093/humrep/dei268Google Scholar
Donnez, J, Martinez-Madrid, B, Jadoul, P et al. Ovarian tissue cryopreservation and transplantation: a review. Hum Reprod Update, 2006;12(5):519535. DOI:10.1093/humupd/dml032Google Scholar
Silber, SJ, Grudzinskas, G, Gosden, RG. Successful pregnancy after microsurgical transplantation of an intact ovary. 2008(1533–4406 (Electronic)).Google Scholar
Hamawi, K, Magalhaes‐Silverman, MD, Bertolatus, JA. Outcomes of renal transplantation following bone marrow transplantation. Am J Transplant, 2003;3(3):301305. DOI:10.1034/j.1600-6143.2003.00015.xGoogle Scholar
Donnez, J, Dolmans, M-M. Fertility preservation in women. N Engl J Med, 2017;377(17):16571665. DOI:10.1056/NEJMra1614676Google Scholar
Gellert, SE, Pors, SE, Kristensen, SG et al. Transplantation of frozen-thawed ovarian tissue: an update on worldwide activity published in peer-reviewed papers and on the Danish cohort. J Assist Reprod and Genet, 2018(1573–7330 (Electronic)). DOI:10.1007/s10815-018-1144-2Google Scholar
Diaz-Garcia, C, Domingo, J, Garcia-Velasco, JA et al. Oocyte vitrification versus ovarian cortex transplantation in fertility preservation for adult women undergoing gonadotoxic treatments: a prospective cohort study. Fertil Steril, 2018. DOI:10.1016/j.fertnstert.2017.11.018Google Scholar
Jensen, AK, Macklon, KT, Fedder, J et al. 86 successful births and 9 ongoing pregnancies worldwide in women transplanted with frozen-thawed ovarian tissue: focus on birth and perinatal outcome in 40 of these children. J Assist Reprod Genet, 2016. DOI:10.1007/s10815-016-0843-9Google Scholar
Donnez, J, Dolmans, MM, Demylle, D et al. Livebirth after orthotopic transplantation of cryopreserved ovarian tissue. Lancet, 2004;364(9443):14051410. DOI:10.1016/S0140-6736(04)17222-XGoogle Scholar

References

Sofiyeva, N, Siepmann, T, Barlinn, K, Seli, E, Ata, B. Gonadotropin-releasing hormone analogs for gonadal protection during gonadotoxic chemotherapy: a systematic review and meta-analysis. Reprod Sci, 2018 October 1. DOI:10.1177/1933719118799203Google Scholar
Ge, W, Chen, C, De Felici, M, Shen, W. In vitro differentiation of germ cells from stem cells: a comparison between primordial germ cells and in vitro derived primordial germ cell-like cells. Death Dis, 2015 October; 15(6):e1906. DOI:10.1038/cddis.2015.265Google Scholar
Lee, SJ, Schover, LR, Partridge, AH et al. American Society of Clinical Oncology recommendations on fertility preservation in cancer patients. J Clin Oncol, 2006;24(18):29172931.Google Scholar
Barton, SE, Najita, JS, Ginsburg, ES et al. Infertility, infertility treatment, and achievement of pregnancy in female survivors of childhood cancer: a report from the Childhood Cancer Survivor Study cohort. Lancet Oncol, 2013 August;14(9):873881. DOI:10.1016/S1470-2045(13)70251-1Google Scholar
Hirshfield, AN. Development of follicles in the mammalian ovary. Int Rev Cytol, 1991;12: 43101.Google Scholar
Broekmans, FJ, Soules, MR, Fauser, BC.Ovarian aging: mechanisms and clinical consequences. Endocr Rev, 2009;30(5):465493.Google Scholar
Faddy, MJ. Follicle dynamics during ovarian aging. Mol Cell Endocrinol, 2000;163(1–2):4348.Google Scholar
Faddy, MJ, Gosden, RG, Edwards, RG. Ovarian follicle dynamics in mice: a comparative study of three inbred strains and an F1 hybrid. J Endocrinol, 1983;96(1):2333.Google Scholar
Hansen, KR, Knowlton, NS, Thyer, AC et al. A new model of reproductive aging: the decline in ovarian non-growing follicle number from birth to menopause. Hum Reprod, 2008;23(3):699708.Google Scholar
Johnston, RJ, Wallace, WH. Normal ovarian function and assessment of ovarian reserve in the survivor of childhood cancer. Pediatr Blood Cancer, 2009;53(2):296302.Google Scholar
Steiner, AZ, Pritchard, D, Stanczyk, FZ et al. Association between biomarkers of ovarian reserve and infertility among older women of reproductive age. JAMA, 2017;318(14):13671376. DOI:10.1001/jama.2017.14588Google Scholar
McGee, EA, Hsueh, AJ. Initial and cyclic recruitment of ovarian follicles. Endocr Rev, 2000;21(2):200214.Google Scholar
Gallardo, TD, John, GB, Shirley, L. et al. Genomewide discovery and classification of candidate ovarian fertility genes in the mouse. Genetics, 2007;177:179194.Google Scholar
van Dooren, MF, Bertoli-Avellab, AM, Oldenburg, RA. Premature ovarian failure and gene polymorphisms. Curr Opin Obstet Gynecol, 2009;21(4):313317.Google Scholar
Toniolo, D, Rizzolio, F. X chromosome and ovarian failure. Semin Reprod Med, 2007;25(4):264267.Google Scholar
Zinn, AR, Ross, JL. Molecular analysis of genes on Xp controlling Turner syndrome and premature ovarian failure (POF). Semin Reprod Med, 2001;19:141146.Google Scholar
Qin, Y, Jiao, X, Simpson, JL, Chen Z-J. Genetics of primary ovarian insufficiency: new developments and opportunities. Hum Reprod Update, 2015:21(6):787808.Google Scholar
Di Pasquale, E, Beck-Peccoz P, Persani L. Hypergonadotropic ovarian failure associated with an inherited mutation of human bone morphogenetic protein-15 (BMP 15) gene. Am J Hum Genet, 2004;75(1):106111.Google Scholar
Gleicher, N, Weghofer, A, Barad, DH. A pilot study of premature ovarian senescence: I. Correlation of triple CGG repeats on the FMR1 gene to ovarian reserve parameters FSH and anti-Mullerian hormone. Fertil Steril, 2009;91(5):17001706.Google Scholar
Edson, MA, Nagaraja, AK, Matzuk, MM. The mammalian ovary from genesis to revelation. Endocr Rev, 2009;30:624712.Google Scholar
Qin, Y, Choi, Y, Zhao, H et al. NOBOX homeobox mutation causes premature ovarian failure. Am J Hum Genet, 2007;81(3):576581.Google Scholar
Chand, AL, Ooi, GT, Harrison, CA et al. Functional analysis of the human inhibin a subunit variant A257 T and its potential role in premature ovarian failure. Hum Reprod, 2007;22(12):32413248.Google Scholar
Sundblad, V, Chiauzzi, VA, Andreone, L et al. Controversial role of inhibin alpha-subunit gene in the etiology of premature ovarian failure. Hum Reprod, 2006;21(5):11541160.Google Scholar
Pagnamenta, AT, Taanman, JW, Wilson, CJ et al. Dominant inheritance of premature ovarian failure associated with mutant mitochondrial DNA polymerase gamma. Hum Reprod, 2006;21(10):24672473.Google Scholar
Oldenburg, RA, van Dooren, MF, de Graaf, B et al. A genome-wide linkage scan in a Dutch family identifies a premature ovarian failure susceptibility locus. Hum Reprod, 2008;23(12):28352841.Google Scholar
Aboura, A, Dupas, C, Tachdjian, G et al. Array comparative genomic hybridization profiling analysis reveals deoxyribonucleic acid copy number variations associated with premature ovarian failure. J Clin Endocrinol Metab, 2009;94(11):45404546.Google Scholar
Kok, HS, van Asselt, KM, Van Der Schouw, YT, Peeters, PHM, Wijmenga, C. Genetic studies to identify genes underlying menopausal age. Hum Reprod Update, 2005;11(5):483493.Google Scholar
Long, JR, Shu, XO, Cai, Q et al. Polymorphisms of the CYP1B1 gene may be associated with the onset of natural menopause in Chinese women. Maturitas, 2006;55(3):238246.Google Scholar
Liu, P, Lu, Y, Recker, RR, Deng, HW, Dvornyk, V. Association analyses suggest multiple interaction effects of the methylenetetrahydrofolate reductase polymorphisms on timing of menarche and natural menopause in white women. Menopause, 2010;17(1):185190.Google Scholar
Nelson, LM. Primary ovarian insufficiency. N Engl J Med, 2009;360:606614.Google Scholar
Kang, H, Lee, SK, Kim, MH et al. Acyl-CoA synthetase long-chain family member 6 is associated with premature ovarian failure. Fertil Steril, 2009;91:13391343.Google Scholar
Kovanci, E, Rohozinski, J, Simpson, JL et al. Growth differentiating factor-9 mutations may be associated with premature ovarian failure. Fertil Steril, 2007;87:143146.Google Scholar
Rohr, J, Allen, EG, Charen, K et al. Anti-Mullerian hormone indicates early ovarian decline in fragile X mental retardation (FMR1) premutation carriers: a preliminary study. Hum Reprod, 2008;23(5):12201225.Google Scholar
Jiao, X, Qin, C, Li, J et al. Cytogenetic analysis of 531 Chinese women with premature ovarian failure. Hum Reprod, 2012;27(7):22012207.Google Scholar
Pastore, L, Johnson, J. The FMR1 gene, infertility, and reproductive decision-making: a review. Front Genet, 2014;5:195.Google Scholar
Phillips, KA, Collins, IM, Milne, RL et al. Anti-Müllerian hormone serum concentrations of women with germline BRCA1 or BRCA2 mutations. Hum Reprod, 2011;31(5):11261132.Google Scholar
Giordano, S, Garrett-Mayer, E, Mittal, N et al. Association of BRCA1 mutations with impaired ovarian reserve: connection between infertility and breast/ovarian cancer risk. J Adolesc Young Adult Oncol, 2016;5(4):337343.Google Scholar
Johnson, L, Sammel, MD, Domchek, S et al. Antimüllerian hormone levels are lower in BRCA2 mutation carriers. Fertil Steril: May, 2017;107(5):12561265.Google Scholar
Lin, W, Titus, S, Moy, F, Ginsburg, ES, Oktay, K. Ovarian aging in women with BRCA germline mutations. J Clin Endocrinol Metab, 2017 October 1;102(10):38393847.Google Scholar
Oktay, K, Turan, V, Titus, S, Stobezki, R, Liu, L. BRCA mutations, DNA repair deficiency, and ovarian aging1. Biol Reprod, 2015 September;93(3):67. Published online 2015 July 29. DOI:10.1095/biolreprod.115.132290 PMCID: PMC4710189. PMID: 26224004.Google Scholar
Derks-Smeets, AP, van Tilborg, TC, van Montfoort, A et al. BRCA1 mutation carriers have a lower number of mature oocytes after ovarian stimulation for IVF/PGD. J Assist Reprod Genet, 2017 November;34(11):14751482.Google Scholar
de la Noval, BD. Potential implications on female fertility and reproductive lifespan in BRCA germline mutation women. Arch Gynecol Obstet, 2016 November;294(5):10991103. Epub 2016 August 25.Google Scholar
Ruth, KS, Murray, A. Lessons from genome-wide association studies in reproductive medicine: menopause. Semin Reprod Med, 2016 July;34(4):215223. DOI:10.1055/s-0036-1585404Google Scholar
Tohlob, D, Abo Hashem, E, Ghareeb, N et al. Association of a promoter polymorphism in FSHR with ovarian reserve and response to ovarian stimulation in women undergoing assisted reproductive treatment. Reprod Biomed Online, 2016 September;33(3):391397.Google Scholar
La Marca, A, Papaleo, E, Alviggi, C et al. The combination of genetic variants of the FSHB and FSHR genes affects serum FSH in women of reproductive age. Hum Reprod, 2013 May;28(5):13691374. DOI:10.1093/humrep/det061 Epub 2013 March 15.Google Scholar
Wood, MA, Rajkovic, A. Genomic markers of ovarian reserve. Semin Reprod Med, 2013 November;31(6):399415. DOI:10.1055/s-0033-1356476Google Scholar
Riccetti, L, De Pascali, F, Gilioli, L et al. Genetics of gonadotropins and their receptors as markers of ovarian reserve and response in controlled ovarian stimulation. Best Pract Res Clin Obstet Gynaecol, 2017 October;44:1525. DOI:10.1016/j.bpobgyn.2017.04.002 Epub 2017 April 17.CrossRefGoogle ScholarPubMed
Chen, CT, Liu, CT, Chen, GK et al. Meta-analysis of loci associated with age at natural menopause in African-American women. Hum Mol Genet, 2014 June 15;23(12):33273342. DOI:10.1093/hmg/ddu041 Epub 2014 February 2.Google Scholar
Rahmani, M, Earp, MA, Ramezani Tehrani, F et al. Shared genetic factors for age at natural menopause in Iranian and European women. Hum Reprod, 2013 July;28(7):19871994. DOI:10.1093/humrep/det106 Epub 2013 April 16.Google Scholar
Shi, J, Zhang, B, Choi, JY et al. Age at menarche and age at natural menopause in East Asian women: a genome-wide association study. Age, 2016 December;38(5–6):513523. DOI:10.1007/s11357-016-9939-5 Epub 2016 September 14.Google Scholar
Schuh-Huerta, SM, Johnson, NA, Rosen, MP et al. Genetic variants and environmental factors associated with hormonal markers of ovarian reserve in Caucasian and African American women. Hum Reprod, 2012 February;27(2):594608. DOI:10.1093/humrep/der391 Epub 2011 November 24.Google Scholar
Pyun, JA, Kim, S, Cho, NH et al. Genome-wide association studies and epistasis analyses of candidate genes related to age at menarche and age at natural menopause in a Korean population. Menopause, 2014 May;21(5):522529. DOI:10.1097/GME.0b013e3182a433f7Google Scholar
Tal, R, Seifer, DB. Ovarian reserve testing: a user’s guide. Am J Obstet Gynecol, 2017 August;217(2):129140. DOI:10.1016/j.ajog.2017.02.027 Epub 2017 February 21.Google Scholar
Souter, I, Smith, KW, Dimitriadis, I et al. The association of bisphenol-A urinary concentrations with antral follicle counts and other measures of ovarian reserve in women undergoing infertility treatments. Reprod Toxicol, 2013 December;42:224231. DOI:10.1016/j.reprotox.2013.09.008 Epub 2013 October 4.Google Scholar
Karwacka, A, Zamkowska, D, Radwan, M, Jurewicz, J. Exposure to modern, widespread environmental endocrine disrupting chemicals and their effect on the reproductive potential of women: an overview of current epidemiological evidence. Hum Fertil (Camb), 2017 July;31:124. DOI:10.1080/14647273.2017.1358828 [Epub ahead of print]Google Scholar
Vabre, P, Gatimel, N, Moreau, J et al. Environmental pollutants, a possible etiology for premature ovarian insufficiency: a narrative review of animal and human data. Environ Health, 2017 April 7;16(1):37. DOI:10.1186/s12940-017-0242-4Google Scholar
Mínguez-Alarcón, L, Gaskins, AJ. Female exposure to endocrine disrupting chemicals and fecundity: a review. Curr Opin Obstet Gynecol, 2017 August;29(4):202211. DOI:10.1097/GCO.0000000000000373Google Scholar
Butts, S, Sammel, M, Greer, C et al. Cigarettes, genetic background, and menopausal timing: the presence of single nucleotide polymorphisms in cytochrome P450 genes is associated with increased risk of natural menopause in European-American smokers. Menopause, 2014 July;21(7):694701.Google Scholar
Bhattacharya, P, Keating, AF. Impact of environmental exposures on ovarian function and role of xenobiotic metabolism during ovotoxicity. Toxicol Appl Pharmacol, 2012 June 15;261(3):227235. DOI:10.1016/j.taap.2012.04.009 Epub 2012 April 13.Google Scholar
Blum, MGB, Heyer, E, Francois, O, Austerlitz, F. Matrilineal fertility inheritance detected in hunter-gatherer populations using the imbalance of gene genealogies. PLoS Genet, 2006;2(8):e122.Google Scholar
Wood, JW. Fecundity and natural fertility in humans. Oxf Rev Reprod Biol, 1989;11:61109.Google Scholar
Frank, O, Bianchi, PG, Campana, A. The end of fertility: age, fecundity and fecundability in women. J Biosoc Sci, 1994;26(3):349368.Google Scholar

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