Published online by Cambridge University Press: 23 October 2024
Lung cancer has emerged as a distinct disease in women, and women have unique risk factors as compared to men. Women are more likely to be diagnosed at a young age with adenocarcinoma, lack a significant smoking history and carry driver mutations. Current screening guidelines center around tobacco use, so health care disparities related to gender may impact those women who never smoked and/or prone to lung cancer from distinct etiologies. Molecular and immune markers are important in the workup for cancer, and new treatments with targeted and immune-mediated therapies are available. Women diagnosed with lung cancer have improved survival rates compared to men even while accounting for stage of diagnosis, age, smoking history and treatment modality. Lung cancer survivorship issues can contribute to significant symptom burden, and these can include cancer-related fatigue, reproductive issues, sexual health and sleep disruption. The impact of lung cancer and its’ therapies can affect quality of life especially when treatment-related complications are persistent.
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