Book contents
- Cambridge Handbook of Pain Medicine
- Cambridge Handbook of Pain Medicine
- Copyright page
- Contents
- Contributors
- Pain Handbook Introduction
- Part I Introduction to Pain: Pain Signaling Pathways
- Part II Common Categories of Pharmacologic Medications to Treat Chronic Pain
- Part III Chronic Pain Conditions Head and Neck
- Part IV Spine
- Part V Extremities
- Part VI Misc
- Chapter 26 Post-herpetic Neuralgia (PHN)
- Chapter 27 Complex Regional Pain Syndrome (CRPS)
- Chapter 28 Sickle Cell Disease
- Chapter 29 Breast Pain
- Chapter 30 Post-thoracotomy Pain
- Chapter 31 Multiple Sclerosis Pain
- Chapter 32 Cerebral Palsy
- Chapter 33 Myofascial Pain Syndrome
- Chapter 34 Post-stroke Pain
- Chapter 35 Chronic Abdominal Pain
- Chapter 36 Chronic Pelvic Pain
- Chapter 37 Postsurgical Nerve Entrapment
- Chapter 38 Cancer Pain
- Part VII Adjunctive Therapy
- Index
- References
Chapter 28 - Sickle Cell Disease
from Part VI - Misc
Published online by Cambridge University Press: 01 December 2023
Book contents
- Cambridge Handbook of Pain Medicine
- Cambridge Handbook of Pain Medicine
- Copyright page
- Contents
- Contributors
- Pain Handbook Introduction
- Part I Introduction to Pain: Pain Signaling Pathways
- Part II Common Categories of Pharmacologic Medications to Treat Chronic Pain
- Part III Chronic Pain Conditions Head and Neck
- Part IV Spine
- Part V Extremities
- Part VI Misc
- Chapter 26 Post-herpetic Neuralgia (PHN)
- Chapter 27 Complex Regional Pain Syndrome (CRPS)
- Chapter 28 Sickle Cell Disease
- Chapter 29 Breast Pain
- Chapter 30 Post-thoracotomy Pain
- Chapter 31 Multiple Sclerosis Pain
- Chapter 32 Cerebral Palsy
- Chapter 33 Myofascial Pain Syndrome
- Chapter 34 Post-stroke Pain
- Chapter 35 Chronic Abdominal Pain
- Chapter 36 Chronic Pelvic Pain
- Chapter 37 Postsurgical Nerve Entrapment
- Chapter 38 Cancer Pain
- Part VII Adjunctive Therapy
- Index
- References
Summary
Sickle cell crisis is a term used to capture myriad acute manifestations of sickle cell disease (SCD). Underlying pathophysiology is due to polymerization of HbS, sickling of erythrocytes, and microvascular occlusion and injury. Sickle cell disease and related pain is common in the US, especially among black Americans. Routine newborn screening picks up the majority of cases and helps guide prevention and treatment of acute pain crises early on. The mainstay of treating vaso-occlusive crises is analgesia and is often achieved with NSAIDs, opioids, or combination therapy.
- Type
- Chapter
- Information
- Cambridge Handbook of Pain Medicine , pp. 228 - 233Publisher: Cambridge University PressPrint publication year: 2023
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