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from Section IV - Endometrial Cancer
Published online by Cambridge University Press: 20 July 2023
Secondary cytoreductive surgery (SCS) for endometrial cancer is an effective treatment modality for the treatment of recurrent endometrial cancer, even when it is non-exenterative. In appropriately selected patients SCS offers improved oncologic outcomes compared with radiation therapy, chemotherapy with or without radiation therapy, and hormonal therapy. Achieving complete or optimal cytoreduction is critical to maximizing the impact that SCS can offer. When selecting a patient for SCS, given the lack of prospectively validated selection criteria, discussion in a multidisciplinary form is recommended. An important next step is to investigate how SCS can work in conjunction with other modalities of therapy, including newly emerging evidence on immunotherapy.
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