It is evident to anyone who is at all familiar with the documents and witnesses of the times that Aztec society at the time of the discovery of Mexico appears to be intensely religious, that all public and private life was invaded, so to speak, by rites and dominated by beliefs. But what exactly was the place of religion and its ministrants in the hierarchy of powers? To what degree was the priestly function interwoven with that of government and the administration of the city? Can the regime of ancient Mexico be described as a theocracy? To answer these questions, it is of no small use, first, to go back to the period preceding the foundation of Mexico-Tenochtitlan.

The influence of man on man is exercised sometimes to assemble a group of individuals moved toward common action, sometimes to remedy the antagonisms which naturally result from the conflict of human wills. These two situations give rise to two forms of authority which are seldom found in the same person, since one form is essentially exciting and the other essentially calming. The contrast between them can be illustrated by the two images of the bridge of Arcole and the oak of Vincennes.

The print which shows Bonaparte hurling himself at the enemy and urging his soldiers to follow sums up in a single scene all the influence toward action he had exercised on them since he had taken command. He had found troops low in morale and without any disposition to take the offensive; he breathed his own fire into them; his famous proclamation tended to imbue them with his own ambition, and united them as participants in his plan. By a remarkable feat of transference, impatient because he was without glory, he made them realize that they were without shoes, and he materialized for them his own vast dreams in the visible form of “the fertile plains of Lombardy.”

Serious intellectuals in Japan have been concerned with problems of tradition and modernization not only in the postwar period but at least as far back as the Meiji Restoration, although it is true that in each period the problems were viewed in different ways. The issue of tradition and modernization is not peculiar to Japan. However, there are sufficient reasons for the fact that this issue has been and is being conspicuously argued among the Japanese.

Acculturation, or more precisely Westernization, in the Near and Middle East has gone through distinct typical phases. After the shock of inferiority discovered, an almost complete surrender to the foreign values and (not infrequently misunderstood) aspirations; then, with Westernization partially realised, a recoiling from the alien, which however continues to be absorbed greedily, and a falling back on the native tradition; this tradition is restyled and, in some cases, newly created with borrowed techniques of scholarship to give respectability to the results. Finally, with Westernization very largely completed in terms of governmental reforms, acceptance of the values of science and adoption of Western literary and artistic form, regained self-confidence expresses itself in hostility to the West and insistence on the native and original character of the borrowed product.

The adoption of plant-based meat analogues is increasing as an alternative to real meat products among consumers because they offer a more ecologically friendly and sustainable source of protein while also alleviating the ethical concerns related to livestock rearing and slaughter (1). However, there are concerns regarding plant-based meat analogues in terms of its nutritional quality, particularly their protein digestibility. This study aims to compared between chicken and plant-based chicken analogues in terms of nutritional composition and degree of protein hydrolysis.

Proximate analyses were performed for raw and cooked samples to assess protein, fat, and energy concentrations in two chicken samples (breast and thigh) and four commercial plant-based chicken (P-C1[Wheat Protein 37%, Pea Protein 10%], P-C2 [ Soya Protein 63%], P-C3 [ Soya and Wheat Protein 83%], and P-C4 [Soya Protein 30%, Pea Protein 2%]). As a first step, the proximate analyses were assessed for the averaged samples, then the product-cooking interactions was assessed using a one-way ANOVA followed by Tukey test (p <0.05). In vitro digestion was performed following the INFOGEST harmonised static in vitro digestion model (2) for cooked samples. After digestion, o- Phthaldialdehyde (OPA) assay was carried out to measure the degree of protein hydrolysis for each sample, and two-way ANOVA test was performed.

Protein content of chicken was higher compared with the plant-based chicken, whereas fat content and energy concentrations were higher in plant-based chicken. The protein content of chicken was higher for raw and cooked samples (raw: 19.8 ± 0.38 g/100 g; cooked: 30.55 ± 4 g/100g), compared with plant-based chicken (raw: 13.8 ± 5.3 g/100 g; cooked: 23.4 ± 4.5 g/100g). Plant-based chicken have a higher fat content and energy concentrations for raw and cooked samples (raw:6.52 ± 1.5 g/100 g; cooked: 9.6 ± 3.17 g/100g) and (raw:189.4 ± 28.1 g/100 g; cooked: 291.3 ± 48.1 g/100g) respectively; compared to chicken fat content (raw:4.6 ± 2.7 g/100 g; cooked: 6.1 ± 4 g/100g) and energy concentration (raw:150.9 ± 25.4 g/100 g; cooked: 228.3 ± 20.7 g/100g). The product-cooking interactions showed a significant increase (P ≤0.0001) in the protein content (raw: 15.6 ± 2.3g/100g to 19.8 ± 0.74 g/100g; cooked: 21.4 ± 0.55 g/100g to 33.06 ± 0.71 g/100g), and fat content P<0.001 (raw: 2.7 ± 0.06 g/100g to 8.3 ± 0.27 g/100g; cooked: 3.29 ± 0.19 g/100g to 13.22 ± 0.33 g/100g) in both chicken and plant-based chicken samples. No significant product-cooking interactions on energy content was found. The results from a two-way ANOVA test of the OPA and the degree of hydrolysis analyses demonstrated a significant increase in the degree of hydrolysis of chicken samples compared with plant-based chicken (P<0.0001).

The degree of hydrolysis and digestibility of chicken and chicken analogues was influenced by protein type, nutrient composition, and processing. These findings would provide substantial information for the improvement of plant-based chicken products with enhanced nutritional profiles. This work will be extended to investigate the availability and digestibility of individual amino acids.

Definitions are often viewed with a skeptical eye. The most diverse definitions are successfully applied to a given subject; their discrepancies are noted, and conclusions are drawn concerning the vanity of quibbling over words. In the best of cases the writer, before beginning his own exposition, proposes the definition which he will follow exclusively, convinced that all terminologies are valid so long as they are explicit and respected.

Vitamin D status has been found to be inversely associated with risk of respiratory tract infections (RTIs)(1). It varies by ethnicity, with several ethnic minority groups in the United Kingdom (UK) reported to be at a higher risk of vitamin D deficiency (serum 25-hydroxyvitamin D (25(OH)D) concentrations <25 nmol/L) compared to their white counterparts(2, 3). However, the relationship between serum 25(OH)D concentrations and incidence of RTIs by ethnicity in the UK remains unclear. This study aimed to investigate the association between serum 25(OH)D concentrations and likelihood of hospitalisation for RTI in UK ethnic groups.

A nested, case-control study was conducted using data from UK Biobank, which has data for 500k adults for serum 25(OH)D and hospital episodes from linked records. Binary logistic regression models were used to explore the association between serum 25(OH)D concentrations and likelihood of RTIs overall, and by ethnicity.

Of the 36,772 participants included in the analysis, 12,638 (34%) were white Caucasian, 10,311 (28%) Asian, 7,138 (19%) black, 4,034 (11%) other, and 2,651 (7%) of mixed ethnicity. In fully adjusted models, compared to participants with a serum 25(OH)D concentration <15 nmol/L (severe deficiency), those with 25-49 nmol/L, 50-74 nmol/L, and ≥75 nmol/L were found to have statistically significantly lower odds of RTI hospitalisation, with odds ratios (ORs) of 0.53 (95% CI: 0.37, 0.75), 0.61 (95% CI: 0.40, 0.92) and 0.54 (95% CI: 0.30, 0.97), respectively. In the subgroup analysis, ethnic minorities and white individuals with vitamin D deficiency (<25 nmol/L) were more likely to be hospitalised with RTI compared to those that were not deficient, with ORs of 1.36 (95% CI: 1.02, 1.81) and 2.03 (95% CI: 1.30, 3.17), respectively. This association was not statistically significant within ethnic minority subgroups when analysed separately.

Serum 25(OH)D concentrations above 25 nmol/L are associated with lower likelihood of RTI hospitalisation among UK adults. This finding was noted across white and ethnic minority groups, although ethnic minorities with vitamin D deficiency had a lower likelihood of RTIs compared to white individuals. Further studies are warranted to validate these findings and explore the mechanisms underlying the association between vitamin D status and RTIs in different ethnic groups.

Acknowledgements

This project was conducted using the UK Biobank resource under project 15168.

In Iroquois and Algonquin legend there is the story of a girl who submits in the dark of night to a man she believes to be her brother. Every detail seems to identify him: physical appearance, clothing, a scratched cheek attesting to the heroine's virtue. When formally accused by her, the brother reveals that he has a second self (Sosie) or, more precisely, a double; the bond between them is so strong that everything befalling the one is automatically transmitted to the other : the torn garment, the wounded face. In order to convince his incredulous sister, the young man kills his double before her eyes, but with this single blow he pronounces his own death sentence, since their destinies are one.

There are certain terms which, for reasons no longer discoverable, have taken on an emotional force which impels people either to admire what they seem to stand for or to dislike it. Among such terms are the temporal and the eternal, the dynamic and the static, the unified and the multiple, the universal and the local. At the present time to say that a work of art, for instance, has been “universally admired” is presumably also to say that it is better than one which is admired only in France or Italy or the United States. To say that courage or truthfulness or charity have always been “highly esteemed” is also to say that they are inherently nobler qualities than, for example, originality or wit, which are highly esteemed only in certain epochs. It is this curious aura of emotivity which Professor A. O. Lovejoy in one of his ingenious terminological inventions once called “metaphysical pathos.” “Metaphysical pathos” is not merely the name for the power which terms have of stimulating pleasant emotions, of making men feel that the things they name are good. It may also be of an unpleasant sort. It may induce dislike as well as admiration. Where one man speaks of the dynamic with something approaching awe, another calls it “aimless striving” or “spiritual restlessness,” forgetting that only a hundred and fifty years ago the German Romantic philosophers could think of no nobler end of man than striving for striving's sake. Hence it is always useful and for the most part necessary to look closely at those abstractions by means of which we justify our programs. It is for this reason that it may be well to examine one of our own sacred words, “tradition,” which seems to have replaced even that perennial favorite of the poets, “nature.”

The theoretic structure of Marxian economy was elaborated to provide an understanding of the laws of the motion of capitalism. The motion of capitalism, however, is nothing but the process of economic development under conditions of multiple centers of investment-decisions. It becomes, then, an interesting question to ask how much of the theoretic structure of Marx applies to the problems of economic development in general and how much is limited to those aspects alone which follow from the theoretically contingent condition of decentralized investment-decisions. It will not, therefore, be the primary purpose of this paper to examine the adequacy of the conceptual structure of Marxian economic thought, or even its relative advantages or disadvantages over the more widely accepted school, following the inquiries of Walras, Menger, Jevons, and others; but, rather, to assume the general framework of Marxian theory and attempt to seek an answer within its limits.

Writing history, in the humblest sense of the word, is above all a process of dating events, inscribing them in a chronology. Yet this framework, empty and elementary though it may appear, possesses nonetheless properties of its own, somewhat as real extension, the domain of orientation and weight, differs from pure geometrical space. Concrete time, too, has certain qualities, qualities which are not necessarily everywhere the same, and which take their configuration from the conception of the world particular to each civilization. These local cosmologies remain implicit for the most part, even though they frequently give rise to doctrines which can be highly complex. Philosophers and theologians have framed such constructions, basing them to a certain extent on the body of astronomical knowledge which they found at their disposal. But these scholarly interpretations do not limit themselves to a mere translation of the factual data that an observation of the stars could provide. The astronomical data serve as simple points of orientation for the elaboration of vast graphs, on whose empty expanses the vicissitudes of history would trace their paths. These constructions are like niches erected in advance, awaiting the events to come, an immutable order of vintages to which the individual is so thoroughly accustomed that he finds it impossible even to conceive of a different disposition.

Cybernetics has fallen prey to snobs and journalists, who, in dealing with it, tend to mix myth with science. In this study we shall try to sift out the chaff, which a regrettable sensationalism has needlessly mixed with the good grain. Concentrating our attention on the rational bases and some of the lines of force of this new field of study, we shall try to eliminate the element of fable, but we shall not prohibit ourselves from opening windows on any perspectives that seem reasonable.

The notion of “information,” cornerstone of cybernetics, sheds light on the theory of knowledge. What is science, indeed, but an interpretation, which tries to be objective, of the flood of signals with which the universe submerges us? A Protean notion, it permits us to discover a certain unity among the most disparate phenomena. But it is a dangerous notion, too, because of the multiplicity of senses one may give to it.

The truly great social drama of mankind has not been the oppression of the minorities by the majorities. This form of tyranny affects by definition only small groups of human beings, and if it has often assumed violent forms, it has nevertheless retained over the centuries its episodic character—excepting the case of the Jewish people.

There are known differences in biological functionality between vitamin D2 and D3. It is suspected from randomised control trial (RCT) data that vitamin D2 supplementation causes a reduction in serum 25-hydroxyvitamin D3 (25(OH)D3) concentrations (1), but the size of the effect has yet to be fully assessed across multiple studies. The aim of this study was to undertake a systematic review and meta-analysis of the effect of vitamin D2 supplementation on serum 25(OH)D3 concentrations.

PUBMED was searched for publications from 1st January 1975 to 1st February 2023. Of the 182 papers retrieved, 29 were included in the systematic review, and of those, 18 were suitable for meta-analysis.

The meta-analysis found significant reductions in serum D3 after vitamin D2 supplementation compared with control, for both end of trial between groups data (weighted mean difference (WMD) (random) = −13.51 nmol/L; 95% CI: −20.14, −6.89; P < 0.0001) and absolute change over the trial (WMD (random) = −9.25 nmol/L; 95% CI: −14.40, −4.10; P = 0.0004). Similar results were found when D2 supplementation was compared to D3 supplementation, although as expected, the magnitude of the difference was larger, with WMD (random) = −46.20 nmol/L (95% CI: −60.80, −31.60; P < 0.00001) for end of trial data, and WMD (random) = −56.23 nmol/L (95% CI: -69.17, −43.28; P < 0.00001) for absolute change.

Overall, we found that vitamin D2 supplementation produces significant reductions in serum 25(OH)D3 concentrations, when compared to either control or vitamin D3 supplementation. An inverse relationship between vitamin D2 and D3 concentrations has been proposed in the literature (2). A regulatory mechanism that disposes of 25(OH)D after an increase in vitamin D concentrations could explain our results (3). Moreover, supplementation with vitamins D2 and D3 has differential effects on gene expression (4). However, longer-term research is needed to establish whether clinical advice should recommend vitamin D3 supplements over vitamin D2 supplements, where appropriate.