To evaluate the clinical efficacy of tobramycin dexamethasone eye ointment combined with a catheter in endoscopic dacryocystorhinostomy.

Eighty chronic dacryocystitis patients were randomly divided into two groups: observation (n = 39) and control (n = 41). Both groups underwent endoscopic dacryocystorhinostomy. The observation group used tobramycin dexamethasone eye ointment and catheter support, while the control group used only the eye ointment.

No statistical differences were found in gender, age, disease course or eye type. However, the anastomotic formation time and bleeding amount were significantly different between the two groups (p < 0.001). After six months of follow up, there were no significant complications differences (p > 0.05). The fluorescein disappearance test time in the observation group was significantly shorter (p < 0.001), and the clinical effective rate was significantly higher (97.4 per cent vs 78 per cent, p < 0.05) in the observation group.

Using tobramycin dexamethasone eye ointment combined with a catheter slightly prolongs the operation time and increases bleeding, but promotes anastomotic healing, accelerates tear drainage, improves the operation success rate and is economically efficient.