Field research from 1986 to 1988 evaluated control of alfalfa, dandelion, orchardgrass, and annual weeds in corn with sequential herbicide treatments. Glyphosate applied the previous fall controlled 95% or more of the dandelion and orchardgrass before postemergence treatments. Atrazine applied early preplant or with paraquat the day before planting only partially controlled the perennial species. Atrazine applied postemergence usually controlled vegetation escaping initial treatment except orchardgrass following the atrazine treatments. Adding tridiphane increased weed control with atrazine or cyanazine applied postemergence only when fall panicum was present. Herbicides applied postemergence increased corn yield compared to the initial treatments alone, and few differences among postemergence treatments were observed. Sequential treatments which included glyphosate applied in the fall controlled 82% or more of each perennial species before the next growing season. Orchardgrass control was 81% or less the following spring when the initial treatment was atrazine or atrazine plus paraquat.