Using diverse real-world examples, this text examines what models used for data analysis mean in a specific research context. What assumptions underlie analyses, and how can you check them? Building on the successful 'Data Analysis and Graphics Using R,' 3rd edition (Cambridge, 2010), it expands upon topics including cluster analysis, exponential time series, matching, seasonality, and resampling approaches. An extended look at p-values leads to an exploration of replicability issues and of contexts where numerous p-values exist, including gene expression.Developing practical intuition, this book assists scientists in the analysis of their own data, and familiarizes students in statistical theory with practical data analysis. The worked examples and accompanying commentary teach readers to recognize when a method works and, more importantly, when it doesn't. Each chapter contains copious exercises. Selected solutions, notes, slides, and R code are available online, with extensive references pointing to detailed guides to R.

Most textbooks on regression focus on theory and the simplest of examples. Real statistical problems, however, are complex and subtle. This is not a book about the theory of regression. It is about using regression to solve real problems of comparison, estimation, prediction, and causal inference. Unlike other books, it focuses on practical issues such as sample size and missing data and a wide range of goals and techniques. It jumps right in to methods and computer code you can use immediately. Real examples, real stories from the authors' experience demonstrate what regression can do and its limitations, with practical advice for understanding assumptions and implementing methods for experiments and observational studies. They make a smooth transition to logistic regression and GLM. The emphasis is on computation in R and Stan rather than derivations, with code available online. Graphics and presentation aid understanding of the models and model fitting.