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Deep brain stimulation (DBS) is one of the most effective tools in the treatment of Parkinson’s disease. Being a last-resort therapy for many years, it recently advanced to a valuable option in moderate and even earlier stages. Different nuclei of the basal ganglia have been successfully targeted with various effects, risks and stimulation-induced side effects. Advances in implantation technique and accuracy, neuroimaging and implant technology helped make DBS a mostly safe and successful procedure, although the full potential of recent technical advantages such as directional stimulation, brain sensing or remote programming have yet to be fully explored.
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