This chapter provides a comprehensive discussion of the concept and practice of multiple stressor debriefing (MSD). MSD addresses the thoughts and feelings about the stressors that personnel encounter while participating in a disaster operation. The model of debriefing is applicable to many other trauma-response groups such as medical, police and fire personnel, Federal Emergency Management Agency (FEMA) workers, as well as direct victims. The primary advantage of an individual debriefing is that it provides an opportunity to aid persons who might not otherwise receive an appropriate level of individual attention. An advantage of a family debriefing is that families can be quickly and effectively mobilized to provide support for the affected person. Evaluating the effectiveness of debriefings through anonymous questionnaires or by asking participants for their feedback at the conclusion of the debriefing is an important step in creating a useful intervention.