Introduction. Traditionally the control of fruit flies is based on the use
of pesticides, which increase production costs and have led to many environmental
concerns. Our study aimed to evaluate the effect of neem cake on the larval and pupal
stages of Ceratitis capitata. Materials and methods. Third
instar larvae were transferred to plastic vials with neem cake in different proportions.
The treatments consisted of vermiculite with neem cake in the concentrations: control
(vermiculite only), then (10, 25, 50, 75 and 100)% of neem seed cake. The bioassay was
completely randomized, with six treatments, ten replicates and ten third instar larvae per
replicate. The results were statistically analyzed. Results. At
concentrations of 75% or more of neem cake in vermiculite, practically no adult flies
emerged. At 50%, more than 80% of the adults did not emerge and the pupal period was
prolonged. The sex ratio of the adults was not affected after the contact of the pupae
with the neem cake. The estimated lethal concentrations to kill 50% and 90% of the
population were 30.6% and 51.6%, respectively. Conclusion. The neem seed cake
has contact actions against the larval-pupal stage of C.
capitata. Neem seed cake in the pupation substrate can cause high
mortality when its concentration is 50% or more, and it prolongs the delay of the pupal
period of C. capitata.