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1 results

  • Plasmablastic lymphoma of the larynx: report of two cases

  • K Stephenson, S Peer, D Govender, J J Fagan
  • Journal:
    The Journal of Laryngology & Otology / Volume 127 / Issue 1 / January 2013
    Published online by Cambridge University Press:
    19 September 2012, pp. 96-99
    Print publication:
    January 2013
  • Objective:

    To report two cases of laryngeal plasmablastic lymphoma, a rare and relatively recently described form of non-Hodgkin's lymphoma. It has not previously been described in the larynx, nor associated with upper airway obstruction.

    Case reports:

    We describe the clinicopathological features of two such cases in human immunodeficiency virus positive patients, and we discuss their unusual presentations and diagnostic features.

    Conclusion:

    When evaluating a laryngeal tumour, plasmablastic lymphoma and other non-Hodgkin's lymphomata should be considered as differential diagnoses, particularly in the setting of a high prevalence of human immunodeficiency virus infection. Biopsy with detailed histopathological and immunohistochemical evaluation is recommended to ensure correct diagnosis and optimal management.