Regional pine seedling tolerance experiments were conducted on five pine (Pinus spp.) species at ten forest nurseries in 1974. Similar studies in 1975 included four pine species at nine locations. From these studies, herbicides appearing safe for preemergence use are bifenox [methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate] at 1.7, 3.4, and 6.7 kg/ha; butralin [4-(1,1-dimethylethyl)-N-(1-methylpropyl)-2,6-dinitrobenzenamine] at 2.2, 3.4, 4.5, and 6.7 kg/ha, napropamide [2-(α-naphthoxy)-N,N-diethylpropionamide] at 1.7 kg/ha; napropamide at 1.1 kg/ha plus bifenox at 3.4 kg/ha; dinitramine (N4,N4-diethyl-α,α,α-trifluoro-3,5-dinitrotoluene-2,4-diamine) at 0.37 and 0.74 kg/ha; diphenamid (N,N-dimethyl-2,2-diphenylacetamide) at 4.5 kg/ha, trifluralin (α,α,α-trifluoro-2,6-dinitro-N,N-dipropyl-p-toluidine) at 1.1 kg/ha; and profluralin [N-(cyclopropylmethyl)-α,α,α-trifluoro-2,6-dinitro-N-propyl-p-toluidine] at 1.1 and 2.2 kg/ha. Southern pine seedling tolerance to oryzalin (3,5-dinitro-N4,N4-dipropylsulfanilamide) was unacceptable at 1.1 and 2.2 kg/ha. Napropamide severely stunted seedlings at 6.7 kg/ha but affected seedlings only slightly at 3.4 kg/ha.