We consider a stochastic model for the spread of an epidemic amongst a closed homogeneously mixing population, in which there are several different types of infective, each newly infected individual choosing its type at random from those available. The model is based on the carrier-borne model of Downton (1968), as extended by Picard and Lefèvre (1990). The asymptotic distributions of final size and area under the trajectory of infectives are derived as the initial population becomes large, using arguments based on those of Scalia-Tomba (1985), (1990). We then use our limiting results to compare the asymptotic final size distribution of our model with that of a related multi-group model, in which the type of each infective is assigned deterministically.

We consider a stochastic model for the spread of a carrier-borne epidemic amongst a closed homogeneously mixing population, in which a proportion 1 − π of infected susceptibles are directly removed and play no part in spreading the infection. The remaining proportion π become carriers, with an infectious period that follows an arbitrary but specified distribution. We give a construction of the epidemic process which directly exploits its probabilistic structure and use it to derive the exact joint distribution of the final size and severity of the carrier-borne epidemic, distinguishing between removed carriers and directly removed individuals. We express these results in terms of Gontcharoff polynomials. When the infectious period follows an exponential distribution, our model reduces to that of Downton (1968), for which we use our construction to derive an explicit expression for the time-dependent state probabilities.

We consider the spread of a general epidemic amongst a population consisting of invididuals with differing susceptibilities to the disease. Deterministic and stochastic versions of the basic model are described and analysed. For both versions of the model we show that assuming a uniform susceptible population, with average susceptibility, leads to an increased spread of infection. We also show how our results can be extended to the carrier-borne epidemic model of Weiss (1965).

We provide a formal proof of a conclusion due to Abakuks (1974) which states that the expected number of survivors in Downton's carrier-borne epidemic model approaches the limit (ρ /π)δ as the initial number of susceptibles tends to infinity. Here ρ denotes the relative removal rate for carriers, π denotes the conditional probability that an infected susceptible will become a carrier, δ denotes the Kronecker delta function and denotes the initial number of carriers.

This paper is concerned with the area under the trajectory of carriers in the Downton carrier-borne epidemic (1968). Its Laplace–Stieltjes transform is studied, and a recursive equation derived for it. Its mean is examined in some detail and the solution obtained is expressed as a power series in π, the proportion of the infected susceptibles becoming carriers.

This paper is concerned with the expected ultimate size of the Downton carrier-borne epidemic (1968). The solution obtained is slightly recursive and it may be expressed as a power series in π, the proportion of the infected susceptibles becoming carriers. It generalizes the results of Dietz (1966) and Abakuks (1973) for some special cases of this model.

We establish a sufficient condition for which the expected area under the trajectory of the carrier process is directly proportional to the expected number of removed carriers in the class of carrier-borne, right-shift, epidemic models studied by Severo (1969a). This result generalizes the previous work of Downton (1972) and Jerwood (1974) for some special cases of these models. We use the result to compute expected costs in the carrier-borne model due to Downton (1968) when it is unlikely that all the susceptibles will be infected. We conclude by showing that for the special case considered by Weiss (1965) this treatment of the expected cost is reasonable for populations with a large initial number of susceptibles.

A model for the spread of a carrier-borne disease is considered which allows for individual variability. The solutions are used to study the effect of relaxing the assumption of ‘homogeneous mixing’. It is shown that the mean size of an epidemic outbreak is a minimum when the individuals are homogeneous.

This paper presents the theory of a multivariate birth-and-death process and its representation as a branching process. The bivariate linear birth-and-death process may be used as a model for various epidemic situations involving two types of infective. Various properties of the transient process are discussed and the distribution of epidemic size is investigated. For the case of a disease spread solely by carriers when the two types of infective are carriers and clinical infectives the large population version of a model proposed by Downton (1968) is further developed and shown under appropriate circumstances to closely approximate Downton's model.