As part of an ongoing inventory of the lichenized mycota of the Caxiuanã National Forest, at Ferreira Penna Research Station in the Brazilian Amazon, two species of lichenized fungi are described as new and four new combinations are introduced: Ampliotrema megalostoma (Müll. Arg.) M. Cáceres & Lücking comb. nov., Graphis brachylirellata M. Cáceres & Lücking sp. nov., Malmidea leucogranifera M. Cáceres & Lücking sp. nov., Ocellularia conformalis (Kremp.) M. Cáceres & Lücking comb. nov., Redingeria microspora (Zahlbr.) M. Cáceres & Lücking comb. nov., and Sarcographa megistocarpa (Leight.) M. Cáceres & Lücking comb. nov.