Humanity's challenges have become more acute in recent decades. The international environment has been characterised by rapid change, uncertainty, increased complexity and new trends. Despite the seeming unanimity of the international community in accepting human dignity and human rights as the foundation of a just society, the gap between systems and reality is widening around the world, exacerbated at the same time by globalisation and a liberal, individualistic and consumerist model of democracy. This article seeks to identify a new humanism that can be seen in UNESCO's work in the multifaceted field of culture, with culture as an enabler of sustainable development, peace and economic progress. On the one hand, it examines the confrontation between the politics of recognition and the politics of resentment in dealing with the management of diversity in increasingly complex societies. On the other hand, it analyses the relevance of religion, and particularly the work of the Holy See and successive popes, in culture, public ethics and social cohesion.