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Chapter 5 - The Classification of Polycystic Ovary Syndrome Informed by the International Guideline 2018

Published online by Cambridge University Press:  13 May 2022

By
Robert J. Norman ,
Rhonda Garad  and
Helena Teede
Edited by
Gabor T. Kovacs ,
Bart Fauser  and
Richard S. Legro
Gabor T. Kovacs
Affiliation:
Monash University, Melbourne, Australia
Bart Fauser
Affiliation:
University Medical Center, Utrecht, Netherlands
Richard S. Legro
Affiliation:
Penn State Medical Center, Hershey, PA, USA
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Summary

The definition and classification of polycystic ovary syndrome (PCOS) have been an important but controversial topic for many decades with significant implications for treatment and prognosis. The 2018 international guideline incorporates evidence-based evaluation of the condition together with clinical, consumer, academic and industry contributions to set up the most accepted approach to diagnosis, evaluation and treatment available internationally.

Keywords

polycystic ovary syndrome (PCOS)international guidelinedefinitiontreatmentultrasoundadolescencefertilityclassification
Type
Chapter
Information
Polycystic Ovary Syndrome , pp. 45 - 51
Publisher: Cambridge University Press
Print publication year: 2022

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References

Norman, R. J., Dewailly, D., Legro, R. S. and Hickey, T. E. Polycystic ovary syndrome. Lancet 2007; 370(9588): 685–697. https://doi.org/10.1016/S0140-6736(07)61345-2CrossRefGoogle ScholarPubMed
Azziz, R., Carmina, E., Chen, Z. et al. Polycystic ovary syndrome. Nat Rev Dis Primers 2016; 2: 16057. https://doi.org/10.1038/nrdp.2016.57CrossRefGoogle ScholarPubMed
Azziz, R. Polycystic ovary syndrome. Obstet Gynecol 2018; 132(2): 321–336. https://doi.org/10.1097/AOG.0000000000002698CrossRefGoogle ScholarPubMed
Azziz, R., Dumesic, D. A. and Goodarzi, M. O. Polycystic ovary syndrome: An ancient disorder? Fertil Steril 2011; 95(5): 1544–1548. https://doi.org/10.1016/j.fertnstert.2010.09.032Google Scholar
Adams, J., Polson, D. W. and Franks, S. Prevalence of polycystic ovaries in women with anovulation and idiopathic hirsutism. Br Med J (Clin Res Ed) 1986; 293(6543): 355–359. https://doi.org/10.1136/bmj.293.6543.355CrossRefGoogle ScholarPubMed
Dewailly, D., Lujan, M. E., Carmina, E. et al. Definition and significance of polycystic ovarian morphology: A task force report from the Androgen Excess and Polycystic Ovary Syndrome Society. Hum Reprod Update 2014; 20(3): 334–352. https://doi.org/10.1093/humupd/dmt061CrossRefGoogle ScholarPubMed
Zawadski, J. K. and Dunaif, A. Diagnostic criteria for polycystic ovary syndrome: Towards a rational approach. In Dunaif, A., Givens, J. R., Haseltine, F. P. and Merriam, G. R., eds. Polycystic Ovary Syndrome. Boston, MA: Blackwell Scientific Publications, 1992: 377–384.Google Scholar
The Rotterdam ESHRE/ASRM‐Sponsored PCOS Consensus Workshop Group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). Hum Reprod 2004; 19(1): 41–47. https://doi.org/10.1093/humrep/deh098Google Scholar
Teede, H. J., Misso, M. L., Costello, M. F. et al. Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome. Hum Reprod 2018; 33(9): 1602–1618. https://doi.org/10.1093/humrep/dey256CrossRefGoogle ScholarPubMed
Azziz, R., Carmina, E., Dewailly, D. et al. The Androgen Excess and PCOS Society criteria for the polycystic ovary syndrome: The complete task force report. Fertil Steril 2009; 91(2): 456–488. https://doi.org/10.1016/j.fertnstert.2008.06.035CrossRefGoogle ScholarPubMed
Pena, A. S., Doherty, D. A., Atkinson, H. C., Hickey, M., Norman, R. J. and Hart, R. The majority of irregular menstrual cycles in adolescence are ovulatory: Results of a prospective study. Arch Dis Child 2018; 103(3): 235–239. https://doi.org/10.1136/archdischild-2017-312968CrossRefGoogle ScholarPubMed
Ferriman, D. and Gallwey, J. D. Clinical assessment of body hair growth in women. J Clin Endocrinol Metab 1961; 21: 1440–1447. https://doi.org/10.1210/jcem-21-11-1440CrossRefGoogle ScholarPubMed
Lie Fong, S., Laven, J. S. E., Duhamel, A. and Dewailly, D. Polycystic ovarian morphology and the diagnosis of polycystic ovary syndrome: Redefining threshold levels for follicle count and serum anti-Mullerian hormone using cluster analysis. Hum Reprod 2017; 32(8): 1723–1731. https://doi.org/10.1093/humrep/dex226CrossRefGoogle ScholarPubMed
Teede, H., Misso, M., Tassone, E. C. et al. Anti-Müllerian hormone in PCOS: A review informing international guidelines. Trends Endocrinol Metab 2019 ;30(7): 467–478. https://doi.org/10.1016/j.tem.2019.04.006CrossRefGoogle ScholarPubMed
Zhao, Y. and Qiao, J. Ethnic differences in the phenotypic expression of polycystic ovary syndrome. Steroids 2013; 78(8): 755–760. https://doi.org/10.1016/j.steroids.2013.04.006CrossRefGoogle ScholarPubMed
Papadakis, G., Kandaraki, E. A., Tseniklidi, E., Papalou, O. and Diamanti-Kandarakis, E. Polycystic ovary syndrome and NC-CAH: Distinct characteristics and common findings. A systematic review. Front Endocrinol (Lausanne) 2019; 10: 388. https://doi.org/10.3389/fendo.2019.00388Google Scholar
Pena, A. S., Witchel, S. F., Hoeger, K. M. et al. Adolescent polycystic ovary syndrome according to the international evidence-based guideline. BMC Med 2020; 18(1): 72. https://doi.org/10.1186/s12916-020-01516-xGoogle Scholar

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