Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-78c5997874-m6dg7 Total loading time: 0 Render date: 2024-11-08T02:35:19.321Z Has data issue: false hasContentIssue false

Chapter 19 - Deep-brain stimulation of the subthalamic nucleus in the management of Parkinson's disease

from Section III - Surgical Management of Parkinson's Disease

Published online by Cambridge University Press:  05 March 2016

By
David A. Schmerler ,
Alberto J. Espay  and
Andrew P. Duker
Edited by
Néstor Gálvez-Jiménez ,
Hubert H. Fernandez ,
Alberto J. Espay  and
Susan H. Fox
Néstor Gálvez-Jiménez
Affiliation:
Cleveland Clinic, Florida
Hubert H. Fernandez
Affiliation:
Cleveland Clinic, Ohio
Alberto J. Espay
Affiliation:
University of Cincinnati
Susan H. Fox
Affiliation:
Toronto Western Hospital
Get access

Summary

A summary is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Chapter
Information
Parkinson's Disease
Current and Future Therapeutics and Clinical Trials
 , pp. 195 - 205
Publisher: Cambridge University Press
Print publication year: 2016

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Hullay, J, Velok, J, Gombi, R, Boczan, G. Subthalamotomy in Parkinson's disease. Confin Neurol 1970; 32: 345–8.CrossRefGoogle ScholarPubMed
Bechtereva, NP, Bondartchuk, AN, Smirnov, VM, Meliutcheva, LA, Shandurina, AN. Method of electrostimulation of the deep brain structures in treatment of some chronic diseases. Confin Neurol 1975; 37: 136–40.CrossRefGoogle ScholarPubMed
Benabid, AL, Pollak, P, Louveau, A, Henry, S, de Rougemont, J. Combined (thalamotomy and stimulation) stereotactic surgery of the VIM thalamic nucleus for bilateral Parkinson disease. Appl Neurophysiol 1987; 50: 344–6.Google Scholar
Albin, RL, Young, AB, Penney, JB. The functional anatomy of basal ganglia disorders. Trends Neurosci 1989; 12: 366–75.Google Scholar
Benazzouz, A, Gross, C, Feger, J, Boraud, T, Bioulac, B. Reversal of rigidity and improvement in motor performance by subthalamic high-frequency stimulation in MPTP-treated monkeys. Eur J Neurosci 1993; 5: 382–9.Google Scholar
Limousin, P, Pollak, P, Benazzouz, A, et al. Effect of parkinsonian signs and symptoms of bilateral subthalamic nucleus stimulation. Lancet 1995; 345: 91–5.CrossRefGoogle ScholarPubMed
Schrag, A, Jahanshahi, M, Quinn, N. What contributes to quality of life in patients with Parkinson's disease? J Neurol Neurosurg Psychiatry 2000; 69: 308–12.Google Scholar
Olanow, CW, Obeso, JA, Stocchi, F. Continuous dopamine-receptor treatment of Parkinson's disease: scientific rationale and clinical implications. Lancet Neurol 2006; 5: 677–87.Google Scholar
Goetz, CG, Poewe, W, Rascol, O, Sampaio, C. Evidence-based medical review update: pharmacological and surgical treatments of Parkinson's disease: 2001 to 2004. Mov Disord 2005; 20: 523–39.Google Scholar
Deuschl, G, Schade-Brittinger, C, Krack, P, et al. A randomized trial of deep-brain stimulation for Parkinson's disease. N Engl J Med 2006; 355: 896–908.Google Scholar
Limousin, P, Krack, P, Pollak, P, et al. Electrical stimulation of the subthalamic nucleus in advanced Parkinson's disease. N Engl J Med 1998; 339: 1105–11.CrossRefGoogle ScholarPubMed
Deep-Brain Stimulation for Parkinson's Disease Study Group. Deep-brain stimulation of the subthalamic nucleus or the pars interna of the globus pallidus in Parkinson's disease. N Engl J Med 2001; 345: 956–63.CrossRefGoogle Scholar
Krack, P, Batir, A, Van Blercom, N, et al. Five-year follow-up of bilateral stimulation of the subthalamic nucleus in advanced Parkinson's disease. N Engl J Med 2003; 349: 1925–34.CrossRefGoogle ScholarPubMed
Lang, AE. Surgery for Parkinson disease: a critical evaluation of the state of the art. Arch Neurol 2000; 57: 1118–25.Google Scholar
Langston, JW, Widner, H, Goetz, CG, et al. Core assessment program for intracerebral transplantations (CAPIT). Mov Disord 1992; 7: 2–13.Google Scholar
Defer, GL, Widner, H, Marie, RM, Remy, P, Levivier, M. Core assessment program for surgical interventional therapies in Parkinson's disease (CAPSIT-PD). Mov Disord 1999; 14: 572–84.Google Scholar
Lang, AE, Widner, H. Deep brain stimulation for Parkinson's disease: patient selection and evaluation. Mov Disord 2002; 17 (Suppl. 3): S94–101.CrossRefGoogle ScholarPubMed
Duker, AP, Espay, AJ. Surgical treatment of Parkinson disease: past, present, and future. Neurol Clin 2013; 31: 799–808.Google Scholar
Shih, LC, Tarsy, D. Deep brain stimulation for the treatment of atypical parkinsonism. Mov Disord 2007; 22: 2149–55.Google Scholar
Follett, KA, Weaver, FM, Stern, M, et al. Pallidal versus subthalamic deep-brain stimulation for Parkinson's disease. N Engl J Med 2010; 362: 2077–91.Google Scholar
Hasegawa, H, Samuel, M, Douiri, A, Ashkan, K. Patients’ expectations in subthalamic nucleus deep brain stimulation surgery for Parkinson disease. World Neurosurg 2014; 82: 1295–9.CrossRefGoogle ScholarPubMed
Marinus, J, Visser, M, Martinez-Martin, P, van Hilten, JJ, Stiggelbout, AM. A short psychosocial questionnaire for patients with Parkinson's disease: the SCOPA-PS. J Clin Epidemiol 2003; 56: 61–7.Google Scholar
Schuepbach, WM, Rau, J, Knudsen, K, et al. Neurostimulation for Parkinson's disease with early motor complications. N Engl J Med 2013; 368: 610–22.Google Scholar
Mestre, TA, Espay, AJ, Marras, C, et al. Subthalamic nucleus-deep brain stimulation for early motor complications in Parkinson's disease – the EARLYSTIM trial: early is not always better. Mov Disord 2014; 29: 1751–6.Google Scholar
Charles, D, Konrad, PE, Neimat, JS, et al. Subthalamic nucleus deep brain stimulation in early stage Parkinson's disease. Parkinsonism Relat Disord 2014; 20: 731–7.Google Scholar
Hilker, R, Portman, AT, Voges, J, et al. Disease progression continues in patients with advanced Parkinson's disease and effective subthalamic nucleus stimulation. J Neurol Neurosurg Psychiatry 2005; 76: 1217–21.CrossRefGoogle ScholarPubMed
Lilleeng, B, Bronnick, K, Toft, M, Dietrichs, E, Larsen, JP. Progression and survival in Parkinson's disease with subthalamic nucleus stimulation. Acta Neurol Scand 2014; 130: 292–8.Google Scholar
Fasano, A, Romito, LM, Daniele, A, et al. Motor and cognitive outcome in patients with Parkinson's disease 8 years after subthalamic implants. Brain 2010; 133: 2664–76.Google Scholar
Castrioto, A, Lozano, AM, Poon, YY, et al. Ten-year outcome of subthalamic stimulation in Parkinson disease: a blinded evaluation. Arch Neurol 2011; 68: 1550–6.Google Scholar
Bejjani, BP, Dormont, D, Pidoux, B, et al. Bilateral subthalamic stimulation for Parkinson's disease by using three-dimensional stereotactic magnetic resonance imaging and electrophysiological guidance. J Neurosurg 2000; 92: 615–25.Google Scholar
Machado, A, Rezai, AR, Kopell, BH, et al. Deep brain stimulation for Parkinson's disease: surgical technique and perioperative management. Mov Disord 2006; 21 (Suppl. 14): S247–58.Google Scholar
Benabid, AL, Chabardès, S, Mitrofanis, J, Pollak, P. Deep brain stimulation of the subthalamic nucleus for the treatment of Parkinson's disease. Lancet Neurology 2009; 8: 67–81.Google Scholar
Taba, HA, Wu, SS, Foote, KD, et al. A closer look at unilateral versus bilateral deep brain stimulation: results of the National Institutes of Health COMPARE cohort. J Neurosurg 2010; 113: 1224–9.Google Scholar
Bastian, AJ, Kelly, VE, Revilla, FJ, Perlmutter, JS, Mink, JW. Different effects of unilateral versus bilateral subthalamic nucleus stimulation on walking and reaching in Parkinson's disease. Mov Disord 2003; 18: 1000–7.Google Scholar
Kleiner-Fisman, G, Herzog, J, Fisman, DN, et al. Subthalamic nucleus deep brain stimulation: summary and meta-analysis of outcomes. Mov Disord 2006;21 (Suppl. 14): S290–304.CrossRefGoogle ScholarPubMed
Weaver, FM, Follett, K, Stern, M, et al. Bilateral deep brain stimulation vs best medical therapy for patients with advanced Parkinson disease: a randomized controlled trial. JAMA 2009; 301: 63–73.Google Scholar
Williams, A, Gill, S, Varma, T, et al. Deep brain stimulation plus best medical therapy versus best medical therapy alone for advanced Parkinson's disease (PD SURG trial): a randomised, open-label trial. Lancet Neurol 2010; 9: 581–91.Google Scholar
Moro, E, Scerrati, M, Romito, LM, et al. Chronic subthalamic nucleus stimulation reduces medication requirements in Parkinson's disease. Neurology 1999; 53: 85–90.Google Scholar
Kumar, R, Lozano, AM, Kim, YJ, et al. Double-blind evaluation of subthalamic nucleus deep brain stimulation in advanced Parkinson's disease. Neurology 1998; 51: 850–5.Google Scholar
Pinto, S, Gentil, M, Krack, P, et al. Changes induced by levodopa and subthalamic nucleus stimulation on parkinsonian speech. Mov Disord 2005; 20: 1507–15.CrossRefGoogle ScholarPubMed
Parsons, TD, Rogers, SA, Braaten, AJ, Woods, SP, Tröster, AI. Cognitive sequelae of subthalamic nucleus deep brain stimulation in Parkinson's disease: a meta-analysis. Lancet Neurol 2006; 5: 578–88.Google Scholar
Moro, E, Esselink, RJ, Xie, J, et al. The impact on Parkinson's disease of electrical parameter settings in STN stimulation. Neurology 2002; 59: 706–13.Google Scholar
Moreau, C, Defebvre, L, Destée, A, et al. STN-DBS frequency effects on freezing of gait in advanced Parkinson disease. Neurology 2008; 71: 80–4.Google Scholar
Eusebio, A, Chen, CC, Lu, CS, et al. Effects of low-frequency stimulation of the subthalamic nucleus on movement in Parkinson's disease. Exp Neurol 2008; 209: 125–30.Google Scholar
Meissner, W, Leblois, A, Hansel, D, et al. Subthalamic high frequency stimulation resets subthalamic firing and reduces abnormal oscillations. Brain 2005; 128: 2372–82.Google Scholar
Brown, P. Oscillatory nature of human basal ganglia activity: relationship to the pathophysiology of Parkinson's disease. Mov Disord 2003; 18: 357–63.Google Scholar
Bronte-Stewart, H, Barberini, C, Koop, MM, Hill, et al. The STN beta-band profile in Parkinson's disease is stationary and shows prolonged attenuation after deep brain stimulation. Exp Neurol 2009; 215: 20–8.Google Scholar
Rossi, L, Marceglia, S, Foffani, G, et al. Subthalamic local field potential oscillations during ongoing deep brain stimulation in Parkinson's disease. Brain Res Bull 2008; 76: 512–21.Google Scholar
Priori, A, Ardolino, G, Marceglia, S, et al. Low-frequency subthalamic oscillations increase after deep brain stimulation in Parkinson's disease. Brain Res Bull 2006; 71: 149–54.Google Scholar
Giannicola, G, Rosa, M, Servello, D, et al. Subthalamic local field potentials after seven-year deep brain stimulation in Parkinson's disease. Exp Neurol 2012; 237: 312–7.Google Scholar
Odekerken, VJ, van Laar, T, Staal, MJ, et al. Subthalamic nucleus versus globus pallidus bilateral deep brain stimulation for advanced Parkinson's disease (NSTAPS study): a randomised controlled trial. Lancet Neurol 2013; 12: 37–44.Google Scholar
Guridi, J, Rodriguez-Oroz, MC, Alegre, M, Obeso, JA. Hardware complications in deep brain stimulation: electrode impedance and loss of clinical benefit. Parkinsonism Relat Disord 2012; 18: 765–9.Google Scholar
Barichella, M, Marczewska, AM, Mariani, C, et al. Body weight gain rate in patients with Parkinson's disease and deep brain stimulation. Mov Disord 2003; 18: 1337–40.Google Scholar
Ruzicka, E, Novakova, L, Jech, R, et al. Decrease in blood cortisol corresponds to weight gain following deep brain stimulation of the subthalamic nucleus in Parkinson's disease. Stereotact Funct Neurosurg 2012; 90: 410–11.Google Scholar
Ruzicka, F, Jech, R, Novakova, L, et al. Chronic stress-like syndrome as a consequence of medial site subthalamic stimulation in Parkinson's disease. Psychoneuroendocrinology 2015; 52: 302–10.Google Scholar
Welter, ML, Schüpbach, M, Czernecki, V, et al. Optimal target localization for subthalamic stimulation in patients with Parkinson disease. Neurology 2014; 82: 1352–61.CrossRefGoogle ScholarPubMed
Doshi, PK, Chhaya, N, Bhatt, MH. Depression leading to attempted suicide after bilateral subthalamic nucleus stimulation for Parkinson's disease. Mov Disord 2002; 17: 1084–5.Google Scholar
Voon, V, Krack, P, Lang, AE, et al. A multicentre study on suicide outcomes following subthalamic stimulation for Parkinson's disease. Brain 2008; 131: 2720–8.Google Scholar
Schüpbach, M, Gargiulo, M, Welter, ML, et al. Neurosurgery in Parkinson disease: a distressed mind in a repaired body? Neurology 2006; 66: 1811–16.Google Scholar
Voon, V, Kubu, C, Krack, P, Houeto, JL, Tröster, AI. Deep brain stimulation: neuropsychological and neuropsychiatric issues. Mov Disord 2006; 21 (Suppl. 14): S305–27.Google Scholar
Ulla, M, Thobois, S, Llorca, PM, et al. Contact dependent reproducible hypomania induced by deep brain stimulation in Parkinson's disease: clinical, anatomical and functional imaging study. J Neurol Neurosurg Psychiatry 2011; 82: 607–14.Google Scholar
Mallet, L, Schüpbach, M, N’Diaye, K, et al. Stimulation of subterritories of the subthalamic nucleus reveals its role in the integration of the emotional and motor aspects of behavior. Proc Natl Acad Sci U S A 2007; 104: 10661–6.CrossRefGoogle ScholarPubMed
Spieles-Engemann, AL, Behbehani, MM, Collier, TJ, et al. Stimulation of the rat subthalamic nucleus is neuroprotective following significant nigral dopamine neuron loss. Neurobiol Dis 2010; 39: 105–15.Google Scholar
Wallace, BA, Ashkan, K, Heise, CE, et al. Survival of midbrain dopaminergic cells after lesion or deep brain stimulation of the subthalamic nucleus in MPTP-treated monkeys. Brain 2007; 130: 2129–45.Google Scholar
Marceglia, S, Rossi, L, Foffani, G, et al. Basal ganglia local field potentials: applications in the development of new deep brain stimulation devices for movement disorders. Expert Rev Med Devices 2007; 4: 605–14.Google Scholar
Rosin, B, Slovik, M, Mitelman, R, et al. Closed-loop deep brain stimulation is superior in ameliorating parkinsonism. Neuron 2011; 72: 370–84.Google Scholar
Martens, HC, Toader, E, Decre, MM, et al. Spatial steering of deep brain stimulation volumes using a novel lead design. Clin Neurophysiol 2011; 122: 558–66.Google Scholar
Chaturvedi, A, Foutz, TJ, McIntyre, CC. Current steering to activate targeted neural pathways during deep brain stimulation of the subthalamic region. Brain Stimul 2012; 5: 369–77.Google Scholar
Benabid, AL, Pollak, P, Gao, D, et al. Chronic electrical stimulation of the ventralis intermedius nucleus of the thalamus as a treatment of movement disorders. J Neurosurg 1996; 84: 203–14.Google Scholar
Rehncrona, S, Johnels, B, Widner, H, et al. Long-term efficacy of thalamic deep brain stimulation for tremor: double-blind assessments. Mov Disord 2003; 18: 163–70.Google Scholar
Stefani, A, Lozano, AM, Peppe, A, et al. Bilateral deep brain stimulation of the pedunculopontine and subthalamic nuclei in severe Parkinson's disease. Brain 2007; 130: 1596–607.Google Scholar
Okun, MS, Fernandez, HH, Wu, SS, et al. Cognition and mood in Parkinson's disease in subthalamic nucleus versus globus pallidus interna deep brain stimulation: the COMPARE trial. Ann Neurol 2009; 65: 586–95.Google Scholar
Moro, E, Hamani, C, Poon, YY, et al. Unilateral pedunculopontine stimulation improves falls in Parkinson's disease. Brain 2010; 133: 215–24.Google Scholar

Save book to Kindle

To save this book to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×