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Published online by Cambridge University Press: 21 November 2024
First described by seventeenth-century English anatomist and physician Thomas Willis, restless leg syndrome, a disorder he termed “unquietness,” is mainly characterized by the chronic symptoms of involuntary leg movements commonly caused by uncomfortable leg parasthesias (tingling, stretching, and crawling sensation on skin) and the uncontrollable urge to move, all of which are relieved with movement. This disorder was later more fully studied and described by twentieth-century Swedish neurologist Karl Axel Ekbom, who eventually coined the term “restless leg syndrome,” though some still refer to this disorder as “Willis–Ekbom Disease.”
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