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Chapter 1 - In Vitro Fertilization and Micromanipulation

The History That Changed the Treatment of Male Factor Infertility

Published online by Cambridge University Press:  02 December 2021

Gianpiero D. Palermo
Affiliation:
Cornell Institute of Reproductive Medicine, New York
Zsolt Peter Nagy
Affiliation:
Reproductive Biology Associates, Atlanta, GA
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Summary

This chapter reviews the short period between the exploration of male factor treatment using standard in vitro fertilization in small clinical series initiated in the early 1980s and subsequent development of micromanipulation technologies before ICSI. Instrumental fertilization was developed to improve the incidence of fertilization as well as apply the technology to patients with extreme male factor. A decade later, the Brussels team introduced ICSI, with fertilization rates that were at least twice as high compared to those of earlier micromanipulation approaches. A short history of male factor infertility and the biased views medical specialists showed in favor of solely treating the female partner is discussed in the context of discovery of gametes and the process of fertilization in the nineteenth century. The condition of infertility in men was basically considered untreatable until the 1970s, but as a clinical concept, it was also largely ignored. The possibility of using IVF for effectively treating less fertile men was considered experimental in 1980. The technical and physiological background as well as ambiguous animal models before clinical ICSI are evaluated particularly in the context of why early micromanipulation methods such as partial zona dissection and sub-zonal sperm insertion ultimately failed.

Type
Chapter
Information
Manual of Intracytoplasmic Sperm Injection in Human Assisted Reproduction
With Other Advanced Micromanipulation Techniques to Edit the Genetic and Cytoplasmic Content of the Oocyte
, pp. 1 - 10
Publisher: Cambridge University Press
Print publication year: 2021

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References

Von Baer, KE. De Ovi Mammalium et Hominis Genesi (“On the Mammalian Egg and the Origin of Man”). Leipzig,Germany: Leopold Voss; 1827.Google Scholar
Clift, D, Schuh, M. Restarting life: fertilization and the transition from meiosis to mitosis. Nat Rev Mol Cell Biol. 2013;14:549562.CrossRefGoogle ScholarPubMed
Macomber, D, Sanders, MB. The spermatozoa count. Its value in the diagnosis, prognosis and treatment of sterility. N Engl J Med. 1929;200:981984.Google Scholar
Andrade-Rocha, FT. On the origins of the semen analysis: a close relationship with the history of the reproductive medicine. J Hum Reprod Sci. 2017;10:242255.CrossRefGoogle ScholarPubMed
Hotchkiss, RS. Fertility in Men. Philadelphia: JB Lippincott Company; 1944.Google Scholar
MacLeod, J. Semen quality in one thousand men of known fertility and in eight hundred cases of infertile marriage. Fertil Steril. 1951;2:115139.CrossRefGoogle Scholar
Tyler, ET, Singher, HO. Male infertility; status of treatment, prevention and current research. J Am Med Assoc. 1956;160:9197.CrossRefGoogle ScholarPubMed
Polge, C, Smith, AU, Parkes, AS. Revival of spermatozoa after vitrification and dehydration at low temperatures. Nature 1949;15:666.CrossRefGoogle Scholar
Bunge, Rg, Sherman, JK. Fertilizing capacity of frozen human spermatozoa. Nature. 1953;172:767768.Google Scholar
Austin, CR. Observation on the penetration of sperm into the mammalian egg. Aust J Sci Res B. 1951;4:581596.Google Scholar
Chang, MC. Fertilizing capacity of spermatozoa deposited in the fallopian tubes. Nature. 1951;168:697698.Google Scholar
Sigman, M, Baazeem, A, Zini, A. Semen analysis and sperm function assays: what do they mean? Semin Reprod Med. 2009;27:115123.CrossRefGoogle ScholarPubMed
DeJonge, C. Semen analysis: looking for an upgrade in class. Fertil Steril. 2012;97:260266.CrossRefGoogle Scholar
Edwards, RG, Steptoe, PC. Birth after the reimplantation of a human embryo. Lancet. 1978;312:366.Google Scholar
Gordon, JW, Talansky, BE. Assisted fertilization by zona drilling: a mouse model for correction of oligospermia. J Exp Zool. 1986;239:347354.Google Scholar
Mann, JR. Full term development of mouse eggs fertilized by a spermatozoon microinjected under the zona pellucida. Biol Reprod. 1988;38:10771083.Google Scholar
Cohen, J, Malter, H, Fehilly, C, Wright, G, Elsner, C, Kort, H, Massey, J. Implantation of embryos after partial opening of oocyte zona pellucida to facilitate sperm penetration. Lancet. 1988;2:162.CrossRefGoogle ScholarPubMed
Ng, SC, Bongso, A, Ratnam, SS, Sathananthan, H, Chan, CL, Wong, PC, Hagglund, L, Anandakumar, C, Wong, YC, Goh, VH. Pregnancy after transfer of sperm under zona. Lancet. 1988;2:790.Google Scholar
Fishel, S, Antinori, S, Jackson, P, Johnson, J, Lisi, F, Chiariello, F, Versaci, C. Twin birth after subzonal insemination. Lancet. 1990;335:722723.Google Scholar
Palermo, G, Joris, H, Devroey, P, Van Steirteghem, AC. Pregnancies after intracytoplasmic injection of single spermatozoon into an oocyte. Lancet. 1992;340:1718.CrossRefGoogle ScholarPubMed
Sennert, D : Practical Physick. 4th Book. Published by Cole P Cornhill printing press. England, 1664.Google Scholar
Kumar, N, Singh, AK. Trends of male factor infertility, an important cause of infertility: a review of literature. J Hum Reprod Sci. 2015;8:191196.Google Scholar
Edwards, RG, Purdy, JM (eds). Human Conception in Vitro. London: Academic Press; 1982.Google Scholar
Mahadevan, MM, Trounson, AO, Leeton, JF. The relationship of tubal blockage, infertility of unknown cause, suspected male infertility, and endometriosis to success of in vitro fertilization and embryo transfer. Fertil Steril. 1983;40:755762.CrossRefGoogle ScholarPubMed
Mahadevan, MM, Leeton, JF, Trounson, AO, Wood, C. Successful use of in vitro fertilization for patients with persisting low-quality semen. Ann N Y Acad Sci. 1985;442:293300.CrossRefGoogle ScholarPubMed
Aafjes, JH, van der Vijver, JC, Schenck, PE. The duration of infertility: an important datum for the fertility prognosis of men with semen abnormalities. Fertil Steril. 1978;30:423425.Google Scholar
Cohen, J, Malter, H, Elsner, C, Kort, H, Massey, J, Mayer, MP. Immunosuppression supports implantation of zona pellucida dissected human embryos. Fertil Steril. 1990;53:662665.Google Scholar
Cohen, J, Alikani, M, Trowbridge, J, Rosenwaks, Z. Implantation enhancement by selective assisted hatching using zona drilling of human embryos with poor prognosis. Hum Reprod. 1992;7:685691.Google Scholar
Vandekerckhove, P, O’Donovan, PA, Lilford, RJ, Harada, TW. Infertility treatment: from cookery to science. The epidemiology of randomised controlled trials. Br J Obstet Gynaecol. 1993;100:10051036.Google Scholar
Haldane, JBS. Daedalus, or Science and the Future. A Paper read to the Heretics, Cambridge, on February 4, 1923. Pp. vii + 93. London: Kegan Paul and Co., Ltd.; 1924.Google Scholar
Rock, J, Menkin, MF. In vitro fertilization and cleavage of human ovarian eggs. Science. 1944;100:105107.Google Scholar
Edwards, RG, Steptoe, PC. A Matter of Life: The Story of IVF: A Medical Breakthrough. London, UK: Finestride and Crownchime; 1980.Google Scholar
Edwards, RG. Maturation in vitro of human ovarian oocytes. Lancet. 1965;286:926929.Google Scholar
Edwards, RG, Steptoe, PC, Purdy, JM. Establishing full-term human pregnancies using cleaving embryos grown in vitro. Br J Obstet Gynaecol. 1980;87:737756.Google Scholar
Catford, SR, McLachlan, RI, O’Bryan, MK, Halliday, JL. Long-term follow-up of intra-cytoplasmic sperm injection-conceived offspring compared with in vitro fertilization-conceived offspring: a systematic review of health outcomes beyond the neonatal period. Andrology. 2017;5:610621.Google Scholar
Wisanto, A, Magnus, M, Bonduelle, M, Liu, J, Camus, M, Tournaye, H, Liebaers, I, Van Steirteghem, AC, Devroey, P. Obstetric outcome of 424 pregnancies after intracytoplasmic sperm injection. Hum Reprod. 1995;10:27132718.Google Scholar
Cohen, J, Fehilly, CB, Fishel, SB, Edwards, RG, Hewitt, J, Rowland, GF, Steptoe, PC, Webster, J. Male infertility successfully treated by in-vitro fertilisation. Lancet. 1984;1:12391240.Google Scholar
Lopata, A. Successes and failures in human in vitro fertilization. Nature. 1980;288:642643.Google Scholar
Trounson, AO, Leeton, JF, Wood, C, Webb, J, Kovacs, G. The investigation of idiopathic infertility by in vitro fertilization. Fertil Steril. 1980;34:431438.Google Scholar
Cohen, J, Edwards, R, Fehilly, C, Fishel, S, Hewitt, J, Purdy, J, Rowland, G, Steptoe, P, Webster, J. In vitro fertilization: a treatment for male infertility. Fertil Steril. 1985 43:422432.CrossRefGoogle ScholarPubMed
Kanwar, KC, Yanagimachi, R, Lopata, A. Effects of human seminal plasma on fertilizing capacity of human spermatozoa. Fertil Steril. 1979;31:321327.Google Scholar
Mortimer, D. Sperm preparation methods. J Androl. 2000;21:357366.Google Scholar
Hyne, RV, Stojanoff, A, Clarke, GN, Lopata, A, Johnston, WI. Pregnancy from in vitro fertilization of human eggs after separation of motile spermatozoa by density gradient centrifugation. Fertil Steril. 1986;45:9396.Google Scholar
Palini, S, Stefani, S, Primiterra, M, Benedetti, S, Barone, S, Carli, L, Vaccari, E, Murat, U, Feichtinger, W. Comparison of in vitro fertilization outcomes in ICSI cycles after human sperm preparation by density gradient centrifugation and direct micro swim-up without centrifugation. JBRA Assist Reprod. 2017;21:8993.Google Scholar
Matson, PL, Turner, SR, Yovich, JM, Tuvik, AI, Yovich, JL. Oligospermic infertility treated by in-vitro fertilization. Aust N Z J Obstet Gynaecol. 1986;26:8487.CrossRefGoogle ScholarPubMed
Uehara, T, Yanagimachi, R. Microsurgical injection of spermatozoa into hamster eggs with subsequent transformation of sperm nuclei into male pronuclei. Biol Reprod. 1976;15:467470.CrossRefGoogle ScholarPubMed
Markert, CL. Fertilization of mammalian eggs by sperm injection. J Exp Zool. 1983;228:195201.Google Scholar
Gordon, JW, Ruddle, FH. Integration and stable germ line transmission of genes injected into mouse pronuclei. Science. 1981;214:12441246.Google Scholar
Yanagimachi, R, Yanagimachi, H, Rogers, BJ. The use of zona-free animal ova as a test-system for the assessment of the fertilizing capacity of human spermatozoa. Biol Reprod. 1976;15:471476.Google Scholar
Whittingham, DG. Fertilization of mouse eggs in vitro. Nature. 1968;220:592593.CrossRefGoogle ScholarPubMed
Kimura, Y, Yanagimachi, R. Intracytoplasmic sperm injection in the mouse. Biol Reprod. 1995;52:709720.Google Scholar
Laws-King, A, Trounson, A, Sathananthan, H, Kola, I. Fertilization of human oocytes by microinjection of a single spermatozoon under the zona pellucida. Fertil Steril. 1987;48:637642.Google Scholar
Neev, J, Gonzalez, A, Licciardi, F, Licciardi, F, Alikani, M, Tadir, Y, Berns, M, Cohen, J. Opening of the mouse zona pellucida by laser without a micromanipulator. Hum Reprod. 1993;8:939944.Google Scholar
Metka, M, Haromy, T, Huber, J, Schurz, B. Apparative Insemination mit Hilfe des Mikromanipulators (“Artificial insemination using a micromanipulator”). Fertilität 1985;1:4144.Google Scholar
Keefer, CL. Fertilization by sperm injection in the rabbit. Gamete Res. 1989;22:5969.Google Scholar
Iritani, A, Utsumi, K, Miyake, M, Hosoi, Y, Saeki, K. In vitro fertilization by a routine method and micromanipulation. Ann New York Acad Sci 1988;541:583590.Google Scholar
Lanzendorf, SE, Maloney, MK, Veeck, LL, Slusser, J, Hodgen, GD, Rosenwaks, Z. A preclinical evaluation of pronuclear formation by microinjection of human spermatozoa into human oocytes. Fertil Steril. 1988;49 835842.Google Scholar
Malter, HE, Cohen, J. Partial zona dissection of the human oocyte: a nontraumatic method using micromanipulation to assist zona pellucida penetration. Fertil Steril. 1989;51:139148.Google Scholar
Malter, HE. Micromanipulation in assisted reproductive technology. Reprod Biomed Online. 2016;32:339347.CrossRefGoogle ScholarPubMed
Handyside, AH, Kontogianni, EH, Hardy, K, Winston, RM. Pregnancies from biopsied human preimplantation embryos sexed by Y-specific DNA amplification. Nature. 1990;344:768770.Google Scholar
Cohen, J, Elsner, C, Kort, H, Malter, H, Massey, J, Mayer, MP, Wiemer, K. Impairment of the hatching process following IVF in the human and improvement of implantation by assisting hatching using micromanipulation. Hum Reprod. 1990;5:713.Google Scholar
Gordon, JW, Grunfeld, L, Talansky, BE, Garrisi, GJ, Richards, C, Wiczyk, H, Rappaport, D, Navot, D, Laufer, N. The human oocyte blocks polyspermy at the zona pellucida. Presented at the Forty-Fourth Annual Meeting of The American Fertility Society. Atlanta, GA, American Fertility Society, Birmingham;1988:1013 (AL, in the Program Supplement, 1988).Google ScholarPubMed

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