Book contents
- Frontmatter
- Contents
- About the authors
- Preface
- Acknowledgements
- Abbreviations
- 1 Epidemiology and initial assessment
- 2 Male factor infertility
- 3 Ovulatory disorders
- 4 Tubal infertility
- 5 Endometriosis-related infertility
- 6 Uterine factors in infertility
- 7 Unexplained infertility
- 8 Assisted reproduction – preparation and work-up of couples
- 9 Assisted reproduction – clinical and laboratory procedures
- Index
4 - Tubal infertility
Published online by Cambridge University Press: 05 June 2014
- Frontmatter
- Contents
- About the authors
- Preface
- Acknowledgements
- Abbreviations
- 1 Epidemiology and initial assessment
- 2 Male factor infertility
- 3 Ovulatory disorders
- 4 Tubal infertility
- 5 Endometriosis-related infertility
- 6 Uterine factors in infertility
- 7 Unexplained infertility
- 8 Assisted reproduction – preparation and work-up of couples
- 9 Assisted reproduction – clinical and laboratory procedures
- Index
Summary
Introduction
Fallopian tube damage accounts for 25–35% of infertility in women. In approximately three-quarters of cases the damage results from sexually transmitted infection (STIs) but tubal damage can also be as a result of pelvic surgery. The fallopian tubes play an essential role in conception, and tubal pathologies such as peritubal adhesions, proximal and/or distal tubal blockage, hydrosalpinx formation or endosalpingeal damage all have an adverse impact on fertility. The management of tubal disease depends on the initial pathological process and the severity of damage. In vitro fertilisation (IVF) remains the main treatment strategy for women with severely damaged fallopian tubes. Surgery can be useful in selected cases of tubal infertility and may have a complementary role for some women undergoing IVF. This chapter discusses these processes further but initially the basic anatomy of these remarkable but vulnerable structures is reviewed.
Anatomy
The fallopian tubes are derived from the müllerian ducts and are formed at the 6th week of embryological development. They comprise the isthmus, ampulla and infundibulum, with the latter's fimbrial end essential for picking up an ovum from the rupturing ovarian follicle. Each tube is about 10 cm long (range 7–14 cm). The lumen varies in diameter from 0.1 mm at the isthmus to 1 cm at the distal end of the ampulla. The columnar epithelium lining the tubes includes two different cell types: ciliated cells concentrated at the distal end of the tube and secretory cells at the ampullary region.
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- Management of Infertility for the MRCOG and Beyond , pp. 45 - 56Publisher: Cambridge University PressPrint publication year: 2014