Book contents
- Frontmatter
- Contents
- FOREWORD
- ACKNOWLEDGMENTS
- CONTRIBUTORS
- PART I PRINCIPLES OF ONCOLOGY
- PART II PRINCIPLES OF IMAGE-GUIDED THERAPIES
- PART III ORGAN-SPECIFIC CANCERS
- 9 Hepatocellular Carcinoma: Epidemiology, Pathology, Diagnosis and Screening
- 10 Staging Systems for Hepatocellular Carcinoma
- 11 Hepatocellular Carcinoma: Medical Management
- 12 Surgical Management (Resection)
- 13 Liver Transplantation for Hepatocellular Carcinoma
- 14 Image-guided Ablation of Hepatocellular Carcinoma
- 15 Embolization of Liver Tumors: Anatomy
- 16 Transcatheter Arterial Chemoembolization: Technique and Future Potential
- 17 New Concepts in Targeting and Imaging Liver Cancer
- 18 Intrahepatic Cholangiocarcinoma
- 19 Medical Management of Colorectal Liver Metastasis
- 20 Surgical Resection of Hepatic Metastases
- 21 Clinical Management of Patients with Colorectal Liver Metastasis Using Hepatic Arterial Infusion
- 22 Colorectal Metastases: Ablation
- 23 Colorectal Metastases: Chemoembolization
- 24 Radioembolization with 90Yttrium Microspheres for Colorectal Liver Metastases
- 25 Carcinoid and Related Neuroendocrine Tumors
- 26 Interventional Radiology for the Treatment of Liver Metastases from Neuroendocrine Tumors
- 27 Immunoembolization for Melanoma
- 28 Preoperative Portal Vein Embolization
- 29 Cancer of the Extrahepatic Bile Ducts and the Gallbladder: Surgical Management
- 30 Extrahepatic Biliary Cancer: High Dose Rate Brachytherapy and Photodynamic Therapy
- 31 Extrahepatic Biliary Cancer/Biliary Drainage
- 32 Surgical and Medical Treatment
- 33 Percutaneous Renal Ablation
- 34 Embolotherapy in the Management of Renal Cell Carcinoma
- 35 Epidemiology, Diagnosis, Staging and the Medical-Surgical Management of Lung Cancers
- 36 Image-guided Ablation in the Thorax
- 37 Interventional Treatment Methods for Unresectable Lung Tumors
- 38 Interventional Neuroradiology in Head and Neck Oncology
- 39 Percutaneous Ablation of Painful Metastases Involving Bone
- 40 Intra-arterial Therapy for Sarcomas
- 41 Prostate Cryoablation: A Role for the Radiologist in Treating Prostate Cancer?
- PART IV SPECIALIZED INTERVENTIONAL TECHNIQUES IN CANCER CARE
- INDEX
- Plate section
- References
36 - Image-guided Ablation in the Thorax
from PART III - ORGAN-SPECIFIC CANCERS
Published online by Cambridge University Press: 18 May 2010
- Frontmatter
- Contents
- FOREWORD
- ACKNOWLEDGMENTS
- CONTRIBUTORS
- PART I PRINCIPLES OF ONCOLOGY
- PART II PRINCIPLES OF IMAGE-GUIDED THERAPIES
- PART III ORGAN-SPECIFIC CANCERS
- 9 Hepatocellular Carcinoma: Epidemiology, Pathology, Diagnosis and Screening
- 10 Staging Systems for Hepatocellular Carcinoma
- 11 Hepatocellular Carcinoma: Medical Management
- 12 Surgical Management (Resection)
- 13 Liver Transplantation for Hepatocellular Carcinoma
- 14 Image-guided Ablation of Hepatocellular Carcinoma
- 15 Embolization of Liver Tumors: Anatomy
- 16 Transcatheter Arterial Chemoembolization: Technique and Future Potential
- 17 New Concepts in Targeting and Imaging Liver Cancer
- 18 Intrahepatic Cholangiocarcinoma
- 19 Medical Management of Colorectal Liver Metastasis
- 20 Surgical Resection of Hepatic Metastases
- 21 Clinical Management of Patients with Colorectal Liver Metastasis Using Hepatic Arterial Infusion
- 22 Colorectal Metastases: Ablation
- 23 Colorectal Metastases: Chemoembolization
- 24 Radioembolization with 90Yttrium Microspheres for Colorectal Liver Metastases
- 25 Carcinoid and Related Neuroendocrine Tumors
- 26 Interventional Radiology for the Treatment of Liver Metastases from Neuroendocrine Tumors
- 27 Immunoembolization for Melanoma
- 28 Preoperative Portal Vein Embolization
- 29 Cancer of the Extrahepatic Bile Ducts and the Gallbladder: Surgical Management
- 30 Extrahepatic Biliary Cancer: High Dose Rate Brachytherapy and Photodynamic Therapy
- 31 Extrahepatic Biliary Cancer/Biliary Drainage
- 32 Surgical and Medical Treatment
- 33 Percutaneous Renal Ablation
- 34 Embolotherapy in the Management of Renal Cell Carcinoma
- 35 Epidemiology, Diagnosis, Staging and the Medical-Surgical Management of Lung Cancers
- 36 Image-guided Ablation in the Thorax
- 37 Interventional Treatment Methods for Unresectable Lung Tumors
- 38 Interventional Neuroradiology in Head and Neck Oncology
- 39 Percutaneous Ablation of Painful Metastases Involving Bone
- 40 Intra-arterial Therapy for Sarcomas
- 41 Prostate Cryoablation: A Role for the Radiologist in Treating Prostate Cancer?
- PART IV SPECIALIZED INTERVENTIONAL TECHNIQUES IN CANCER CARE
- INDEX
- Plate section
- References
Summary
Surgical resection has been the mainstay of treatment for the minority of patients diagnosed with primary lung cancer and for selected patients with pulmonary metastatic disease. However, most patients with thoracic malignancies have little recourse other than the modest therapeutic benefits of chemotherapy or radiotherapy, which offer little chance for quality, prolonged survival.
Thermal ablation is an exciting new technique that offers clinicians and patients new hope with a repeatable, effective, low-cost, and safe treatment to effectively palliate and, in some cases, cure both primary and metastatic thoracic malignancies either before or concurrent with systemic therapy and radiotherapy.
The natural history of thoracic malignancies is of locoregional treatment failure and distant recurrence, except for non-small cell, primary lung cancers less than 2 cm in diameter, for which the likelihood of regional (extra-segmental) spread is small and surgery may be most appropriate. Although thermal ablation strategies have been used in patients with primary lung cancer who are too sick or have disease burdens that are too great for surgical therapy, most thoracic oncologists now recognize that primary lung cancer, like metastatic lung cancer, is a systemic disease with bewildering heterogeneity at the start, and that effective, local palliation and systemic therapy for both primary and metastatic thoracic cancer is the goal.
In this chapter, we discuss the basic physics of thermal ablation, applications for thermal ablation therapy in the thorax and technical considerations for thermal ablation.
- Type
- Chapter
- Information
- Interventional OncologyPrinciples and Practice, pp. 440 - 474Publisher: Cambridge University PressPrint publication year: 2008
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